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Displaying 1701 - 1720 of 3528 records Index

Oral Stakeholder involvement in the preparation of systematic and rapid reviews: a cross-sectional study

2017 Cape Town [Global Evidence Summit]
Mütsch, Feldmann, Puhan
Background: To foster knowledge transfer and implementation it is considered essential to involve stakeholders in the preparation of systematic reviews (SR) and rapid reviews (RR). To date, little is known about the types of stakeholders involved and details of their engagement. Objectives: In…

Oral Strategies to improve participant recruitment to randomised-controlled trials: A systematic review of non-randomised evaluations

2017 Cape Town [Global Evidence Summit]
Gardner, Treweek, Gillies
Background: Poor recruitment to randomised-controlled trials is common, and has the potential to result in underpowered studies which do not satisfactorily answer research questions. Trial-recruitment strategies attempt to support recruitment, yet evidence to support the choice of recruitment…

Oral Systematic approach to guide the Lancet Commission on Syria: The case of healthcare workers in conflict settings

2017 Cape Town [Global Evidence Summit]
Bou Karroum, Akl, El-Jardali, Fadlallah
Background: The violent conflict in Syria has caused the largest humanitarian crisis of our time. To raise the profile of the Syrian crisis in global health and mobilise a stronger international response, The Lancet and the American University of Beirut (AUB) launched the ‘Lancet Commission on…

Oral Systematic review and meta-analysis of prevalence and single group continuous data: methodological and practical challenges and benefits

2017 Cape Town [Global Evidence Summit]
Jadotte, Holly, Salmond, Benenson, Paplanus, Thompson-Stewart
Background: Systematic reviews and meta-analyses of evidence from studies other than RCTs are becoming more prevalent. In particular, meta-analysis of prevalence and single-group continuous data is an important new application of evidence synthesis for decision making. While there are published…

Oral Systematic reviews assessed as high risk of bias due to avoidable failures in searching: analysis of a data set of critically appraised systematic reviews

2017 Cape Town [Global Evidence Summit]
de Kock, Stirk, Noake, Deshpande, Misso, Kleijnen, Duffy
Background: A substantial number of systematic reviews (SR) are failing to follow recommendations for the conduct and reporting of search methods despite the availability of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and the Cochrane Handbook for Systematic Reviews…

Oral TRiads-P: A translational research programme to promote evidence-based practice in the community pharmacy setting

2017 Cape Town [Global Evidence Summit]
Watson, Cassie, Duncan, Power, Young, Cooper, Newlands, Bonetti
Background: TRiads-P is a national, translational research programme funded by NHS Education for Scotland (NES) which adopts a co-ordinated approach using behavioural and theoretical research to achieve quality improvement in community pharmacy services. Objectives: To improve the quality of…

Oral The CREATE Critical Appraisal Tool: A Tool To Appraise Research From Aboriginal and Torres Strait Islander Perspectives

2017 Cape Town [Global Evidence Summit]
Harfield, Gibson, Morey, Kite, Canuto, Glover, Streak Gomersall, Davy, Carter, Aromataris, Braunack-Mayer
Background: In health research, systematic reviews are widely used to guide decision makers towards implementing best practice in policy and healthcare. Systematic reviews that assess and synthesise the best-available evidence on questions relevant to Aboriginal and Torres Strait Islander community…

Oral The Development of an Evidence Guideline for Traumatic Brain Injuries

2017 Cape Town [Global Evidence Summit]
Ott, Muthe, Eden, Hegmann, Hegmann, Harris
Background: Traumatic brain injury (TBI) has been estimated to affect 1.7 to 10 million people annually in the general United States population. TBI may occur less frequently in the workplace compared to other injuries, but it carries enormous per capita costs, in large part due to vocational…

Oral The UpPriority Tool: Development of a prioritisation tool for updating clinical guideline questions

2017 Cape Town [Global Evidence Summit]
Martínez García, Pardo-Hernandez, Niño de Guzman, Superchi, Ballesteros, McFarlane, Posso, Roqué i Figuls, Sanabria, Selva, Sparrow, Vernooij, Alonso-Coello
Background: Due to the continuous emergence of new evidence, clinical guidelines (CGs) require regular surveillance of evidence to maintain their trustworthiness. Updating CGs is resource-intensive and time-consuming; therefore, updating may include a prioritisation process in order to efficiently…

Oral The area under the ROC curve may be a biased performance measure for meta-analysis of diagnostic accuracy studies. A simulation study

2017 Cape Town [Global Evidence Summit]
Wang, Leeflang
Background: In systematic reviews of diagnostic accuracy studies, summary estimates of sensitivity and specificity and summary ROC curve are the preferred test-performance measures. In some of the recent systematic reviews, area under summary ROC (AUSROC) curve is also reported as an overall…

Oral The challenge of assessing quality and synthesising evidence: Lessons from an overview of systematic reviews of economic evaluations of vaccination programmes

2017 Cape Town [Global Evidence Summit]
Hadnorntun, Bangpan, Taychakhoonavudh, Thavorn, Ng, Chaiyakunapruk
Background: Although there are a large number of published systematic reviews (SRs) of economic evaluations (EEs) of vaccination programs used to support policy decision making, the overall summary of findings from these SRs lacks of consensus, and the overall quality of these SRs has not been…

Oral The effectiveness of budget support – a synthesis study

2017 Cape Town [Global Evidence Summit]
Orth, Krisch, Schmitt
Background: Budget support became increasingly popular towards the second half of the 2000s as the most consequential aid instrument for implementing the principles of effective aid formulated in the 2005 Paris Declaration. Although evaluations found that budget support contributed to improved…

Oral The impact of public comments on the development of methodology standards for patient-centred outcomes research

2017 Cape Town [Global Evidence Summit]
Totten, Hickam
Background: Comparative-effectiveness research has the potential to improve the evidence needed by patients and clinicians to make individualised choices among healthcare options. New evidence must be grounded in good science and methodology standards provide the basis for scientific integrity.…

Oral The importance of minimal important differences to inform systematic reviews and clinical practice guidelines: an example

2017 Cape Town [Global Evidence Summit]
Devji, Guyatt, Lytvyn, Brignardello-Petersen, Foroutan, Sadeghirad, Buchbinder, Harris, Carrasco-Labra, Siemieniuk, Vandvik
Background: Investigators increasingly rely on patient-reported outcome measures (PROMs) as key end points in clinical trials. However, interpretation of the magnitude of treatment effects on PROMs presents challenges. The smallest change that patients perceive as important – the minimal important…

Oral The role of reviewer reflexivity: reflections from a mixed-method consultative systematic review

2017 Cape Town [Global Evidence Summit]
Rees, Sutcliffe, Dickson, Thomas
Background: Qualitative evidence syntheses (QES) use systematic methods to seek out and make sense of qualitative research findings, including people’s accounts of their views and experiences. They can help us understand health conditions, health behaviours and interventions from the perspectives…

Oral The use of a Theory of Change model in a mixed-methods systematic review (MMSR): an example from the Development Aid sector.

2017 Cape Town [Global Evidence Summit]
Van Remoortel, De Buck, Vande veegaete, Govender, Hannes, Vandekerckhove, Young
Background: A Theory of Change (ToC) is a comprehensive description and illustration of how and why a desired change is expected to happen in a particular context. The use of a ToC, and collecting data on outcomes along the causal chain, can be helpful in attempts to explain effect-size…

Oral Tools and resources for a rapid-response service to meet policy makers' urgent needs for evidence

2017 Cape Town [Global Evidence Summit]
Mijumbi-Deve, Kawooya, Sewankambo
Background: As the calls for evidence-informed decision and policy making increase, there is an emphasis on the evidence not only being relevant but timely too. And therefore there is a growing interest in rapid-response services which use rapid syntheses of evidence like rapid-response briefs to…

Oral Transitioning to living systematic reviews: Lessons learned from a large scale review on diabetes quality improvement interventions

2017 Cape Town [Global Evidence Summit]
Sullivan, Grimshaw, Danko, Dahabreh, Karunananthan, Gall Casey, Sundaramoorthy, Ivers
Background: Evidence evaluating quality improvement (QI) strategies designed to optimise diabetes management is rapidly growing, with almost 20 new RCTs published in English annually. Using traditional systematic review (SR) methods to synthesise this evidence is no longer sustainable, as reviews…

Oral Understanding the evidence-informed decision-making landscape in Africa: actors, engagement and skills

2017 Cape Town [Global Evidence Summit]
Erasmus, Langer, Stewart
Background: Evidence in various forms - whether it is primary research, evidence mapping, or evidence synthesis products - needs to be perceived as useful in order to be used by decision makers. It is therefore important to understand how engagement occurs that facilitates research uptake; who the…

Oral Uniqueness of conducting systematic reviews and developing nutrition practice guidelines: Experiences and challenges from Academy’s EAL

2017 Cape Town [Global Evidence Summit]
Handu, Moloney
Objective: To understand and learn the challenges in conducting systematic reviews and developing guidelines in the field of nutrition. Background: The Academy’s Evidence Analysis Library (EAL) conducts stand-alone systematic reviews (SRs) and SRs that inform Evidence-based Nutrition Practice…