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Displaying 81 - 100 of 295 records Index
Poster Comparative analysis of clinical trials in psychotherapy and pharmacotherapy for treatment of depression
2023 London
Helfer
Background: Extensive evidence-based literature exists on the comparative merits of talking therapies and using antidepressant medication for the treatment of depression. However, clinical research concerning psychotherapy and pharmacotherapy is often divided along disciplinary lines, and key…
Poster Comparison of several systematic review process software tools among health care professionals: A questionnaire based survey.
2023 London
Mishra, Panda, Mohanty
Background: Systematic reviews are an important tool for synthesizing and summarizing evidence in healthcare research. There are numerous software tools available for conducting systematic reviews, but it is unclear which tools are most commonly used or most effective among healthcare professionals…
Poster Comparison of diagnostic test accuracy estimates using the Multiple Thresholds Model based on complete and published cut-off data with a bimodal reporting pattern
2023 London
Fomenko, Linde, Aktürk, Schneider, Rücker, Hapfelmeier
Background:
The multiple thresholds (MT) model allows for diagnostic test accuracy (DTA) meta-analysis of multiple cutoffs simultaneously. Previous analyses demonstrated the ability of the MT model to approximate DTA estimates of a complete cutoff dataset, based on reported cutoffs. This has been…
Poster Comparison of the methodological quality of RCTs using RoB-2 and JBI tools: performing of medical students
2023 London
Merlano Madera, Guzmán Medrano, Reyes Altamar, Madera
Background: The risk of bias assessment is an essential step during the development of systematic reviews, which have an important role in the decision-making process and the translation of evidence into practice. Among the instruments to assess the methodological quality of randomized clinical…
Poster Competency profiles for Evidence-Informed Policy (EIPM): a rapid review
2023 London
Barreto, Romão, Setti, Machado , Riera, Gomes, Fernandes
Background: Evidence-Informed Policy-making (EIPM) requires a set of individual and organizational capabilities, articulated with background factors and needs. The identification of essential Knowledge, Skills and Attitudes for EIPM can support the formulation of competency profiles and their…
Poster Competing events and in-hospital follow-up: issues to be aware of
2023 London
Sandercock, Geneen, Kimber, Lamikanra
Background:
In our review of convalescent plasma or hyperimmune immunoglobulin for severe respiratory viral infections, with 30 randomised controlled trials (RCTs), several outcomes were complicated by competing events and in-hospital follow-up.
Survival:
Only one trial (RECOVERY) of seven…
Poster Concept for teaching medical students evidence-based and Cochrane methods
2023 London
Harst, Deckert, Rüthrich, Haase, Kösters
Background: Scientific methods eke out a niche existence in the education of physicians in Germany. A new model study program in Chemnitz, Germany highlights the importance of scientific methods for medical students. A cornerstone in education is the conduct of systematic reviews in line with the…
Poster Conflicts Of Interest and Risk of Bias In Systematic Reviews On Interventions For 6 Common Diagnoses in Primary Care
2023 London
Czajkowski, Snellman , Olsson
Background
Knowledge on the association between disclosed conflicts of interest (COI) and risk of bias (RoB) in systematic reviews (SRs) is limited, especially from a clinical perspective.
Objectives
We aimed to explore the association between COI and RoB in a recent sample of SRs of clinical…
Poster Consistency of protocol and safety data reporting in clinical trial registrations and corresponding publications of interventions involving 3,4-methylenedioxymethamphetamine (MDMA)
2023 London
Žuljević, Mijatović, Gujinović, Duplančić
Background: The efficacy of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for patients with post-traumatic stress disorder (PTSD) has been demonstrated in clinical trials, although this remains controversial owing to the classified status of the substance in most countries and the…
Poster Construction of minimum data set for core outcome set in real-world settings: A data-driven approach
2023 London
Han
Background: Hundreds of core outcome sets (COS) have been developed for standardized outcome reporting in clinical trials, whereas their usage in real-world settings is largely limited because of the data availability and difficulty in data cleansing. Although a few COS have matched core data sets…
Poster Contextualizing evidence-based nurse-led peri-discharge interventions for reducing 30-day hospital readmissions using GRADE Evidence to Decision Framework: A Delphi study
2023 London
ZHONG, Wong, Hung, Yeoh, Wong, Chung
Background: Effectiveness of nurse-led peri-discharge interventions on 30-day hospital readmissions has been synthesized in previous network meta-analysis. However, generalizability of such results is expected to vary in health system contexts given their complexity.
Objectives: To translate…
Poster Contribution of the new rehabilitation definition to possibly improve related Cochrane Systematic Reviews
2023 London
BATTEL, Arienti, Levack, Kiekens, Negrini
Background:
Cochrane Rehabilitation (CR) developed, with all global relevant stakeholders, a new rehabilitation definition (Table 1). The next step in the project was to understand its value in discerning rehabilitation studies from those that were not specifically rehabilitative.
Objectives:…
Poster Core outcome set development for intervention research on snakebite in South Asia: methodological case study
2023 London
Bhaumik, COS-Snakebite-South-Asia-Group
Background:
Core outcome set (COS) are a consensus-derived set of outcomes that should be minimally measured in future research or practice for a specific condition. A COS for intervention research on snakebites in South Asia was developed, and several new methodological insights were obtained.…
Poster Creating accessible patient guidelines based on oncological evidence-based clinical practice guidelines
2023 London
Oeser, Messer, Holtkamp, Follmann, Langer, Wenzel, Skoetz
Background: To make informed decisions, patients need reliable information on their disease. In Germany, some evidence-based clinical practice guidelines, for example on haematological malignancies, are being prepared in cooperation with the German Guideline Program in Oncology (GGPO), funded by…
Poster Crowdsourcing trainees in a living systematic review provided valuable experiential learning opportunities: a mixed-methods study
2023 London
Lee, Thomas, Ejaredar, Kassam, Whittle, Buchbinder, Tugwell, Wells, Pardo Pardo, Hazlewood
Background: Evidence-based medicine educators are continually looking for new ways to engage trainees in experiential learning. Living systematic reviews (LSRs) could serve as a mechanism for ensuring an ongoing opportunity for this type of learning.
Objectives: To understand trainee experiences…
Poster Current status of the national clinical research program producing trusted evidence in Korea
2023 London
Kim, Cho, Son, Shin, Lee, Jung, Heo
“Patient-Centered Clinical Research Coordinating Center Program (PACEN)” is the largest investigator-initiated research program funded by the Korean government for public interest. It supports practical research for comparative assessment or evidence-generation of health technologies used in…
Poster Decision makers find it difficult to compare and select similar systematic reviews based on quality, methods and results: a cross-sectional survey
2023 London
Lunny, Whitelaw, Chi, Zhang, Ferri, Kanji, Pieper, Shea, Dourka, Veroniki, Ardern, Pham, Reid, Bagheri, Tricco
Background: Systematic reviews (SRs) are being published at an accelerated rate. Decision-makers are often faced with the challenge of comparing and choosing between multiple SRs on the same topic.
Objectives: We surveyed individuals in the healthcare field to understand what criteria they use to…
Poster Defining misinformation and related terms: a scoping review of the health-related literature
2023 London
El Mikati, Hoteit, Harb, El Zein, Piggott , Melki, Akl, Mustafa
Background: Misinformation poses a serious challenge to clinical and policy decision-making in the health field, which relies on accurate and reliable information. The COVID-19 pandemic amplified interest in misinformation and related terms and witnessed a proliferation of definitions.
Objectives…
Poster Determining the inter-reviewer reliability of literature screening for human and machine-assisted systematic reviews: A mixed methods review
2023 London
Hanegraaf, Wondimu, Mosselman, De Jong, Abogunrin, Queiros, Lane, Postma, Boersma, Van der Schans
Background:
Automating aspects of the systematic literature reviews (SLRs) process could lead to better and up-to-date informed medical decision-making, and therefore improved health outcomes for individual patients. Machine learning automation has been proposed to reduce the workload and…
Poster Developing a core outcome set for assessing clinical safety outcomes of cardiovascular diseases in clinical trials of integrated traditional Chinese medicine and Western medicine
2023 London
Qiu, Wan, Guan, Zhang, Zhong, Wang, Wei, Fan, Shang
Background: Integrative medicine is commonly used in China. Researchers prefer to report efficacy outcomes rather than safety outcomes in clinical trials; thus, evidence regarding harms in integrative medicine is unclear. Developing a core outcome set (COS) for harms is necessary.
Methods:…