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Workshop A hands-on introduction to NMAstudio: a web-application to produce and visualize network meta-analyses

Chaimani, Yu, Metelli
Background: Evaluation of network meta-analysis (NMA) evidence can be challenging and time-consuming, especially when dealing with large networks of interventions. Despite the fact that NMAs are increasingly adopted to inform decision-making, the lack of user-friendly software is still limiting…

Workshop How to plan and implement synthesis questions (part 2): Implementing PICO in RevMan to streamline data extraction and analyses

Flemyng, Van Valkenhoef, Sambunjak, Brennan, McKenzie, Cumpston, Arevalo-Rodriguez, Hall
Participants will need to bring their own laptop. Background: This is the second of a two-part workshop. Defining your review ‘question’ (the objective) and developing criteria for including studies in the review using the PICO framework is a fundamental step in a systematic review. As well as…

Workshop Introduction to meta-analysis 2: dealing with heterogeneity

Simmonds, Tsokani
Background: The studies in a meta-analysis may vary in their included populations, how the intervention of interest was used, how outcomes were assessed, and in study design and conduct. This variability in study properties may lead to variability in the outcomes across studies. This variability…

Workshop Integrating the findings of a qualitative evidence synthesis (QES) with the findings of a review of intervention effects

Sutcliffe, Noyes, Harden, Ames, Houghton, Thomas, Pantoja, Garside, Booth, France , Flemming
QMIG Methods Workshop Background: Methods for qualitative evidence synthesis (QES)—a systematic review method for bringing together qualitative studies—are now well established, and decision-makers are able to access rigorous QES on issues such as patient experiences and contextual factors…

Workshop Comparing multiple interventions with network meta-analysis

Chaimani, Caldwell, Li
Background: Standard meta-analysis methods for clinical trials focus on comparisons of two interventions, such as a drug versus placebo or a new intervention versus standard practice. In clinical practice, there are rarely only two interventions under consideration. Extensions of meta-analysis to…

Workshop Advanced meta-analysis 2: Performing meta-analysis in the presence of rare events

Chaimani, Evrenoglou
Background: Rare events are a common problem in meta-analysis, particularly for secondary and safety outcomes. When the events are rare, standard meta-analytical approaches have important limitations and may lead to biased and imprecise results. Alternative methods have been proposed in the…

Workshop If, when and how to sample primary studies for inclusion in a qualitative evidence synthesis

Ames, Noyes, Sutcliffe, Thomas, Houghton, Pantoja, Harden, Booth, Garside, France, Flemming
Background: Too much data can threaten the quality of a data synthesis in a qualitative evidence synthesis (QES), and too little can limit transferability across multiple contexts. As a QES seeks to provide an interpretation of the evidence, it is not essential to identify and include every…

Workshop Performing and disseminating review findings through art and design

Perold-Bull, Hannes, Hendricks, Cooper, Dawson, Schmidt
Background: Interest in using multimodal, arts-based methods in the context of health-related research has been increasing recently. Its value lies not only in its ability to unearth complex, rich and nuanced data but also in how the process/processes can simultaneously facilitate the…

Workshop Producing Trusted Evidence: Identifying the Challenges and Finding the Solutions

Whear, Abbott
Background: Having mapped the nature, scope, and quality of evidence syntheses on COVID-19 to explore the relationship between review quality and the extent of researcher, policy, and media interest, we found low quality reviews being published at pace, often with short publication turnarounds.…

Workshop MetaDTA and MetaBayesDTA: Interactive web applications to conduct meta-analysis of diagnostic test accuracy studies

Cooper, Nevill, Sutton, Freeman
Background Diagnostic tests form an essential part of current medical practices aiming to distinguish between patients with the disease and healthy individuals. They are used across a diverse range of healthcare settings and are often a pre-requisite to identifying treatment options and enabling…

Workshop MetaInsight: An interactive user-friendly “point and click” web application to conduct network meta-analysis

Cooper, Nevill, Sandercock, Sutton, Bradbury
Background Network meta-analysis (NMA) allows the comparison of multiple competing interventions for a condition. Such analyses have become very popular due to their relevance for clinical decision-making. MetaInsight ((https://crsu.shinyapps.io/MetaInsight/) is a freely available user-friendly…

Workshop Conducting Rapid Qualitative Evidence Synthesis: Why, when and how?

Houghton, Booth
QMIG Methods workshop: Background: As we learned from the COVID-19 pandemic, sometimes questions need to be answered quickly in order to be useful for policy and practice. This applies equally to questions answerable by qualitative evidence synthesis. However, providing evidence quickly may…

Workshop Practical advice for accessing patient-level data from a data sharing platform for evidence synthesis

Wood, Sudlow, Tudur Smith, Li
Background: Since 2014, opportunities to request and access the patient level datasets collected in a clinical trial have become more commonplace. Vivli is an independent, non-profit organisation that has developed a global data-sharing and analytics platform. Patient-level data is available from 7…

Workshop How to incorporate information on funding and conflicts of interest in trials when conducting a Cochrane Review: the TACIT tool

Lundh, Hróbjartsson, Boutron, Stewart
Background: Industry funding and trial researchers’ financial conflicts of interest are common in clinical trials and are associated with favourable trial conclusions and seemingly greater treatment effects. Information on funding and conflicts of interest is therefore considered important when…

Workshop Assessing risk of bias in comparative diagnostic accuracy studies using QUADAS-C

Yang, Leeflang
Background: Diagnostic Test Accuracy reviews addressing comparative questions may include studies directly comparing index tests in the same study group. Because these comparative accuracy studies aim to estimate the difference in accuracy between tests (rather than solely the accuracy of each test…

Workshop Health Equity: Implications for Systematic Reviews

Welch, Magwood, Tomlinson, Spiga
Background: This is a core training session from a Cochrane Methods Group. The Cochrane Handbook for Systematic Reviews of Interventions includes a chapter on equity and specific populations. A Cochrane Interactive Learning module has been developed to accompany this chapter. This workshop aims…

Workshop Consumer Involvement 101: producing Cochrane evidence with consumers

Morley, Todhunter-Brown, Smith, Pizarro, Plachcinski
Background: This workshop is for researchers and consumers who are interested in involving people in producing systematic reviews, and it aims to address the questions that people have, share the different possible methods, and explore the resources and support that are available. By the end of…

Workshop Systematic reviews of prognosis studies IV: The use of GRADE for assessing the certainty of evidence for questions of overall prognosis and prognostic factors

Foroutan, Guyatt, Kreuzberger, Iorio, Moons, Riley
Background The GRADE approach is widely used for assessing certainty in inferences drawn from evidence. The GRADE approach has been adopted to assess certainty in evidence on overall prognosis and prognostic factors. Objective Present participants with an interactive session designed to…

Workshop Introduction to analysis and meta-analysis of interrupted time series studies

Korevaar, Turner, McKenzie, Forbes, Karahalios, Taljaard
Background: Interrupted Time Series (ITS) studies are commonly used to evaluate public health and policy interventions when randomisation is impractical or infeasible; for example, examining the effects of mass media campaigns on the use of methamphetamine among young adults. In an ITS study,…

Workshop Storyboarding as a multimodal analytical technique in a qualitative evidence synthesis

Hendricks, Hannes, Perold-Bull, Dawson, Young, Young
Background: Multimodality is centralized around the fundamental question of how to use and combine modes of expression to organize, analyze, synthesize, interpret, and share research evidence. The use of multiple, engaging modalities, for example words in combination with images, establishes new…