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Displaying 21 - 40 of 2108 Index
Oral Beyond Statistical Significance: Investigating How Systematic Review Authors Communicate Meaningful Differences of Nonsignificant Results
2023 London
Persad, Emprechtinger, Ledinger, Chapman, Gadinger, Feyertag, Gartlehner
Background: For decades, statisticians and methodologists have severely criticized the undue reliance on strict p-value thresholds (usually 0.05) and the misinterpretation of statistical significance in medical research. Despite legitimate criticism, primary research and systematic reviews continue…
Oral Boosting global and local partnerships to promote equitable access of COVID-19 guideline recommendations: case study in China
2023 London
Chi, Xia, Yao, Motilall, Lotfi, Schünemann
Background: The eCOVID19 Recommendations Map and Gateway to Contextualization (RecMap) is a living platform presenting 7280 guideline recommendations. Funded by the Canadian Institute of Health Research (CIHR), RecMap involves the collaboration of over 40 partner organisations globally and has…
Oral Breaking Ground or Breaking Bad? Examining the Fate of Preprints in Prevention Research with a Mixed Methods Study
2023 London
Sommer, Sunder-Plassmann , Dobrescu , Griebler, Gartlehner
Background:
The availability of unsound or scientifically invalid work is a concern associated with preprint articles. The popularity of preprints in prevention research has increased due to the COVID-19 pandemic.
Objectives:
The objectives of this study were to assess the consistency of results…
Oral Bringing Cochrane reviews to Polish professionals and consumers
2023 London
Zajac, Koperny, Dziadyk, Bala
Background: Improving health literacy and increasing the use of reliable health information may reduce vulnerability to unreliable health-related information. Health professionals may help in translating the knowledge to nonprofessionals, but they often find it challenging.
Objectives: To show our…
Oral Bringing a patient perspective to understanding interventions that aim to reduce length of stay in hospital: a mixed methods synthesis
2023 London
Thompson Coon, Nunns, Febrey, Shaw, Kinsey, Briscoe, Carrieri, Lovegrove, Hemsley, McGrath, Kneale
Background:
Hospital-led, multicomponent organisational strategies that aim to enhance recovery after surgery are associated with improved clinical outcomes. Less is known about aspects of interventions or their delivery which can lead to better patient outcomes.
Objectives:
To establish which…
Oral Building acceptance for machine learning in study selection within a systematic review institution: Experiences from the Norwegian Institute of Public Health
2023 London
Ames, Jardim, Borge, Hestevik, Himmels, Meneses-Eschavez
Background:
The Norwegian Institute of Public Health’s (NIPH) machine learning (ML) implementation team within the Cluster for Reviews and Health Technology Assessments sprung from the need to produce more health technology assessments and systematic reviews, faster, during the COVID-19 pandemic.…
Oral Building capacity in producing trusted evidence – Evidence Synthesis Ireland and Cochrane Ireland Fellowships
2023 London
Burke, Toomey, Healy, Devane
Background:
Evidence Synthesis Ireland (ESI), which includes Cochrane Ireland, aims to build evidence synthesis knowledge, awareness and capacity among the public, healthcare institutions, policymakers, clinicians and researchers on the island of Ireland. One way we do this is through the ESI…
Oral CEOsys – An ecosystem for COVID-19 evidence in Germany: challenges and lessons learned as a guide for future networks
2023 London
Kunzler, Iannizzi, Moerer, Nothacker, Rehfuess, Spies, Skoetz, Meerpohl, and the CEOsys Consortium
Background: The COVID-19 pandemic presented a major disruption worldwide. Given the extensive, rapidly evolving evidence, high-quality evidence syntheses that provide context-sensitive and up-to-date data were urgently needed as a basis for evidence-informed clinical and public health decision-…
Oral Can we reduce the workload of systematic reviews without compromising quality? A new platform to accelerate search and study identification
2023 London
Verdugo-Paiva, López-Alcalde, Alonso-Coello, Stallings, Jiménez, Zamora, Rigau, Ramos, Rada, Solà
Background: The development of systematic reviews (SRs) is resource intensive. The Sustainable Knowledge Platform (SK platform) is a new system that streamlines all the steps of SRs, applying technology to make the process efficient. It includes a comprehensive taxonomy, as well as off-the-shelf…
Oral Can we use GRADE to create new diagnostic criteria for a condition? An application of GRADE principles for establishing diagnostic criteria for a disease
2023 London
Munn, Reid
Background:
Although it is critical to consider downstream consequences of changing disease definitions and to avoid the perils of overdiagnosis, disease definitions and diagnostic criteria are sometimes required to be developed, modified, or updated. In 2021, a group in Australia was tasked with…
Oral Capturing the primary outcome for Cochrane reviews of deprescribing specific medications: an overview of Cochrane reviews
2023 London
Van Leeuwen, Thompson, GNJIDIC, Spinewine, Reeve, Van Driel, Christiaens
Background:
Deprescribing is the process of discontinuing an inappropriate medication. Research into deprescribing has grown rapidly in recent years, including a number of Cochrane systematic reviews (CR). It is important to study whether discontinuation can be done successfully without an…
Oral Challenges and innovations in evidence synthesis and evaluation during the COVID-19 pandemic
2023 London
Zeraatkar, Chen, Huynh, Sattar, Shahab
Background: The COVID-19 pandemic instigated unprecedented challenges for clinical and policy decisions. In response to these challenges, the pandemic also resulted in much-awaited innovations.
Objective: To perform a scoping review describing challenges and innovations in evidence synthesis and…
Oral Challenges and potential solutions for reporting findings from multicomponent meta-regression models in GRADE summary of findings tables
2023 London
Konnyu, Trikalinos, Yogasingam, Ivers, Grimshaw
Background: We recently completed a Cochrane review of diabetes quality improvement (QI) trials that aimed to identify promising QI strategies (or combinations of strategies) to deploy in practice or examine in future research. We coded interventions according to the presence of absence of 12 QI…
Oral Challenges in using RoB2: worked example from a systematic review of remote therapies for alcohol and drug misuse.
2023 London
D'Souza, Khwan, Macdowall, Burchett, Sutcliffe
Background:
RoB 2, the revised Cochrane tool for assessing risk of bias in randomized controlled trials (RCTs), aims to increase the reliability of assessments.
Objectives:
To share our experience of using RoB 2 in a systematic review on remote alcohol and drug misuse therapies.
Methods…
Oral Challenges of coordinating large-scale systematic reviews
2023 London
Yogasingam, Lepine, Sullivan, Antony, Konnyu, Ivers, Grimshaw
Background: Large-scale systematic reviews are becoming more common owing to the rapid growth in publications on certain topics. They raise unique challenges for managing and coordinating the review process for which there is limited guidance. We will present the challenges we encountered and how…
Oral Characteristics, reporting, and methods of trials included in time-to-event meta-analyses of systematic reviews: A meta-epidemiological review
2023 London
Goldkuhle, Kreuzberger, Hirsch, Iannizzi, Bora, Bender, Van Dalen, Hemkens, Skoetz
Background:
Previous studies demonstrated limitations in the reporting of time-to-event (TTE) analyses in trial publications. The challenges that systematic review authors face in trials they include for TTE meta-analysis remain unexplored.
Objectives:
To explore the characteristics, reporting…
Oral ChatGPT and large language models for systematic review tasks: What are the opportunities for improvement?
2023 London
Qureshi, Shaughnessy, Gill, Robinson, Li, Agai
Background: The advancement of Artificial Intelligence (AI) assisted technologies leave many wondering about the current capabilities, limitations, and opportunities for integration into scientific endeavors. Large language models (LLM) – such as ChatGPT, designed by OpenAI – have recently gained…
Oral Co-Producing a resource for intervention development: The Nature on Prescription Handbook.
2023 London
Fullam, Hunt, Lovell, Husk, Orr, Garside
Background and Objective: There is increased interest in nature-based interventions (NBIs) to support mental health. These interventions are complex, operating across sectors, with a variety of activities, populations and environments. Previous research has highlighted poor elucidation of how and…
Oral Co-designing outcomes for a review on self-harm and suicide prevention interventions: Are we failing our young people?
2023 London
Sharma, Prescott, Churchill, Fortune, Marshall, Hetrick
Background:
Involvement of end users in the production of reviews has mostly been limited to consultative review of researcher-authored protocols with involvement in outcome identification far less common. To address this gap, for a recent Cochrane review on suicide and self-harm prevention…
Oral Cochrane Rehabilitation Blogshot translation: a partnership model of evidence dissemination
2023 London
Freitas, Santos, Arienti, Negrini, Bekkering, Giraldo-Prieto, Lugo-Agudelo, Casino, Li, Vaz Carneiro, Pillai, Barth, Kiekens
Background: Rehabilitation is a health strategy to enable people with disabilities to reach and maintain their optimal physical, sensory, intellectual, psychological, and social functional levels. Cochrane Rehabilitation aims to ensure that all rehabilitation professionals apply Evidence-Based…