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Poster Addressing racial health inequity: systematic review of systematic reviews
2023 London
Welch, Viswanathan, Dewaidar, Rizvi, Terhune, Duque, Francis, Riddle, Heyn, Pizarro
Background: Racialized populations are affected by the sociopolitical and historical context in which they live. For example, African American and Black people face persistent discrimination and exclusion in the United States. Reducing racism and its negative consequences is a key global priority…
Poster Adequacy of information on funding and financial conflicts of interest in clinical trial publications and how to obtain missing information: methodological study
2023 London
Ivosevic, Faltinsen, Hróbjartsson, Lundh, Hansen Nejstgaard
Background: Knowledge about funding and authors’ conflicts of interest is important when critically appraising trials, for example in the context of a systematic review. Although studies have found that funding and conflicts of interest information is often reported in trial publications, little is…
Poster Adherence and quality of systematic reviews for automatically registered protocols: a PROSPERO register study
2023 London
Luo, Liu, Zhu, Wang, Chen
Background:
Following the emergence of the COVID-19 pandemic, the PROSPERO team established an automated checking procedure for non-COVID-19 systematic reviews that are registered on their platform. This process takes place 30 days after registration. Nevertheless, it remains uncertain whether the…
Poster Adherence of Cochrane reviews and protocols to the Cochrane's risk of bias 2.0 tool
2023 London
Martimbianco, Sá, Santos, Santos, Pacheco, Riera
Background: Assessing the risk of bias in individual studies is an important step when conducting a systematic review and key criteria for assessing the certainty of the body of evidence. Neglecting potential biases can directly impact the estimated effects of the intervention, lead to uncertain…
Oral Adherence to PRISMA 2020 statement in non-Cochrane systematic reviews of interventions. A meta-epidemiological study
2023 London
Ivaldi, Burgos, Oltra, Escobar Liquitay, Garegnani
Background:
Evidence-based medicine (EBM) is defined as the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of patients by integrating individual clinical expertise, the best available clinical evidence, and the individual patient’s preferences…
Poster Adherence to non-financial conflicts of interest policy in Cochrane reviews where authors are also editorial board members
2023 London
Pacheco, Latorraca, Martimbianco, Fontes, Miranda, Nunan, Riera
Background: Conflict of interest (COI) represents a major threat to the validity of research, and its impact is well recognized and has been extensively addressed in the literature [1,2]. The impact of nonfinancial conflict of interest (nfCOI) in conducting systematic reviews is not ignored by…
Workshop Advanced meta-analysis 1: Random-effects methods to be implemented in RevMan
2023 London
Veroniki, McKenzie, Korevaar, Turner
Background: Meta-analysis is typically used to estimate the mean effect size of an outcome of interest. However, also of interest is estimation of the variability in the effect sizes (heterogeneity), because this allows assessment of the consistency of effects across studies and estimation of the…
Workshop Advanced meta-analysis 2: Performing meta-analysis in the presence of rare events
2023 London
Chaimani, Evrenoglou
Background: Rare events are a common problem in meta-analysis, particularly for secondary and safety outcomes. When the events are rare, standard meta-analytical approaches have important limitations and may lead to biased and imprecise results. Alternative methods have been proposed in the…
Poster Alternative distributions for random effects meta-analysis model
2023 London
Panagiotopoulou, Metelli, Chaimani
Background: Random effects meta-analysis is widely used for synthesizing the studies of a systematic reviews under the assumption that the underlying study-specific treatment effects come from a common normal distribution. However, this assumption is sometimes not justifiable, such as in presence…
Oral An Evidence Ecosystem Evaluation for the Prevention and Control of Healthcare-Acquired Infections in China
2023 London
Yu, Chen
Background:
The COVID-19 pandemic has created significant challenges for healthcare, especially the increase in health-acquired infections (HAIs), which has put significant pressure on the development of social and economic policy in China. At present, the number of HAIs-related research and policy…
Poster An analytical apparatus for including art-research evidence in a systematic review
2023 London
Hannes, Siegesmund
Background: In times of crisis, art provides an outlet for many to express their feelings, emotions and experiences. We collected art-research works to answer the question of how to best sustain life on earth under pandemic lock-down conditions.
Objectives: Starting from a multimodal research…
Oral An assessment of the design-by-treatment interaction model for network meta-analysis inconsistency
2023 London
Konstantinidis, Rodrigues, Tsokani, White, Higgins, Schwarzer, Mavridis, Tricco, Veroniki
Background: Network meta-analysis (NMA) is a powerful method that simultaneously synthesizes evidence from studies addressing the same clinical question comparing multiple interventions. The method allows inferences based on direct and indirect comparisons in a network. However, NMA results are…
Poster An exploration of knowledge translation in a wider audience by holding Cochrane evidence dissemination competitions via social media in China
2023 London
Li, Zhang, Suo, Shen, Hu, Wang, Jiang
Background: A lot of efforts have been made to translate Cochrane abstracts and plain language summaries (PLSs) in order to get the high-quality evidence available to a wider audience. However, failure of getting people with less or no expertise to understand the research itself is another barrier…
Oral An open competition involving thousands of competitors failed to construct useful search filters for new diagnostic test accuracy systematic reviews
2023 London
Kataoka, Taito, Yamamoto, So, Tsutsumi, Anan, Banno, Tsujimoto, Wada, Sagami, Tsujimoto, Nihashi, Takeuchi, Terasawa, Iguchi, Kumasawa, Kasuga, 999, Yamabe, Furukawa
Background:
No abstract classifier can be used for new diagnostic test accuracy (DTA) systematic reviews to select primary DTA study abstracts from database searches.
Objectives:
Our goal with the FILtering of diagnostic Test accuracy studies (FILTER) Challenge was to develop machine learning…
Poster An overview of Cochrane reviews of predictive, prognostic or prognostic modelling studies
2023 London
Posadzki
Background: Prognostic or prognostic modelling studies are developed to give accurate and discriminating predictions about the likelihood of a future outcome in individuals with a given disease or health condition and are increasingly being used in evidence-based medicine of the XXI century.…
Poster An unusual diagnostic test accuracy review: challenges in study identification, data extraction and quality assessment
2023 London
Probyn, Sguassero, Smith, Leeflang, Bergman, Buckley, Chaplin, Cogo, Cohen, Ford, Henschke, Orrell, Petkovic, Sebastianski, Garner, Hine, Villanueva
Background:
This was a joint project of Cochrane Response and Cochrane Infectious Diseases Group. The aim of the review was to determine the accuracy of simple measures of antiretroviral therapy (ART) adherence for detecting non-suppressed viral load in people with HIV that could be utilized in…
Poster Analysis of continuous outcomes when a large proportion of the data are zeroes
2023 London
Sandercock, Geneen
Background:
Continuous outcomes are not straightforward to analyse if there are a large proportion of zeroes, as frequently occurs with outcomes such as volume of blood transfused for conditions for which blood transfusion is not always necessary. Should we analyse volume per person randomised (…
Oral Analysis of the proportion, role, function, and reporting quality of patient and public involvement (PPI) in systematic reviews and meta-analyses: A cross-sectional study
2023 London
Zhou, Wang, Li, Chen
Background:
Patient and public involvement (PPI) is essential to guarantee that systematic reviews are pertinent and significant to those impacted by a health condition and to those using systematic reviews to guide health policy or practice. Therefore, the BMJ issued a new policy requiring that…
Poster Application of QUADAS-C and GRADE in a Cochrane DTA Review: Comparison of lipoarabinomannan assays for tuberculosis in adults living with HIV
2023 London
Yang, Bjerrum, Kohli, Schiller, Nathavitharana, Denkinger, Steingart, Leeflang, Zwerling, Shah
Background: The WHO recommends the urine lipoarabinomannan assay Determine™ TB LAM Ag (Determine-LAM) to help diagnose tuberculosis in people living with HIV. A new assay, SILVAMP TB LAM (SILVAMP-LAM)*, may serve as a replacement test for Determine-LAM. Two recently developed methods allow…
Oral Applying GRADE-CERQual to interpretive review findings: Reflections from a Cochrane meta-ethnography on childhood vaccination acceptance
2023 London
Cooper, Leon, Schmidt, Swartz, Wiysonge, Colvin
Background:
GRADE-CERQual (Confidence in the Evidence from Reviews of Qualitative research) was developed to support the increasing use of review findings from qualitative evidence syntheses within policy and decision-making. To date, the approach has mainly been applied to aggregative synthesis…