Cochrane and MAGIC breaking down silos in a digital and trustworthy evidence ecosystem: results from pilot-studies on stroke, kidney diseases, musculoskeletal complaints and oral health

Tags: Oral
Vandvik P1, Brandt L2, Mavergames C3, Agoritsas T4, Elliott J5, Buchbinder R6, Craig J7, Carrasco-Labra A8, Clarkson J9, Hill K10, Tonelli M11, Guyatt G12
1Norwegian Institute of Public Health, 2MAGIC, 3Cochrane, 4University Hospitals Geneva, 5Monash University, 6Monash University and Caprini University, 7Sydney University, 8American Dental Association, 9University of Dundee, 10Australian Stroke Foundation, 11University of Calgary, 12McMaster University

Background: Cochrane has invested in the evidence ecosystem through the linked data project and recently a partnership with the MAGIC foundation. In a set of pilot projects we jointly explore innovations in sharing work and data across evidence synthesis and dissemination, through linking Cochrane Review Groups (CRG) and guideline development groups, set up for downstream implementation, to result in documented increased value or reduced waste, based on practice-changing evidence.

Objectives: The partnership aims to:

1) test MAGICapp as platform for authoring, publication and dynamic updating of evidence summaries in Cochrane Reviews, linked to guideline development;

2) create Living Cochrane Reviews and guideline recommendations;

3) disseminate evidence from Cochrane Reviews through guidelines and decision aids, ready for implementation and evaluation of impact on patient care.

Methods: Figure 1 visualises the Digital and Trustworthy Evidence Ecosystem. CRGs for stroke, kidney diseases, musculoskeletal complaints (MSK) and oral health are invited to use MAGICapp to create evidence summaries. Affiliated guideline organisations (Australian Stroke Foundation, KDIGO, American Dental Association) will use these evidence summaries to create recommendations according to standards for trustworthy guidelines. For MSK an evidence-based medicine textbook organisation in Australia (Therapeutic Guidelines) will develop the recommendations, following a living systematic review from the MSK CRG. Selected practices will be identified for implementation of recommendations, followed by evaluation of impact on delivered care and patient-important outcomes, with new evidence to be produced as needed to feed the loop.

Results: We will present results from the pilots, including barriers and facilitators for use of MAGICapp, the creation of living reviews and recommendations and plans for active implementation and evaluation of delivered care for the selected topics.

Conclusions: The Evidence Ecosystem pilots will exemplify opportunities for Cochrane Reviews to close the loop between new evidence and improved care but also remaining challenges.

Patient or healthcare consumer involvement: The evidence ecosystem project has a specific focus on how to involve patients and citizens at each step, from evidence production through evidence synthesis to better care.