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Displaying 241 - 260 of 551 records Index

Oral Factors influencing community engagement in infectious disease clinical trials in Africa: findings from a qualitative evidence synthesis and stakeholder interviews

2024 Prague [Global Evidence Summit]
Colvin, Schmidt, Spath, van Pinxteren, Wright
Background Community engagement (CE) is increasingly recognized as foundational to ethical and scientifically rigorous clinical research involving human participants. However, there is uncertainty about what CE entails, and there are critiques that CE is not systematically and meaningfully embedded…

Oral Feasibility of a "one-product" guideline for health and social care professionals and members of the public

2024 Prague [Global Evidence Summit]
James, Stein
Background The Scottish Intercollegiate Guidelines Network (SIGN) develop clinical guidelines and translate the recommendations into separate plain-language versions for members of the public. While gaining feedback on use of our guideline on perinatal mental health conditions, we discovered…

Oral Feeding the high-risk newborn and supplementation - A systematic review

2024 Prague [Global Evidence Summit]
Azhar, Yasin, Hanif, Bughio, Das, Bhutta
Introduction Preterm and LBW infants are at an increased risk of morbidity and mortality, with more than 80% of all newborn deaths occurring in the Low and Lower Middle Income Countries (LICs and LMICs). Given the increased vulnerability and higher nutritional needs of these infants, optimizing…

Oral Fit-for-use evidence on benefits and harms when adoloping guidelines: the complexities of decisions to use, update, or do new reviews

2024 Prague [Global Evidence Summit]
Brand, Durao, Blose, Chibuzor, Chipojola, Effa, Gordon, Kredo, Mbeye, McCaul, Mthethwa, Visser, Naude
Background Reducing research waste and improving efficiency in guideline development are important in resource-constrained settings. The Global Evidence, Local Adaptation (GELA) project used GRADE-ADOLOPMENT to develop locally relevant guidelines for child health in Malawi, Nigeria, and South…

Oral Five aspects of research waste: a scoping review

2024 Prague [Global Evidence Summit]
Rosengaard
Background: The number of published journal articles has grown exponentially during the last 50 years, which may have led to some wasteful research. The extent of research waste remains uncertain, but 85% of research has been suggested to be wasted. Moreover, the terminology associated with…

Oral Food environment framework in low- and middle-income countries: A qualitative systematic review

2024 Prague [Global Evidence Summit]
Gupta
Background: Food environments have been defined more comprehensively in the last two decades. However, there are major gaps in our understanding of food environments in low- and middle-income countries (LMICs) that are transforming because of dynamic, differential, and complex local social and…

Oral Formulation an implementation research on the prevention of central line-associated bloodstream infection in PICU using the i-PARIHS framework：a pre-post study

2024 Prague [Global Evidence Summit]
Wang, ZHOU
"Background: Central venous catheters (CVCs) are widespread application during the treatment of critically ill patients. Central line-associated bloodstream infection (CLABSI) is one of its most serious complications. Although evidence-based practices for the prevention of CLABSI have been…

Oral Framework to improve the uptake of evidence in health policymaking in the World Health Organization South-East Asia Region

2024 Prague [Global Evidence Summit]
Manju, Moyana, Pathmeswaran
Globally, there is recognition that using research evidence in health policymaking can strengthen health systems and accelerate progress toward achieving the Sustainable Development Goals. Moreover, the COVID-19 pandemic increased demands for evidence to inform policy and enhance accountability and…

Oral From Evidence to Recommendation: Bridging Perspectives and Achieving Consensus in Clinical Practice Guidelines Development

2024 Prague [Global Evidence Summit]
Ivlev, Totten, Chou, Uhl
Background: Clinical guideline development depends on expert panels tasked with evaluating evidence and forming consensus on recommendations. This process faces challenges from differing perspectives, values, and evidence interpretation. Conscious or unconscious biases underscore the difficulty in…

Oral From global to local: transferability of evidence to inform policy about women’s economic empowerment in Brazil

2024 Prague [Global Evidence Summit]
Dias, Gubert
Background Tackling gender-based segregation in the labor market is essential for promoting women’s economic empowerment. In Brazil, occupational gendered segregation is still significant and has consequences that reinforce both economic and social inequalities. This research presents a case of…

Oral From rote learning to best practices: can pedagogic audits and feedback improve teachers' compliance to evidence and boost learning outcomes?

2024 Prague [Global Evidence Summit]
Djibeldi, Lum, Monday Osagie, Pambe, Zabeirou
Background: Learning outcomes within Sub-Saharan Africa are particularly dire, with 9/10 children unable to read with comprehension by 10 years compared to 1/10 children in high-income countries. To improve the quality of education, a rigorous focus on teaching and learning, particularly on…

Oral From testing to development: building and assessing a large language model for public health evidence synthesis

2024 Prague [Global Evidence Summit]
Simmons, Fuller, Woolnough, Harris, Evans, Duval
Background: Recent global health challenges, such as the COVID-19 pandemic, have underscored the need for rapid evidence synthesis to support public health decision-making. Preliminary testing of data extraction with Large Language Models (LLMs) like ChatGPT has demonstrated promising capabilities…

Oral From water security to gender and tax: how facilitated learning influenced UK government decision-making

2024 Prague [Global Evidence Summit]
Georgalakis, Howard, O'Donovan-Iland
Background: The Knowledge, Evidence and Learning for Development (K4D) program (2016-2022) aimed to improve the impact of UK government development policy and programs and produced more than 1200 rapid evidence reviews and 55 emerging issue reports and designed 45 in-depth learning journeys. K4D’s…

Oral GELA applied GRADE-ADOLOPMENT for priority national child health guidelines in South Africa, Malawi, and Nigeria: what did we learn?

2024 Prague [Global Evidence Summit]
Brand, Effa, Kredo, Masingi Mbeye, McCaul, Naude
Background The Global Evidence, Local Adaptation (GELA) project aims to develop evidence-informed guideline recommendations for newborn and young child health in Malawi, Nigeria, and South Africa, underpinned by the GRADE-ADOLOPMENT approach. Applying a state-of-the-art Evidence-to-Decision (EtD)…

Oral GIN-McMaster Guideline Development Checklist extension for engagement

2024 Prague [Global Evidence Summit]
Akl, Concannon, Khabsa, Lytvyn, Magwood, Petkovic, Schunemann, Tugwell, Welch
Background: Guidelines shape clinical, public health, and health system decision-making. Trustworthy guidelines are systematically developed documents that include actionable statements based on evidence and a formal, structured, and transparent decision process. The Guidelines International…

Oral GRADE Good Practice Statements – a time to say “goodbye”?

2024 Prague [Global Evidence Summit]
Norris
Background Guidelines include a variety of types of normative statements (NSs) concerning interventions. “Recommendations” are based on 1 or more systematic reviews (SRs) of research evidence. Guidelines may also include other types of NSs such as GRADE Good Practice Statements (GPSs), which are…

Oral GRADE Guidance 39: Using GRADE-ADOLOPMENT to adopt, adapt, or create contextualized recommendations from source guidelines and evidence syntheses

2024 Prague [Global Evidence Summit]
Akl, Darzi, Klugar, Klugarova, Lotfi, Schunemann
Background: The GRADE-ADOLOPMENT methodology has been widely used to adopt, adapt, or de novo develop recommendations from existing or new guideline and evidence synthesis efforts. This guidance refines the operationalization for applying GRADE-ADOLOPMENT. Methods: Through iterative discussions,…

Oral Global evidence and local adaptation: lessons from Malawi of a guideline development and adaptation process

2024 Prague [Global Evidence Summit]
Besnier, Brand, Chipojola, Glenton, Kredo, Kunje, Lakudzala, Lewin, Mbeye, Mpando, Munabi Babigumira, Naude
Introduction Guidelines that are based on the best available evidence are key to strengthening health systems and enhancing equitable health access. However, a guideline development process can be complex and resource intensive. The Global Evidence, Local Adaptation (GELA) project supports…

Oral Global opportunities for computable evidence: changing how NICE develops healthcare guidelines

2024 Prague [Global Evidence Summit]
Friedman, Rowark, Scott, Wyatt
Background The strategy of the UK National Institute for Health and Care Excellence (NICE) for 2021-2026 set out objectives for new methods of guideline development that move toward “recommendations produced in an interactive, digitalised format.” To support these objectives, NICE formed a Content…

Oral Global overview of suicidal behavior and risk factors during the COVID-19 pandemic: a scoping review

2024 Prague [Global Evidence Summit]
Tsai, sriyani konara mudiyanselage, Tsai, Yang, Lu, Ko
Background: The COVID-19 pandemic has significantly impacted global mental health, with potential implications for suicidal behaviors. Understanding these patterns is essential for developing effective interventions and management strategies. Objective: The aim of this study is to offer a global…