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Poster Methodological quality of systematic reviews on physical exercise for breast cancer patients. Meta-epidemiological study.
Bomfim, de Barros, de Menezes, Crizol, Colovati, Martimbianco
Background: Several clinical trials have been published in recent years to investigate the probable benefits of physical exercise for women with breast cancer. It is necessary to carry out systematic reviews using a rigorous methodology to ensure that decision-making is based on the best available…
Poster INDEXING OF NIGERIAN BIOMEDICAL JOURNALS AND INFORMATION RETRIEVAL
Chibuzor, Ndukwu, Arikpo, Otonkue, Esu, Effa
Background:
Journals are indexed to promote accessibility and visibility of research output. It is unclear the extent to which Nigerian Biomedical Journals are indexed online. This could limit the visibility of research that could contribute to the advancement of science locally and globally. In…
Poster ADAPTING CLINICAL PRACTICE GUIDELINES TO DIGITAL TOOLS: A METHODOLOGICAL STUDY
Motter, Gadenz, Leao, Riera, Caluza, Mantese, Batista, Aquino, Gonçalves, Bitencourt, Coelho, Oliveira, Brandes, Suffert, Rocha, Perius, Sperling
Background: In Brazil, the process of development and updating of the clinical guidelines for the Brazilian Unified Health System (Sistema Único de Saúde, SUS) is already well systematized by the Ministry of Health. However, implementing such guidelines within local contexts and at the point of…
Poster Methodological approaches for developing and reporting Living Evidence synthesis
Auladell-Rispau, Bendersky, Trujillo, Verdugo, Avila, Gempeler, Buchanan, Alonso, Rada, Urrutia, Rojas-Reyes
Background: Living evidence (LE) approach permits new research findings to be continually incorporated into evidence synthesis. Methods for this type of synthesis are not completely defined. The approaches currently used by the authors are unknown.
Objectives: To identify, evaluate and summarize…
Poster Core outcome set development for intervention research on snakebite in South Asia: methodological case study
Bhaumik, COS-Snakebite-South-Asia-Group
Background:
Core outcome set (COS) are a consensus-derived set of outcomes that should be minimally measured in future research or practice for a specific condition. A COS for intervention research on snakebites in South Asia was developed, and several new methodological insights were obtained.…
Oral Mapping the Maps: Methods and Uses of Evidence and Gap Maps.
Campbell, Wong, Llewellyn, Bond
Background:
Evidence and Gap Maps (EGMs) sit within a family of evidence synthesis methods that seek to address broader research questions. EGMs are a valuable tool in which a wider understanding is needed of existing research in a topic area and locating evidence gaps. They do not synthesise…
Poster Inter-rater reliability of AMSTAR-2 in a review of systematic reviews about interventions to prevent adverse events in the intensive care unit
Pantoja, Suclupe, Requeijo, Salas, Merchán, Uya, Martinez-Zapata
Background:
The AMSTAR-2 (A MeaSurement Tool to Assess systematic Reviews) is a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. With 16 items for evaluation (7 critical and 9 noncritical), the discordances are…
Poster Defining misinformation and related terms: a scoping review of the health-related literature
El Mikati, Hoteit, Harb, El Zein, Piggott , Melki, Akl, Mustafa
Background: Misinformation poses a serious challenge to clinical and policy decision-making in the health field, which relies on accurate and reliable information. The COVID-19 pandemic amplified interest in misinformation and related terms and witnessed a proliferation of definitions.
Objectives…
Oral Living Evidence to Inform Health Decisions Framework (LE-IHD): A practical interactive framework based tool to guide the incorporation of Living Evidence in the development of knowledge transfer products
Rojas-Reyes, Bendersky , Auladell-Rispau, Verdugo, Rada, Alonso-Coello, Urritia
Background: Knowledge transfer [KT] products used to inform health decisions should be based on the most current evidence. A framework based practical tool for incorporating the Living Evidence [LE] model can address this need.
Objectives: To define a framework to guide the incorporation of the…
Oral Rapid reviews, how much do they comply with Cochrane recommendations in their methodology to provide reliable evidence?
Fuentes-Aspe, Oliveros-Sepúlveda, Gutierrez-Arias, Serón-Silva
Background: During the COVID-19 pandemic, a large increase in rapid reviews (RRs) was identified. This is mainly because the design appears as an alternative to provide timely and rapid responses to emerging issues. RRs follow the method of systematic reviews, but they simplify or omit some steps…
Poster Epistemonikos Database of Randomized Trials: methods and preliminary results of a comprehensive, living database of trials
Ávila, Vergara, Vásquez, Verdugo-Paiva, Peña, Novillo, Ramos, Cantor-Cruz, Rojas, Veloso, Diaz, Bosio, Biscay, Bignon, Pinto, Silva, Cayupán, Zambrano, Jara, Nava, Garrido, Silva, Rada
Background:
The Epistemonikos Database of Systematic Reviews is the largest repository of health-related systematic reviews. It combines a systematic approach, large-scale human collaboration and diverse technologies. Recognizing the significance of randomized trials in health decision-making, we…
Oral Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) extension for living systematic reviews (LSRs)
Akl, Khabsa, Iannizzi, Piechotta, Kahale, Barker, McKenzie, Page, Skoetz
Background:
There is substantive variation in how living systematic reviews (LSRs) are reported. An extension to the current Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020 statement is needed to better address the unique aspects of LSR reporting.
Objectives:
To…
Oral Producing Cochrane reviews with multi-stakeholder synergic involvement. An experience with treatments for multiple sclerosis
Nonino, Baldin, Ridley, Minozzi, Gonzalez-Lorenzo, Schűnemann, Piggott, Saylor, Peryer, Tramacere, Foschi, Del Giovane, Filippini, Pasi, Giroldini, Rijke, Laurson-Doube
Background: Involvement of key stakeholders and evidence users in the planning and development of systematic reviews (SRs) improve their overall quality and usefulness, facilitate uptake and reduce health inequities. Synergy among entities influencing or making decisions in health is important to…
Poster How is Evidence Used in Pathology? Using Evidence Gap Maps to shine a light on existing practice and research needs.
Del Aguila Mejia, Campbell , Colling, Indave Ruiz, Cree
Background: The World Health Organization (WHO) Classification of Tumours (WCT), published as the WHO Blue Books and the Blue Books online, is the ‘gold standard’ used by pathologists, clinicians and researchers for cancer diagnosis, research, treatment and prognosis. It encompasses scientific…
Oral TRIPOD-SRMA: Reporting guideline for transparent reporting of systematic reviews and meta-analyses of prediction model studies
Snell, Levis, Damen, Dhiman, Debray, Hooft, Reitsma, Moons, Collins, Riley
Background:
Systematic reviews (SRs) and meta-analyses (MAs) of prediction model studies range in breadth and can aim to identify, appraise and summarise the evidence about existing models and their predictive performance. They differ in many important ways from SRs of intervention studies.…
Poster Prevention and control of surgical site infection: preliminary results of a best practice implementation project
Fernandes, Coelho, Afonso, Martins, Sampaio, Felizardo, Cardoso
Background: Surgical site infections (SSIs) can cause significant harm to the patient, such as increased length of stay, readmissions, suffering or even death. Depending on several factors, SSIs can occur in approximately 2%-5% of inpatient surgeries and, for certain types such as abdominal surgery…
Oral Challenges and potential solutions for reporting findings from multicomponent meta-regression models in GRADE summary of findings tables
Konnyu, Trikalinos, Yogasingam, Ivers, Grimshaw
Background: We recently completed a Cochrane review of diabetes quality improvement (QI) trials that aimed to identify promising QI strategies (or combinations of strategies) to deploy in practice or examine in future research. We coded interventions according to the presence of absence of 12 QI…
Oral Impact of Grading of Recommendations, Assessment, Development and Evaluation (GRADE) on conclusions of dentistry systematic reviews
Azab, Ibrahim, Chu, Li, Modi, Wang, Hong, Abumustafa, Yan, Park, Miroshnychenko, Brignardello-Petersen
Background:
The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach assesses certainty of evidence (CoE) in a systematic review (SR) and facilitates drawing appropriate conclusions that consider limitations of the evidence. However, GRADE is not widely used in…
Poster Methodological assessment of cost-effectiveness studies of treatment with biologicals of severe asthma: a systematic review [MeCoBiA].
De la Torre Pérez, Quirland Lazo, Canelo, Alonso Coello
Background: There has been a growth in the number of economic evaluations in the literature, reporting important differences in their designs and results for a particular health technology. Previous research has shown systematic differences among incremental cost-effectiveness ratios (ICERs) and…
Poster Comparative analysis of clinical trials in psychotherapy and pharmacotherapy for treatment of depression
Helfer
Background: Extensive evidence-based literature exists on the comparative merits of talking therapies and using antidepressant medication for the treatment of depression. However, clinical research concerning psychotherapy and pharmacotherapy is often divided along disciplinary lines, and key…