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Displaying 1 - 20 of 307 Index
Oral A Bayesian approach to detect outliers in Network Meta-analysis
2020 Abstracts
Metelli , Mavridis, Chaimani
Background: Network meta-analysis (NMA) is rapidly reaching the forefront of health care research. To avoid misleading conclusions and provide valuable information for clinical decision making, NMAs need to be assessed thoroughly against potential sources of bias. A potentially major threat of the…
Oral A Living Systematic Review to Support Health Technology Assessment: The CADTH Experience
2020 Abstracts
Weeks, Kim, Lachance, Carson
Background: Living systematic reviews (LSRs)–systematic reviews that are continuously updated as new evidence becomes available–are increasingly being used to support clinical practice and guideline development. LSRs are also well suited to support health technology assessment (HTA), although to…
Oral A Model for Timely Synthesis and Sharing of Evidence to Meet Health System Decision-Maker Needs
2020 Abstracts
Tricco, Chaudhry , Zarin, Abou-Setta, Curran, Clement, Holmes, LeBlanc, Rodin, Downey, Straus
Background: The Strategy for Patient-Oriented Research (SPOR) Evidence Alliance (hereafter, the Alliance) is a pan-Canadian initiative designed to promote evidence-informed healthcare and policy that is grounded in the principles of inclusion, diversity, integrated knowledge translation, co-…
Oral A Proposal of Reporting Items for Evidence Briefs for Policy: RIGHT-EBP
2020 Abstracts
Wang, Zhang, Wu, Ma, Yang, Chen, Yang, Lavis
Background: The evidence briefs for policy (EBPs) can provide potential policy options on a specific topic for health policymakers. An increasing number of organizations (e.g. McMaster Health Forum, the World Health Organization) already developed and are developing the policy briefs on different…
Oral A Survey of Characteristics and Potential Contribution of Registered Studies for 2019 novel coronavirus disease (COVID-19)
2020 Abstracts
Yang, Shang, Tian, Xiong, Lu, Jiang, Zhang, Zhang, Jin, Jin, Zhang, Willcox, Liu
Background: The World Health Organization characterized the 2019 novel coronavirus disease (COVID-19) as a pandemic on March 11. As of March 31, 803,541 people were confirmed infected with COVID-19 in 201 countries, areas or territories with cases. As a novel coronavirus disease, there is no…
Oral A modeling approach to derive baseline risk estimates for GRADE recommendations: Concepts, development, and results of its application on a guideline.
2020 Abstracts
Morgano, Wiercioch, Anderson, Brożek, Santesso, Xie, Cuker, Nieuwlaat, Akl, Darzi, Yepes-Nuñez, Exteandia-Ikobaltzeta, Rahman, Rajasekhar, Rogers, Tikkinen, Yates, Dahm, Schünemann
Background:
Baseline risks are required to calculate absolute effect estimates, which are essential elements of evidence summaries produced for guideline panels. Systematic reviews of prognostic observational studies are scarce and the available estimates are often not directly applicable to…
Oral A new machine-learning powered tool to aid citation screening for evidence synthesis: PICOPortal
2020 Abstracts
Agai
Background:
Identifying all evidence relevant to a systematic review remains a critical yet time-consuming step in the evidence synthesis process. Machine learning methods and collaborative screening software constitute potential means of reducing the workload necessary to perform citation…
Oral A pilot to translate Cochrane Incontinence blogshots: does it sustainably help reach a more global audience?
2020 Abstracts
Johnson, Ried
Background: In 2017, Cochrane Incontinence adopted a new dissemination policy that included the production and circulation of visual products to disseminate the key evidence of its reviews, such as blogshots (a short summary of key points from a review with a picture that can be shared on social…
Oral A protocol for the practical application of human rights in World Health Organization guideline development
2020 Abstracts
Thomas, Thomas Bosco, Takawira, Peretz , Garner
Background:
Equity, rights, gender and societal (ERGS) considerations are central to achieving global health and well being as well as more equitable distribution of good health. The World Health Organization (WHO) is mandated to ensure incorporation of ERGS into its guidelines. However,…
Oral A readability assessment of Plain Language Summaries and abstracts of Cochrane Systematic Reviews published during 2019
2020 Abstracts
Meza, Perez-Bracchiglione, Franco, Garnham, Tapia-Benavente, Olguín-Sepúlveda, Urrútia, Madrid
Background:
Plain Language Summaries (PLS) of Cochrane Systematic Reviews (CSR) must be written in clear and simple language to serve a relevant aim of knowledge translation, and must be accurately summarised in a succinct and readable style, as a way to deliver the results to a broad audience.…
Oral A snapshot of the review prioritisation work conducted by the Gynaecological, Neuro-oncology and Orphan Cancers Group since 2007.
2020 Abstracts
Quinn, Jess, Grant, Tomlinson, Harrison, Platt
Background:
Setting systematic review topic priorities is vital for Cochrane Review Groups. It helps to ensure Cochrane review evidence is relevant to end-users such as clinicians, consumers, healthcare professionals and policy makers. Since 2007, the Gynaecological, Neuro-oncology and Orphan…
Oral A tool to assess Risk Of Bias In Non-randomised Studies - of Exposures (ROBINS-E)
2020 Abstracts
Morgan, Taylor, Higgins, Rooney, Thayer, Schunemann, Sterne
Background: Systematic reviews should include rigorous risk-of-bias assessments of eligible studies. Although a large majority of Cochrane reviews address the effects of interventions, there is increasing interest in systematic reviews of other types of problem. One important category is systematic…
Oral AMSTAR2 or ROBIS to teach evidence synthesis?
2020 Abstracts
Lee
Background:
Systematic reviews (SRs) are an important source of evidence that are used to inform decision making. As such, it is important that healthcare students are taught these on how to interpret, and judge the methodological quality of systematic reviews. Several tools currently exist to…
Oral Accelerating integration of emerging evidence into health care delivery: rapid reviews for learning health systems
2020 Abstracts
Hager, Jungbauer
Background: Ideally, clinical care is based on real-time, best available evidence. In reality, research findings take on average 17 years to translate into policy and practice. Developing and implementing health system guidelines using a rapid review process can reduce the time it takes to…
Oral Achieving evidence interoperability in the computer age: setting evidence on the FHIR (Fast Healthcare Interoperability Resources)
2020 Abstracts
Alper, Munn , Salas, Tristan, Brand, Lorio, Schilling
Evidence standard practice requires the use of research results to inform the computers that can add capacity for evidence-based practice by making the information from research results, standard the summarisations searchable and re-usable without labour-intensive manual screening and repetition of…
Oral Addressing interdependency of data when conducting systematic reviews and meta-analyses
2020 Abstracts
Lietz, Sieben, Sauerland
Background:
Some clinical study designs require that interdependency of data (IoD) be addressed in the reporting of study results. In self-controlled and cross-over trials, patients form part of both the intervention and control groups. In other studies, multiple disease locations are measured in…
Oral Adjusting for exposure misclassification in an individual participant data meta-analysis of observational studies
2020 Abstracts
De Jong, Campbell, Jaenisch, Gustafson, Debray
Background
A common problem in the analysis of multiple data sources, including individual participant data meta-analysis (IPD-MA), is the presence of misclassification of binary variables. Misclassification may bias estimates of parameters (including covariate effects), even when the…
Oral An evidence-informed and stakeholder co-designed physical and community mobility intervention for older adults facing health inequities: the EMBOLDEN study
2020 Abstracts
Neil-Sztramko, Teggart, Phillips, Sherifali, Fitzpatrick-Lewis, Newbold, Coletta, Alvarez, Kuspinar, Raina, Ganann
Background: Physical mobility and social participation are requisite for independence and quality of life as one ages. Barriers to mobility lead to social isolation, poor physical and mental health, all of which are precursors to frailty. To date, most mobility-enhancing interventions for older…
Oral An initiative to provide evidence-based support for judicial decision on healthcare in Brazil
2020 Abstracts
Riera, Pachito, Bagattini
Background: Between the years of 2008 and 2017, judicial demands related to healthcare increased 130% in Brazil [1]. In 2016, the 10 most expensive drugs that were legally demanded comprised 91% of the resources guaranteed for the acquisition of technologies by the Brazilian Government. In this…
Oral An international survey reveals current worldwide practice for rapid reviews (RR) of diagnostic tests
2020 Abstracts
Arevalo-Rodriguez, Steingart , Tricco, Nussbaumer-Streit, Kaunelis, Alonso-Coello, Baxter, Bossuyt, Emparanza, Zamora
BACKGROUND: Rapid reviews (RRs) have emerged as an efficient alternative to meet the demand for accelerated evidence synthesis for healthcare decision-making. In a previous scoping review, we examined the characteristics of RRs of diagnostic tests by scrutinizing repositories of Health Technology…