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Displaying 1 - 20 of 3000 records Index
Oral Living Evidence to Inform Health Decisions Framework (LE-IHD): A practical interactive framework based tool to guide the incorporation of Living Evidence in the development of knowledge transfer products
2023 London
Rojas-Reyes, Bendersky , Auladell-Rispau, Verdugo, Rada, Alonso-Coello, Urritia
Background: Knowledge transfer [KT] products used to inform health decisions should be based on the most current evidence. A framework based practical tool for incorporating the Living Evidence [LE] model can address this need.
Objectives: To define a framework to guide the incorporation of the…
Oral A call to support Cochrane's social responsibility of improving health equity - the Equity Group
2023 London
Parker, Petkovic, Pardo Pardo, Welch, Tugwell
Background:
Health equity is a moral and ethical imperative. In the 2022 Cochrane Lecture, Jimmy Volmink challenged the organization to address not only inequities raised from health interventions but also consider how to address the social determinants of health which lead to such disparities.…
Oral A comparison of different forward citation chasing tools for complementary searches for Cochrane systematic reviews
2023 London
Bracchiglione, Requeijo, Santero, Savall, Selva, Samsó, Roqué-Figuls, Escobar Liquitay, Solà
Background: Forward citation chasing, defined as the use of a citation index to retrieve references that cite a source, is currently recommended as a complement to find all possibly relevant research for systematic reviews (SRs). Recently, new tools have been developed to ease this task, but their…
Oral A critical appraisal tool for systematic reviews of patient-reported outcome measures
2023 London
Lei, Xiong, Wang, Li, Norris, Chen
Background:
Systematic reviews (SRs) of patient-reported outcome measures (PROMs) are an important way to select the appropriate PROMs. High-quality SRs can provide a comprehensive overview of the PROMs and provide evidence-based recommendations for pediatricians. However, because the risk of bias…
Oral A digital map of systematic reviews on non-pharmacological interventions to inform policy making in infectious disease control
2023 London
Wilbe Ramsay, Edebert, Palmquist Wojda, Östlund
Background: The COVID-19 pandemic accentuated the need for comprehensive evidence synthesis to guide decisions regarding infection disease control and preparedness. In Sweden, an investigator was tasked by the government with reviewing the Infection Control Act and analyzing the need for new…
Oral A living network meta-analysis of treatments for rheumatoid arthritis: Novelty at the frontier of living evidence
2023 London
Whittle, Thomas, Mujaab Kamso, Pardo Pardo, Buchbinder, Hazlewood
Background: Choosing between the many effective disease-modifying therapies (DMARDs) for rheumatoid arthritis requires timely, high-quality systematic review of the best available evidence. ‘Living’ systematic reviews fast-track evidence synthesis without compromising rigorous systematic review…
Oral A method for the rapid assessment of high-cost cancer drug indications in a hospital setting
2023 London
González-Browne, Carreño-Leiton, Muñoz-Montecinos, Maza, Lahoz, Ferrer-Rosende, Nájera-De Ferrari , Quirland-Lazo
Background:
Hospitals are usually the entry point of new technologies. Facing the challenge posed by the growing costs of cancer drugs, there is a need for healthcare providers to articulate systematic and timely formulary decision-making processes considering not only the efficacy and safety of…
Oral A novel modeling approach for producing treatment hierarchies in network meta-analysis
2023 London
Evrenoglou, Chaimani
Background:
Network meta-analysis (NMA) allows synthesising the evidence simultaneously on multiple treatments. A key output of NMA is the relative ranking of the treatments; nevertheless, it has attracted a lot of criticism. This is mainly because ranking is a very influential output and, thus,…
Oral A real-world example demonstrating the application of Cochrane guidance to ensure transparent synthesis of evidence addressing a broad policy question
2023 London
Brennan, Murano, McDonald, Turner, Synnot, Nguyen, Jones, McKenzie
Background:
Specifying questions and criteria at the level of each synthesis can enhance the transparency of reviews and help ensure that reviews address questions of importance to decision-makers. Version 6 of the Cochrane Handbook for Systematic Reviews of Interventions introduced the concept of…
Oral AHRQ Evidence-based Practice Center and NIH Pathways to Prevention programs: A decade-long partnership in closing evidence gaps
2023 London
Bañez, Niebuhr, Iyer, McNellis, Chang, Umscheid
Background: The U.S. Agency for Healthcare Research and Quality (AHRQ)’s Evidence-based Practice Center (EPC) Program produces evidence reports to inform healthcare decision-makers such as funding agencies supporting new research. The National Institutes of Health (NIH)’s Pathways to Prevention (…
Oral Abstracts of Cochrane reviews are getting longer, but this has no large impact on the reporting quality.
2023 London
Helbach, Wandscher, Pieper, Hoffmann
Background:
In our previous study on the reporting quality of abstracts according to PRISMA-A, we found that abstracts of Cochrane reviews (CRs) were better reported than non-Cochrane reviews, differed significantly in length (median length: 507 words vs. 249 words), and appeared to be getting…
Oral Adherence to PRISMA 2020 statement in non-Cochrane systematic reviews of interventions. A meta-epidemiological study
2023 London
Ivaldi, Burgos, Oltra, Escobar Liquitay, Garegnani
Background:
Evidence-based medicine (EBM) is defined as the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of patients by integrating individual clinical expertise, the best available clinical evidence, and the individual patient’s preferences…
Oral An Evidence Ecosystem Evaluation for the Prevention and Control of Healthcare-Acquired Infections in China
2023 London
Yu, Chen
Background:
The COVID-19 pandemic has created significant challenges for healthcare, especially the increase in health-acquired infections (HAIs), which has put significant pressure on the development of social and economic policy in China. At present, the number of HAIs-related research and policy…
Oral An assessment of the design-by-treatment interaction model for network meta-analysis inconsistency
2023 London
Konstantinidis, Rodrigues, Tsokani, White, Higgins, Schwarzer, Mavridis, Tricco, Veroniki
Background: Network meta-analysis (NMA) is a powerful method that simultaneously synthesizes evidence from studies addressing the same clinical question comparing multiple interventions. The method allows inferences based on direct and indirect comparisons in a network. However, NMA results are…
Oral An open competition involving thousands of competitors failed to construct useful search filters for new diagnostic test accuracy systematic reviews
2023 London
Kataoka, Taito, Yamamoto, So, Tsutsumi, Anan, Banno, Tsujimoto, Wada, Sagami, Tsujimoto, Nihashi, Takeuchi, Terasawa, Iguchi, Kumasawa, Kasuga, 999, Yamabe, Furukawa
Background:
No abstract classifier can be used for new diagnostic test accuracy (DTA) systematic reviews to select primary DTA study abstracts from database searches.
Objectives:
Our goal with the FILtering of diagnostic Test accuracy studies (FILTER) Challenge was to develop machine learning…
Oral Analysis of the proportion, role, function, and reporting quality of patient and public involvement (PPI) in systematic reviews and meta-analyses: A cross-sectional study
2023 London
Zhou, Wang, Li, Chen
Background:
Patient and public involvement (PPI) is essential to guarantee that systematic reviews are pertinent and significant to those impacted by a health condition and to those using systematic reviews to guide health policy or practice. Therefore, the BMJ issued a new policy requiring that…
Oral Applying GRADE-CERQual to interpretive review findings: Reflections from a Cochrane meta-ethnography on childhood vaccination acceptance
2023 London
Cooper, Leon, Schmidt, Swartz, Wiysonge, Colvin
Background:
GRADE-CERQual (Confidence in the Evidence from Reviews of Qualitative research) was developed to support the increasing use of review findings from qualitative evidence syntheses within policy and decision-making. To date, the approach has mainly been applied to aggregative synthesis…
Oral Archie Cochrane's Second E - the creation of Value based Healthcare
2023 London
Gray
Every country on earth is now facing a resource crisis that will not be resolved simply by focusing more on effectiveness; a new paradigm is required - value based healthcare (VBHC).
The EU definition of VBHC is now adopted globally, except in the USA which is not committed to universal healthcare…
Oral Are there missing randomized trials in Cochrane systematic reviews and what is their impact on the results?: A methodological study
2023 London
Bravo-Soto, Montalva-Romero, Brignardello-Petersen
Background:
Owing to reproducibility, reliability and exhaustiveness, systematic reviews (SRs) are considered the best type of evidence synthesis to inform decision-making, which is why the development of SRs increases every year. Because of this, it is possible to find several SRs answering the…
Oral Assessment of trustworthiness has a significant impact on conclusions of Cochrane reviews
2023 London
Alfirevic, Weeks, Cuthbert
Background:
There is increasing concern that a significant proportion of randomised trials included in Cochrane reviews may not be trustworthy. Applying a Trustworthiness Screening Tool (TST) has already had a clinically important effect on several reviews published by the Cochrane Pregnancy and…