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Workshop Finding, critically appraising, and using a core outcome set (COS) to inform your systematic review
2023 London
Williamson, Barrington, Saldanha, Smith, Gorst
Background:
A core outcome set (COS) is an agreed standardised set of outcomes that should be measured and reported, as a minimum, in all clinical trials in a specific health condition. This would allow research to be compared and combined, ensuring all studies contribute usable information for the…
Workshop First do no harm: how can systematic reviewers do justice to harms? Deciding which harms to search for and how
2023 London
Golder, Vohra, Kwong
Background: Any intervention that can have an effect has the potential to have an adverse effect. All systematic reviews of interventions should at least consider the harms of that intervention. Harms are important to patients, impacting on morbidity and mortality.
There are many differences (as…
Workshop Forward together: new ways to participate in Cochrane
2023 London
Shackleton, Deppe, Noel-Storr, Morley
Background: Cochrane has developed many new ways to get involved, which go beyond authoring reviews. These include Cochrane Crowd, Cochrane Engage, translations, and consumer engagement. These initiatives are part of Cochrane’s Membership Project that seeks to broaden our community by giving a…
Workshop GRADE target of certainty rating and implications for judgements regarding imprecision
2023 London
Zeng, Guyatt
Objectives: This workshop will introduce participants to the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) guidance on choosing targets of certainty of evidence and its implication on rating imprecision of evidence.
Description: We will give a presentation to start…
Workshop Health Equity: Implications for Systematic Reviews
2023 London
Welch, Magwood, Tomlinson, Spiga
Background: This is a core training session from a Cochrane Methods Group.
The Cochrane Handbook for Systematic Reviews of Interventions includes a chapter on equity and specific populations. A Cochrane Interactive Learning module has been developed to accompany this chapter. This workshop aims…
Workshop How to author, publish, and dynamically update digital and trustworthy living evidence summaries, guidelines, and decision aids using MAGICapp
2023 London
Lytvyn, Zeraatkar, Vandvik, Agarwal
Background: There is an increasing emphasis on using living evidence to inform decision-making; however, creating living guidelines and decision aids is challenging. MAGICapp (www.magicapp.org) is an open-access software for evidence users, synthesizers, guideline developers, and proponents of…
Workshop How to do a rapid review – updated methods guidance
2023 London
Nussbaumer-Streit, Griebler, Devane
Background: Having quick access to systematically produced evidence syntheses is crucial in addressing urgent health questions. The Cochrane Rapid Review Methods Group (RRMG) has published interim guidance to facilitate the conduct of Rapid Reviews (RR) both within Cochrane and beyond (1). This…
Workshop How to incorporate information on funding and conflicts of interest in trials when conducting a Cochrane Review: the TACIT tool
2023 London
Lundh, Hróbjartsson, Boutron, Stewart
Background: Industry funding and trial researchers’ financial conflicts of interest are common in clinical trials and are associated with favourable trial conclusions and seemingly greater treatment effects. Information on funding and conflicts of interest is therefore considered important when…
Workshop How to plan and implement synthesis questions (part 1): using the InSynQ checklist and guide for question development
2023 London
Brennan, McKenzie, Cumpston, Flemyng, Ryan
Background:
This is the first of a two-part workshop. This session introduces the InSynQ (Intervention Synthesis Questions) checklist and guide which aims to facilitate the development and reporting of the questions addressed in systematic reviews. The concept of defining a review ‘question’ (the…
Workshop How to plan and implement synthesis questions (part 2): Implementing PICO in RevMan to streamline data extraction and analyses
2023 London
Flemyng, Van Valkenhoef, Sambunjak, Brennan, McKenzie, Cumpston, Arevalo-Rodriguez, Hall
Participants will need to bring their own laptop.
Background:
This is the second of a two-part workshop. Defining your review ‘question’ (the objective) and developing criteria for including studies in the review using the PICO framework is a fundamental step in a systematic review. As well as…
Workshop How to use and evaluate OpenAlex tools for efficient automated updating of systematic reviews and maps in EPPI-Reviewer
2023 London
Shemilt, Thomas, Graziosi, Tenti
Background: Keeping on top of new evidence is a perennial challenge. Systematic reviews can quickly become out of date, and maintaining surveillance of new evidence can be resource intensive and costly. For example, identifying new eligible studies for updating systematic reviews and maps of…
Workshop Identifying who benefits most from treatments: How to analyse, present and interpret interactions and subgroup effects in meta-analysis
2023 London
Fisher, Godolphin, White, Tierney
Background: Researchers often wish to identify which individuals benefit more (or less) from interventions; this idea underpins the concept of stratified medicine. As single studies are typically underpowered for exploring whether participant characteristics determine an individual’s response to…
Workshop If, when and how to sample primary studies for inclusion in a qualitative evidence synthesis
2023 London
Ames, Noyes, Sutcliffe, Thomas, Houghton, Pantoja, Harden, Booth, Garside, France, Flemming
Background:
Too much data can threaten the quality of a data synthesis in a qualitative evidence synthesis (QES), and too little can limit transferability across multiple contexts. As a QES seeks to provide an interpretation of the evidence, it is not essential to identify and include every…
Workshop Impacts of climate change on health and health systems: Producing evidence syntheses to support decision-making
2023 London
Thomson, Delgado-Figueroa, Bhaumik, Cumpston, Heyn, Metzendorf, Piechotta, Skoetz, Wieland, Alcaraz-Sanchez, Ebi, Tong, Parker, O'Neill
Background
The climate emergency is a pressing threat to human health and health systems. Members of the Cochrane community must bring our evidence synthesis expertise to the work of supporting effective decision making to adapt to or mitigate its impacts. Because of the multi-level and systemic…
Workshop Integrating the findings of a qualitative evidence synthesis (QES) with the findings of a review of intervention effects
2023 London
Sutcliffe, Noyes, Harden, Ames, Houghton, Thomas, Pantoja, Garside, Booth, France , Flemming
QMIG Methods Workshop
Background: Methods for qualitative evidence synthesis (QES)—a systematic review method for bringing together qualitative studies—are now well established, and decision-makers are able to access rigorous QES on issues such as patient experiences and contextual factors…
Workshop Interpreting systematic review findings
2023 London
Sguassero, Villanueva, Sebastianski, Probyn
Background: Systematic reviews are considered the gold standard of evidence for health professionals and are increasingly used to support decision-making in health care. Understanding review results is of paramount importance in translating research evidence into clinical practice. Critical…
Workshop Introducing INSPECT-SR: a tool for detecting problematic randomised controlled trials in health systematic reviews
2023 London
Wilkinson, Heal, Sydenham, O'Connell, Richardson, Choi, Bero, Kirkham
Background:
There is a growing awareness about the problem posed by untrustworthy randomized controlled trials (RCTs) in systematic reviews. It appears that some RCTs have been partially or entirely fabricated. We call trials subject to serious research integrity issues “problematic studies”,…
Workshop Introduction to analysis and meta-analysis of interrupted time series studies
2023 London
Korevaar, Turner, McKenzie, Forbes, Karahalios, Taljaard
Background:
Interrupted Time Series (ITS) studies are commonly used to evaluate public health and policy interventions when randomisation is impractical or infeasible; for example, examining the effects of mass media campaigns on the use of methamphetamine among young adults. In an ITS study,…
Workshop Introduction to meta-analysis 1: meta-analysis of binary and continuous outcomes
2023 London
Veroniki, Tudur Smith, McKenzie
Background: A core component of many systematic reviews is meta-analysis, which is a method for statistically combining results across studies. Meta-analysis results often underpin healthcare decision-making. Most commonly, meta-analysis of binary or continuous outcomes are undertaken. Many issues…
Workshop Introduction to meta-analysis 2: dealing with heterogeneity
2023 London
Simmonds, Tsokani
Background:
The studies in a meta-analysis may vary in their included populations, how the intervention of interest was used, how outcomes were assessed, and in study design and conduct. This variability in study properties may lead to variability in the outcomes across studies. This variability…