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Displaying 21 - 40 of 528 records Index
Oral Application of Artificial intelligence in the postoperative of knee arthroplasty: a meta-analysis and systematic review
2024 Prague [Global Evidence Summit]
Zhang
Backgrounds: Artificial intelligence is an emerging and powerful technology with growing use in orthopedics. The global morbidity of total knee arthroplasty is increasing.
Objectives: This systematic review investigated the application of artificial intelligence in periprosthetic of knee joint.…
Oral Applying Subpopulation Treatment Effect Pattern Plot (STEPP) method to optimize subgroup analysis in clinical trials
2024 Prague [Global Evidence Summit]
Li, Li
Background: Subgroup analysis is a commonly used method to study whether treatment effects differ based on different covariates.
Objectives: This study aimed to introduce the concepts, advantages, and subpopulation delineation methods of the Subpopulation Treatment Effect Pattern Plot (STEPP) and…
Oral Applying an Algorithm for Incorporating Economic Evidence into Clinical Practice Guidelines: the Spanish Guideline for Management of Chronic Non-Cancer Pain
2024 Prague [Global Evidence Summit]
Moler Zapata, Gavín-Benavent, Pérez-García, de Tomás-Mateo, Bono-Vega, Isern de Val
"Background
Many international health authorities have requested that economic evidence (EE) plays a more prominent role in the development of Clinical Practice Guidelines (CPG). In Spain, due to the lack of methodological guidance, there is wide variation in how EE is incorporated in the…
Oral Applying an equity framework to assess race-aware recommendations in clinical guidelines
2024 Prague [Global Evidence Summit]
Chang, Robbins, Wu
Background: Some guidelines include special considerations for those in certain racial/ethnic groups, which may be based on evidence about disparities. Medical practice has moved toward an understanding that race is a social rather than a biological construct. However, clinicians and guideline…
Oral Applying nationwide public engagement in guideline prioritization and development of recommendations
2024 Prague [Global Evidence Summit]
Brozek, Kapil, Khoshroo, Lotfi, Motilall, Nieuwlaat, Pardo Pardo, Raja, Santesso, Schünemann, Solo, Valavil Punnapuzha, Wiercioch, Yuan
Background: Given the wide-reaching impact of post–COVID-19 condition (PCC), health guidelines addressing PCC must ensure relevance for the target audience. For the Canadian Guidelines for Post COVID-19 Condition (CAN-PCC), intended to be applicable across all Canadian healthcare settings, we…
Oral Applying the framework for actionable statements to COVID-19 guidelines
2024 Prague [Global Evidence Summit]
Akl, Alonso Coello, Lotfi, Santesso, Schünemann
Introduction
We developed a framework to characterize actionable statements in guidelines. These actionable statements are formal recommendations, good practice statements (GPSs), research-only recommendations, implementation considerations, tools and tips, and informal recommendations. Informal…
Oral Appropriate use of the label "systematic review" according to a novel definition in a sample of recently published papers
2024 Prague [Global Evidence Summit]
Arienti, Lazzarini, Minozzi, Pieper, Puljak
Background: Systematic reviews (SRs) are considered the highest level in the hierarchy of evidence in evidence-based medicine. In recent years, the number of published SRs hugely increased. However, there may be papers labeled as SRs that are not SRs, and this may create confusion in clinicians and…
Oral Are we managing the influx of living systematic reviews? "Behemoths" and "side quests"
2024 Prague [Global Evidence Summit]
Akl, Cooper, Freeman, Kahale, Khamis, Modha, Nevill, O'Mahony, Sharifan, Sharifan, Sutton
BACKGROUND
To keep up with fast-paced research and avoid systematic reviews becoming out of date, many researchers utilize living systematic reviews (LSRs), in which the literature is continuously monitored and added to the analysis and updated results are published. The flurry of research activity…
Oral Artificial intelligence in evidence production: critical reflections and lessons learned
2024 Prague [Global Evidence Summit]
Akay, Macura, Nykvist
Introduction
Systematic reviews provide robust and comprehensive assessments of available evidence guiding decision-making from medicine to international development and environmental management. Nevertheless, the rapidly increasing volume and complexity of scientific literature and limitations to…
Oral Assessing GPT-3.5 Turbo’s performance in primary screening across diverse types of systematic literature reviews
2024 Prague [Global Evidence Summit]
Rathi, Malik, Behera, Kamboj
Background: The use of large language models (LLMs) is rapidly increasing in the domain of evidence synthesis. This shift is driven by the remarkable surge in available evidence and availability of advanced LLMs in recent times.
Objectives: The objective of this study was to investigate the…
Oral Assessing and building capacity for clinical guideline development in Malawi, South Africa, and Nigeria
2024 Prague [Global Evidence Summit]
Arikpo, Effa, Esu, Kallon, Lakudzala, Mbetha, McCaul, Rohwer
Background: Limited skills in clinical practice guideline (CPG) development may affect trustworthiness of CPGs. Within the Global Evidence, Local Adaptation (GELA) project, we offered various activities to guideline development groups (GDGs) and steering group (SG) members in Nigeria, Malawi, and…
Oral Assessing attitudes towards dietary fats in five countries: development and validation of Fat-related Attitude Scale (FATTS)
2024 Prague [Global Evidence Summit]
Alonso-Coello, Bała, Castro Reyes, Cruz Lopes, de Souza Serio dos Santos, Franka Žuljević, Gajdzica, Ge, Johnston, Maraj, Poklepovic, Prokop-Dorner, Wang, Warzecha, Zawisza
Background: The multitude of contemporary discourses on dietary fat could take precedence over medical advice and instead promote uninformed health choices and adherence to established dietary patterns. Understanding patient’s beliefs and practices in regard to consumption of fats could support…
Oral Assessing characteristics and outcomes of interventions designed to mitigate the effects of adverse childhood experiences: A Scoping review
2024 Prague [Global Evidence Summit]
Dominguez, Markham, Springer, Brown
Background: Adverse childhood experiences (ACEs) are traumatic and distressing events that occur under the age of 18 to a child or a child's family and social environment. Objective: The primary purpose of this study is to describe characteristics of interventions rigorously evaluated in…
Oral Assessing dementia care gaps to guide clinical guidance scoping and other implementation efforts—the Singapore experience
2024 Prague [Global Evidence Summit]
Ho, Kim, Li, Lim, Sun, Yang
Background: Singapore has seen rising prevalence of dementia and the associated disease burden driven by an aging population. Primary care plays a pivotal role in ensuring sustainable care delivery in the community to people with dementia and their caregivers. However, gaps and variations of…
Oral Assessing success of guideline implementation: development of a generalized tool facilitating cross-comparison and targeted improvement
2024 Prague [Global Evidence Summit]
He, Huang, Huang, Li, Wang, Yang, Yi, Zeng, Zhang, Zhang, Zou
Background: Many evidence-based clinical practice guidelines fail to translate to improvement of daily health care practice and patient health outcomes. However, benchmarking and comparison between guidelines, institutions, and regions and targeted interventions are usually not feasible due to a…
Oral Assessing the Risk of Bias in Randomised Controlled Trials with Large Language Models: A Feasibility Study
2024 Prague [Global Evidence Summit]
Lai, Ge, Talukdar, Estill
Background
Large language models (LLMs) may facilitate the labour-intensive process of systematic reviews.
Objective
To explore the feasibility and reliability of utilizing LLMs to assess risk of bias (ROB) in randomised controlled trials (RCTs).
Methods
We conducted a pilot and feasibility study…
Oral Assessing the availability, scope, and quality of stroke rehabilitation guidelines in LMICs - a systematic review of quality and scope
2024 Prague [Global Evidence Summit]
Chawla, D’souza, Demers, Gandhi, Hombali, Kamalakann, Mahmood, Montanaro, Ngeh, Sebastian, Solomon, Urimubenshi
Background: A significant amount of the stroke burden globally is borne by low- and middle-income countries (LMICs). However, efforts toward reducing the stroke burden in this context have faced immense challenges. One reason is because of the scope and quality of clinical practice guidelines (CPGs…
Oral Assessing the effectiveness of artificial intelligence tools in automating systematic reviews for cancer research: a systematic review
2024 Prague [Global Evidence Summit]
Kumar, Miranda, Saha, Su, Sussman, Yao
Background:
Systematic reviews (SRs) play a crucial role in evidence-based medicine, offering guidance to clinicians to further improve patients’ outcomes. However, the time required for completing SRs, averaging around 67.3 weeks, poses a significant challenge. A literature search, particularly in…
Oral Assessing the impact of diverse definitions of major adverse cardiac events on coronary stent study outcomes
2024 Prague [Global Evidence Summit]
Du, Jin, Liao, Lin, Long, Wang
Background: Composite end points like major adverse cardiac events (MACEs) are extensively used in coronary stent research despite varied definitions. These end points, combining safety and efficacy indicators, complicate result interpretation.
Objectives: This study evaluates the impact of MACE…
Oral Assessment of Soil-Transmitted Helminths Among School-Aged Children (5-18 Years) in Low- to Middle-Income Nations: A Systematic Review and Meta-Analysis
2024 Prague [Global Evidence Summit]
Kanungo, Palo, Kshatri, Agrawal, Pattnaik, Mandal, BHATTACHARYA, Pati, Pati
Background: The Global Burden of Disease (GBD) 2019 report revealed alarming statistics regarding soil-transmitted helminths (STHs), with 1.5 million disability-adjusted life years (DALYs) lost due to STH-related issues, while a staggering 5.9 million individuals remain susceptible to STH…