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Displaying 1 - 20 of 80 records Index
Poster A World Wide Web interface for the UKCCCR Register Of Cancer Trials
1998 Baltimore
Brown, Grosse, Jenkin, Stewart, Fayers
Introduction: The UKCCCR Register of Cancer Trials is a database of United Kingdom Randomised Controlled Trials (RCTs) in cancer. The UKCCCR Register provides information for those considering participation in RCTs, helps funding bodies assess the relevance of proposals for new trials and…
Poster A challenge to accepted wisdom: systematic review of 35 Years of cholera vaccine trials
1998 Baltimore
Graves, Deeks, Demicheli, Pratt, Jefferson
Cholera killed whole-cell (KWC) vaccines have been discouraged since the 1970s in either endemic or epidemic areas on the grounds that they have low efficacy or short duration of efficacy (3-6 months), require multiple doses, and are less effective in children under five than in adults. Significant…
Poster A comparison of checked versus unchecked individual patient data (IPD)
1998 Baltimore
Burdett, Stewart
Introduction/Objectives: IPD meta-analyses (MAs) of randomised controlled trials (RCTs) usually involve detailed data checking. This can be done at different levels, from simply finding and querying missing or inconsistent data, to detailed investigation of the integrity of the randomisation and…
Poster A multifile search of five bibliographic databases for stroke trials
1998 Baltimore
Thomas, Gubitz, Mclnnes, Krabshuis, Counsell
Introduction/Objective: Electronic searching of the many available bibliographic databases is an important means of trial identification, offering quick access to many thousands of references. However, such searching is time consuming and can be expensive: complex database-specific searches need to…
Poster A pilot project to create partnerships between academic and professional organizations to produce and disseminate systematic reviews
1998 Baltimore
Hayward, Hammond, Hebert
Introduction/Objective: In 1997, the Dissemination Program of the Alberta Heritage Foundation for Medical Research in Edmonton, Canada, initiated a project to produce and disseminate systematic reviews in partnership with three health professional associations, a consumers' association and…
Poster A systematic review of magnesium sulfate in the treatment of acute exacerbations of asthma
1998 Baltimore
Rowe, Bretzlaff, Bourdon, Bota, Camargo
Introduction/Objective: To determine the effect of intravenous magnesium sulfate for the treatment of patients with acute exacerbations of asthma managed in the emergency department.
Methods: Computerised searches were conducted using the Cochrane Airways Review Group "Asthmi and Wheez"…
Poster A systematic review of nedocromil sodium in the prophylactic treatment of exercise-induced bronchoconstriction
1998 Baltimore
Spooner, Saunders, Rowe
Introduction/Objective: To assess the effectiveness and safety of using a single dose of nedocromil sodium (NCS) to prevent exercise-induced bronchoconstriction (EIB).
Methods: Computerised searches were conducted using the Cochrane Airways Review Group RCT register, Current Contents, and the CC…
Poster A systematic review of the quality of homeopathic clinical trials
1998 Baltimore
Jonas, Shasha, Anderson, Lyons
Introduction/Objective: To review the quality of clinical trial research in homeopathy and identify the extent of threats to validity of causal interpretations in these trials. In addition, we compared the type and extent of these threats to validity to research on conventional therapies.
Methods…
Poster A systematic review on the impact of mass media on health services utilisation
1998 Baltimore
Grilli, Freemantle, Minozzi, Domenighetti, Finer
Introduction/Objective: To review the available evidence on the effect of mass media (radio, TV, newspapers, magazines, leaflets, posters and pamphlets) on health services utilisation.
Methods: Unrestricted systematic literature search of experimental and rigorous quasi experimental (interrupted…
Poster Alendronate for prevention and treatment of postmenopausal osteoporosis
1998 Baltimore
Cranney, Welch, Coyle, Adachi, Tugwell, Wells, Otten, Shea, Berthelot, Wolfson, Flanagan
Introduction/Objective: We conducted a Cochrane systematic review to determine the efficacy of alendronate therapy at preventing bone loss and fractures in postmenopausal women. These results are being incorporated into a cost-effectiveness analysis of alendronate compared to hormone replacement…
Poster An electronic data repository of randomized controlled trials for the treatment of depressive disorders
1998 Baltimore
Chiquette, Aguilar, Williams, Mulrow, Cornell
Introduction: Systematic reviews depend on a comprehensive data collection of the primary studies. Since multiple reviews in the same field may use data from similar sets of trials, a computerized database of trial summaries would minimize duplication of effort and facilitate timely reviews and…
Poster An evaluation of interventions to reduce the use of tobacco products
1998 Baltimore
Honkins, Briss, Pechacek, Glynn, Fielding
Introduction/Objectives: A national, independent, non-federal organization, the Task Force on Community Preventive Services, is systematically reviewing published evidence on the effectiveness of population-based interventions to reduce the consumption of tobacco products. The Task Force will use…
Poster An interactive hypertext database of synoptic summaries of cardiovascular clinical trials
1998 Baltimore
Cucherat, Boissel, Haugh, Strang, Gueyffier
In cardiology there is a large number of clinical trials and this number increases each year. This makes it not feasible to remember and use all the information without help. A centralized system providing synthetic information for use in clinical pharmacology, evidence-based medicine and teaching…
Poster An quality assurance program evaluating prescription for tardive dyskinesia in French psychiatric hospitals: integration of Cochrane systematic reviews as an evidence-based reference
1998 Baltimore
Amsallem, Lachaux, Haugh, Boissel
Introduction: Neuroleptic-induced tardive dyskinesia is a disabling condition affecting about 20 to 30% of patients taking neuroleptics. In France, the importance of this condition is probably underestimated, and thus we decided to undertake a study of its prevalence, and psychiatrists'…
Poster Another decision to evaluate: choice of standardized mean difference effect size estimator
1998 Baltimore
Cannella
The standardized mean difference is the effect size generally recommended in clinical trials and other studies assessing treatment effects on outcomes measured on a continuous scale. Initially, the standard deviation of the control group, recommended for use in meta-analysis by Glass, was the…
Poster Antidepressants for the treatment of bulimia nervosa (BN)
1998 Baltimore
Bacaltchuk, Hay, Trefiglio, Mari, Hay
Introduction: BN is an eating disorder characterized by uncontrolled compulsive eating binges, followed by recurrent use of self-induced purging as vomiting, laxative abuse, or other inappropriate compensatory methods to prevent weight gain. The prevalence among adolescent and young adult females…
Poster Antidepressants versus psychtherapy for the treatment of bulimia nervosa (BN)
1998 Baltimore
Bacaltchuk, Hay, Trefiglio, Marti, Hay
Introduction: BN is an eating disorder characterized by uncontrolled compulsive eating binges, followed by recurrent use of inadequate compensatory behaviors in order to prevent weight gain. The prevalence among adolescent and young adult females is approximately 1%-3% (APA 1994). Antidepressants…
Poster Are you searching the right database? An example from mental health
1998 Baltimore
Taylor, McDonald, Adams
Introduction/Objective: To assess the coverage of the mental health literature within readily available bibliographic databases, and to consider the implications of this for the preparation of systematic reviews.
Methods: Using the Ulrich's Serials database, details of all journals and other…
Poster Assessing the quality of economic studies of health care-searching for an ideal instrument
1998 Baltimore
Gift, Kassler, Wang
Introduction/Objective: To develop a usable quantitative assessment tool which simplifies the analysis of economic studies, such as those estimating the cost effectiveness of prevention and cost of illness associated with sexually transmitted diseases (STDs).
Methods: A quantitative instrument was…
Poster Associated factors with abdominal aortic aneurysm: a systematic review of literature
1998 Baltimore
Cornuz, Pinto
Introduction/Objective: the mortality rate associated with rupture of abdominal aortic aneurysm (AAA) is very high. Optimal management for patients with AAA involves early identification and elective surgery. Data on risk factors for AAA might be useful for a selective screening among high-risk…