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Displaying 1 - 20 of 209 Index
Poster A GP evidence-based peer training program: the EPIDAS-Pneumo study
2000 Cape Town
Cornu, Cohen, Luciani, Boissel
Background: We present here the teaching methods used in an on-ongoing randomised trial aimed at evaluating the impact of a GP peer education program on vaccination for pneumonia prevention in elderly people. The primary endpoint is the number of patients hospitalised for pneumonia. Eighty French…
Poster A comparison of handsearching versus MEDLINE searching to identify reports of randomized controlled trials.
2000 Cape Town
Hopewell, Clarke, Lusher, Westby, Lefebvre
Background: To compare handsearching versus MEDLINE searching for the identification of reports of randomized controlled trials (RCTs) in specialized health care journals.
Methods: 22 specialised health care journals, published in the UK, were handsearched from 1970 to 1998, as part of a European…
Poster A cost benefit analysis using beta-blockers as adjunctive therapy in patients with congestive heart failure
2000 Cape Town
Raymund, Pasay, Charles, Loreta
Objective: To do a cost benefit analysis comparing standard therapy alone vs. standard therapy plus beta-blockers in the chronic treatment of congestive heart failure. Study Design: Economic evaluation using cost benefit analysis Materials &
Methods: A meta-analysis of double-blind, placebo…
Oral A meta-analysis of individual patient data with repeated outcome measures: treatment of type 1 diabetic microalbuminuric patients with ACE inhibitors.
2000 Cape Town
Hardy
Background: To assess the effect on albumin excretion rate (AER) of ACE inhibitors in normotensive type 1 diabetic patients with microalbuminuria and to assess whether the treatment effect varied across certain subgroups using individual patient data. To compare the results using different summary…
Oral A methodological review of the time series analysis designs in guideline.
2000 Cape Town
Matowe, Thomas, Ramsay, Grimshaw
Background: Time series analysis designs have frequently been used to evaluate quality assurance strategies; they attempt to assess whether an intervention has had an effect significantly greater than the underlying trend (1). They are more robust than simple (uncontrolled) before-and-after studies…
Poster A predictive modelling algorithms for meta-analysis Of individual patient data
2000 Cape Town
Trikalinos, Ioannidis
Abstract: We developed and evaluated methods for the analysis and interpretation of the baseline risk heterogeneity in meta-analysis of individual patient data (MIPD) based on information on predictive factors. We used data from a typical MIPD of 8 clinical trials (1792 patients, 2947 years of…
Poster A proposal for a register of methodological research
2000 Cape Town
Clarke, Olsen, Oxman, Hopewell
Abstract: This abstract is one step in a process of consultation on how to take forward the idea of a register of methodological research. Over the last few decades, the problems in identifying relevant trials of healthcare interventions have been described many times. Publication bias and…
Poster A randomized controlled trial of case-based small-group learning modules and/or individual prescribing portraits on prescribing behaviour
2000 Cape Town
Wright, Herbert, Wakefield, Maclure, Dormuth, Brett, Premi, Legare
Background: Financial Contribution from the Health Transition Fund, Health Canada Evaluations of educational interventions to improve physician performance are often poorly designed and measure questionable outcomes. Objectives: To conduct an educational trial using rigorous scientific principles,…
Poster A systematic approach to the evidence based laboratory medicine in Japan
2000 Cape Town
Nishibori, Kawai, Kanno, Kambe, Watanabe, Fukui, Ishida
Background: Practice of the evidence based medicine in the field of laboratory medicine requires a more appropriate approach than in other ordinary medical fields, because of the following reasons; 1. unlike the effectiveness of therapeutic measures which can be evaluated by comparing only two…
Oral A systematic review of case series of paediatric cardiac surgery
2000 Cape Town
Reeves, Vardulaki, Tsang, Bennett-Lloyd, O'Riordan
Background: There is often little or no evidence from randomised controlled trials (RCTs) on the effectiveness of health care interventions. When no RCTs exist, there is currently a debate whether non-randomised but comparative studies are better or worse than no evidence. For some surgical…
Poster A systematic review of short-term psychodynamic psychotherapies
2000 Cape Town
Abbass
Objectives: 1. To systematically review all controlled trials of Short-term Psychodynamic Psychotherapies (STPP). 2. To identify the scope of conditions treated with these modalities. 3. To assess for publication bias regarding STPP. 4. To test the hypotheses that a) STPP has become more…
Poster A systematic review of the scientific evidence on the effects of different follow-up policies for breast cancer patients
2000 Cape Town
Rojas, Russo, Fossati, Confalonieri, Liberati
Background: Despite the limited scientific evidence that they can really make a difference for patients quantity and quality of life, follow-up programs after primary treatment are commonplace in the care of breast cancer patients. Objective: To assess the effectiveness of different policies of…
Poster A systematic review of therapeutic equivalence: Inhaled versus oral steroids for adults with chronic asthma.
2000 Cape Town
Mash, Bheekie, Jones
Background: Guidelines for the management of chronic asthma have been published in several countries and all emphasise inhaled corticosteroids in the control of symptoms and the underlying inflammation of airways. In developing countries however the use of inhaled steroids at the primary care level…
Poster Abstract to full publication: findings from meetings on systematic reviews
2000 Cape Town
Hopewell, Clarke
Background: Approximately half of randomised trials of health care interventions that are initially presented in abstract form are subsequently published as full reports1. This has implications for systematic reviewers who strive to obtain a complete, unbiased set of relevant trials. It is…
Poster Access to the German and international Cochrane collaboration web site.
2000 Cape Town
Spinner, Koch, Antes
Background: The German Cochrane Centre (GCC) hosts and maintains its own web site for the German language speaking countries in Freiburg, Germany to provide information about the activities of the Cochrane Collaboration (CC) and about other important sources in the field of evidence-based medicine…
Oral Adding evidence from non-randomized patients to a randomized trial
2000 Cape Town
Schmoor, Olschewski, Schumacher
Abstract: Problems arising from treatment comparisons within non-randomized observational studies are well known, and the conduct of randomized clinical trials (RCTs) is the widely accepted gold standard in this area. In systematic reviews performed by the Cochrane Collaboration it is current…
Poster Aminopyridines for symptomatic treatment in multiple sclerosis
2000 Cape Town
Solari, Taus, Uitdehaag, Pucci, Giuliani
Background: Multiple sclerosis (MS) is the most important non-traumatic cause of neurological disability in young adults. Despite advance in curative treatment, symptomatic therapies also play an important role in the MS management. The potassium channel blockers 4-aminopyridine (AP) and 3,4-…
Poster An Initial analysis on the status quo of applying diagnosis test in imaging scientific study in China
2000 Cape Town
Rongbo, Yan, Zhihan, Fangfang, Jia, Xiangping
Objective: To analyze the status quo of applying diagnosis test in imaging scientific study in China, and to see whether reliable diagnosis can be provided to clinicians for accurate guidance of clinical management.
Method: We handsearched diagnosis test in 6 kinds of published imaging journals…
Poster An accessible method Of further regression analysis within Cochrane reviews: The problem Of demonstrating equivalence
2000 Cape Town
Brocklebank, Ram, Scally, Wright
Background: A review was performed under the Cochrane Airways group 'Pressurised metered dose inhalers versus all other hand-held inhaler devices to deliver corticosteroids for non-acute asthma ' (currently protocol on Cochrane Library). This shows no treatment effect between pressurised…
Poster An analysis Of the neurological Cochrane review group modules
2000 Cape Town
Annale, Cusi, Candelise
Background: One of the main aims of the Cochrane Neurological Network (CNN) is to help the neurological Cochrane Review Groups (CRG) in their work and avoid duplication. This analysis describes andcompares the activities of these CRG.
Methods: Ten Cochrane Review Groups mainly focus on the…