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Displaying 1 - 20 of 268 records Index
Poster A Cochrane Collaboration systematic review of melanoma incidence in randomized controlled trials of lipid-lowering agents
2004 Ottawa
Dellavalle, Drake, Graber, Hester, McNealy, Morelli, Schillin
Recent clinical trial, in-vitro, and animal study data suggest that lipid-lowering medications may be useful for the prevention and/or adjuvant therapy of melanoma. To further investigate this hypothesis, we have initiated a systematic review of melanoma outcomes in randomized controlled trials of…
Poster A Cochrane registry has multiple functions
2004 Ottawa
McGowan, Editorial Team
Background: The Effective Practice and Organisation of Care (EPOC) Review Group has a specialized Register which collects primary studies based on the following four designs, RCT (randomized controlled trial), CCT (controlled clinical trial), ITS (Interrupted time series) and CBA (controlled before…
Oral A challenging mixed literature review experience
2004 Ottawa
Pluye, Grad, Dunikowski, Stephenson
Background: Mixed methods are increasingly used in health research, and methods to integrate quantitative and qualitative data have been described[1,2]. However few publications examine the challenges of the mixed literature review. The Cochrane systematic literature review and the meta-study of…
Poster A combined database for meta-epidemiological research: characteristics of included trials
2004 Ottawa
Wood, Sterne, Jüni, Kjaergard, Moher, Royle, Schulz, Altman, Egger
Background: Bias in controlled trials research has been examined in a number of meta-epidemiological studies.(1-6), and findings from these studies have contributed to improving the quality of RCTs and meta-analyses. We have combined these studies to create a database that will be used to examine…
Poster A half day interactive workshop in systematic review and the Cochrane Collaboration: a University of Toronto site group initiative
2004 Ottawa
Wong
Objectives: To assess the effectiveness of a workshop module, designed to improve the knowledge on systematic reviews and the Cochrane Collaboration.
Methods: The educational intervention consisted of a single half-day workshop. The overall structure of the workshop was standardized to include 1.…
Poster A huge challenge: traditional Chinese medicine vs Cochrane systematic review
2004 Ottawa
Taixiang, Na, Guanjian, Juan
General: Traditional Chinese Medicine (TCM) is a 3000-year-old holistic system. It combined the use of medicinal herbs, acupuncture, food therapy, massage, and therapeutic exercise for both treatment and prevention of disease. TCM has its unique theories for concepts of etiology, systems of…
Oral A look inside the black box: a description of the editorial process at three leading biomedical journals
2004 Ottawa
Lee, Boyd, Bero
Background: There is a consistent body of literature documenting the problem of publication bias (the publication of study results based on the direction and statistical significance of study findings). However, most of this evidence is limited to self-report from authors and quantitative studies…
Poster A preliminary investigation on the psychological health status of SARS patients in the Chinese medical journals
2004 Ottawa
Zhang, Liu, He
Background: Though the outbreak of severe acute respiratory syndrome (SARS) has been passed, what has left for the patients after treatment? How much was paid attention to the SARS patients in their psychological health status besides the medicinal interventions? Objectives: To investigate the…
Oral A review of tools for assessing the quality of qualitative studies: implications for systematic reviews
2004 Ottawa
Harden
Background: The establishment of the Cochrane Qualitative Methods Group signals enthusiasm amongst reviewers for including qualitative studies in Cochrane reviews. These types of studies can complement trials by increasing our understanding of the experiences of those receiving and implementing…
Poster A survey on medical students perception, attitude toward evidence-based medicine in a medical school in Taiwan
2004 Ottawa
Yang, Liou, Lee
Background: Evidence-based medicine is an increasingly important concept in medical education and medical school curricula. EBM will help medical professionals effectively update themselves with medical knowledge. It seems to be necessary to incorporate EBM course into the medical education program…
Poster Addressing the information needs of the lay reader: how much is enough?
2004 Ottawa
Parker, Carrick
Background: The Cochrane Collaboration is dedicated to making current and accurate information about the effects of healthcare readily available via Systematic Reviews (SR) published on The Cochrane Library (CLIB). With a wealth of research information relating to breast cancer now on the CLIB,…
Poster Adverse events and adverse effects in systematic reviews: some methodological issues
2004 Ottawa
Vandermeer, Wiebe, Buscemi, Hartling, Klassen
Background: There are many issues one needs to consider when examining adverse effects or adverse events (AEs) in a meta-analysis. We plan to address these issues and present some sensitivity analyses on them using two systematic reviews conducted by our research group.
Objectives: 1) To summarize…
Oral Aluminium therapy in the prevention and treatment of silicosis: used for over 30 years in Canada but generally rejected elsewhere.
2004 Ottawa
Thomas
Background: It is hard to conceive the burden of occupational lung disease, particularly silicosis among miners that existed 60 years ago. Any possible preventative or treatment measures were eagerly considered by occupational health and chest physicians worldwide. In 1943 W D Robson, Medical…
Poster An investigation on the quality of randomized controlled trials in 11 non key medical journals of traditional Chinese medicine from 1995 to 2000
2004 Ottawa
Wei, Zhang
Objective: To identify the RCT of traditional Chinese medicine in the eleven non-key Chinese medical journals so as to submit the results to the CENTRAL and the Chinese Clinical Trial Database; if possible, to have a preliminary investigation of the quality of these trials ( RCT ) so as to provide…
Poster Applicability and clinical relevance of results in randomised controlled trials. The Cochrane review on exercise therapy for low back pain as an example
2004 Ottawa
Malmivaara, Koes, van Tulder, Bouter
Background: In systematic reviews of randomized controlled trials (RCTs) critical appraisal of methodological quality is considered important. So far little attention has been paid to the assessment of the applicability, and the clinical relevance of the results. Objectives: To formulate criteria…
Poster Application of GRADE in hematological malignancy: watchful waiting vs. immediate systemic treatment in indolent non-Hodgkins lymphoma
2004 Ottawa
Kho, Choong, Friedberg, Weeks, Schunemann
Background: Indolent, disseminated non-Hodgkin s lymphoma (NHL) is largely incurable with current therapies. Two fundamentally different approaches to initial management of asymptomatic patients have been advocated-- watchful waiting (WW) and immediate systemic treatment (IST). The National…
Poster Application of evidence-based medicine to drug policy making in China
2004 Ottawa
Sun, Wang, Li, Xiong, Zou, Sun, Tao, He
Background: Since Evidence-based medicine (EBM) was introduced into China, it has been largely applied to drug evaluation and clinician s selection of drug use. However, its application to drug administration and the attitudes of drug administrators toward EBM were not well defined.
Objective: To…
Poster Are trial size and reported methodological quality associated with treatment effects? Observational study of 523 randomised trials
2004 Ottawa
Als-Nielsen, Chen, Lotte Gluud, Siersma, Hilden, Gluud
Objectives: The objective of this study was to assess whether the size of a trial and five methodological quality components were associated with the estimated treatment effects in randomised trials.
Methods: Observational study of 523 randomised trials included in meta-analyses from Cochrane…
Poster Assessing methodological quality in a large research literature: the case of distance education comparison studies
2004 Ottawa
Bernard, Abrami, Wade
It goes without saying that the quality of a systematic review turns on the quality of the studies that are included in it. In strong literatures, where randomized trials are both possible and endemic to the research culture, it makes perfect sense to select only studies of the highest…
Poster Assessing methodological quality of primary studies and applying results in the cochrane reviews. An evaluation of the drugs and alcohol group s reviews.
2004 Ottawa
Minozzi, Davoli, Amato, Ferri, Vecchi, A. Perucci
Objective: To analyse:- 1. criteria used to evaluate the methodological quality of primary studies and how they have been classified in A,B,C,D as required by RevMan. 2. how the methodological quality of primary studies has been incorporated in the review both in the methods and in the results…