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Displaying 341 - 360 of 612 records Index

Oral Methods for configurational synthesis: extensions to traditional meta-analysis for addressing intervention complexity and contextual variation in reviews

2013 Québec City
O’Mara-Eves, Thomas
Background: One of the underlying principles of meta-analysis is that sufficiently similar trials are aggregated in order to gain greater precision of effect size estimate and confidence around that estimate. This assumption breaks down outside clinical settings where interventions tend to be…

Oral Methods for the assessment of the effectiveness of treatment sequences for clinical and economic decision making

2013 Québec City
Lewis, Wilkinson, Sutton, Woolacott, Hughes, Ruiz, Williams, Philips
Background: Treatment sequences relate to the order in which interventions are administered within treatment pathways. For many conditions several alternative treatments are available should patients respond poorly. The potential effectiveness of each may differ according to its position in the…

Poster Modifiable factors influencing recruitment in clinical trials

2013 Québec City
Oude Rengerink, Hooft, Bossuyt, Mol
Background: Patient recruitment in clinical trials often takes longer than expected. Trials with slow recruitment are more costly and an insufficient sample size leads to indecisive conclusions. At present, determinants of slow recruitment that could help recruitment of patients both before and…

Poster Moving from evidence to implementation for childhood vaccination communication strategies: synthesising programme experience from low income countries

2013 Québec City
Lewin, Hill, Ames, Bensaude de Castro Freire, Bosch-Capblanch, Cliff, Glenton, Kaufman, Lin, Muloliwa, Oku, Oyo-Ita, Rada
Background: Caregivers’ knowledge and perceptions regarding vaccination are key determinants of childhood vaccination status, and communication interventions are therefore important in providing information. A key challenge for policy makers in low income countries (LICs) is how best to integrate…

Workshop Navigating The Cochrane Library ***PARTICIPANTS: Please bring your laptops to this session

2013 Québec City
Stewart
Objectives: To provide users with a better understanding of the techniques available for navigating The Cochrane Library. Description: The workshop will provide basic and intermediate level users with an understanding of the most useful techniques for navigating The Cochrane Library…

Poster Navigating the rough waters of knowledge translation (KT) research: effective search strategies for systematic reviews with a KT focus

2013 Québec City
Chojecki, Boruff
Objectives: To discuss the role that literature searching/information specialists can play in the knowledge to action cycle and the challenges of searching within the research field of knowledge translation (KT); to present practical and effective literature searching techniques and methods used…

Poster Network meta-analysis in Health Technology Assessments: how frequently used and how necessary are they?

2013 Québec City
Ciapponi, García Martí, Glujovsky, Bardach, Alcaraz, Pichón-Riviere
Background: Network meta-analysis (NMA), in the context of a systematic review, is a meta-analysis in which multiple treatments (that is, three or more) are being compared using both direct comparisons of interventions within randomized controlled trials and indirect comparisons across trials based…

Poster Network meta-analysis of multiple outcome measures with extrapolation of effects across networks

2013 Québec City
Achana, Cooper, Bujkiewicz, Kendrick, Sutton
Background: Recent advances in meta-analysis have seen increased application of multivariate methods to evidence synthesis involving multiple outcome measures or multiple treatment effects. These methods are particularly appealing in evaluating the effectiveness of healthcare interventions because…

Poster New marketing and communication strategies of the Brazilian Cochrane Centre

2013 Québec City
Fioretti, Carvalho, Riera, Torloni, Martimbianco, Grande, Porfírio, Costa, Torres, Silva, Costa, Macedo, Silva, Puga, Melnik, Atallah
Background: In 2012, Brazilian Cochrane Centre (BCC) decided to increase dissemination of its activities to professionals and consumers, emphasizing the importance of looking for systematic reviews (SR) when facing health related decisions. Objectives: To report new communication and marketing…

Poster New teaching and research activities of the Brazilian Cochrane Center

2013 Québec City
Carvalho, Fioretti, Torloni, Riera, Martimbianco, Grande, Porfírio, Costa, Torres, Silva, Costa, Silva, Macedo, Melnik, Puga, Atallah
Background: The Brazilian Cochrane Centre (BCC) has increased its efforts to disseminate the culture of evidence-based health (EBH) to the general public. Objectives: To report new activities implemented by the BCC. Methods: Over the last months, volunteer collaborators of the BCC have held…

Poster No RCT is an island: how often do RCTs cite relevant existing Cochrane Reviews?

2013 Québec City
Middleton, Binnion, Shute
Background: Randomised controlled trials (RCTs) need to place themselves in the context of other studies, ideally through making reference to any existing systematic review in completed RCT publications. Objectives: To assess the extent of RCTs citing relevant Cochrane Reviews in existence…

Oral Non-randomised studies in systematic reviews of intervention effectiveness: a content analysis of Cochrane Systematic Reviews

2013 Québec City
Ijaz, Mischke, Ruotsalainen
Background: Non-randomized studies (NRS) are increasingly used as evidence for effectiveness of interventions in Cochrane Reviews. How and why NRS are included has not been evaluated to date. Objectives: to conduct an overview of practice of including NRS within the CC. Methods: We included…

Poster Obtaining confidential protocols to increase the completeness and accuracy of risk of bias assessments for RCTs: an example from recombinant human bone-morphogenetic protein-2 (rhBMP-2) for spinal fusion

2013 Québec City
Rodgers, Brown, Heirs, Higgins, Mannion, Simmonds, Stewart
Background: Risk of bias assessment is an integral part of a systematic review. The Cochrane risk of bias tool covers selection, performance, detection, attrition, and reporting biases. Trials are classed as ‘high’, ‘low’, or ‘unclear’ risk of bias. The ability to assess a trial confidently as ‘…

Poster On beyond endnote: doing more with search results

2013 Québec City
Witteman
Background: Your search results represent more than just days or weeks of hard work - they are also data, locked in a range of formats and difficult to analyze, re-purpose or transform. Objectives: This presentation demonstrates a collection of software tools that allow access to this data, as…

Poster Online access to personal health information as a key component of shared decision-making: a pilot study in severe mental illness

2013 Québec City
Menkes, Kidd, Southey, Orr, Christini-Crawford, Fitzgerald
Background: To pursue shared decision making, patients often request access to their medical records, yet doing so can be frustrating. E-health has the perceived advantages of cost efficiency, improved access and participation, and better service provision, but this is yet to be convincingly…

Poster Online capacity building in translating research into practice for Latin American researchers

2013 Québec City
Villanueva, Tzanova, Cuervo, Urrútia, Ueffing
Background: Researchers in Latin America and the Caribbean (LAC) encounter several constraints that hinder the better use of research for health improvement of the region’s population; research methodologies are not integrated in the medical school curricula and materials in Spanish are not…

Oral Opportunities for knowledge translation skill development through online learning

2013 Québec City
Dobbins, Ciliska, Yost, Forsyth, Chera, Mackintosh
Background: The National Collaborating Centre for Methods and Tools (NCCMT) aims to build capacity in knowledge translation for public health in Canada. In addition to in-person training, NCCMT offers online learning resources for skill development in English and French. These include online…

Poster Optimal use of GRADE in Cochrane Reviews to inform clinical practice guidelines

2013 Québec City
Neumann, Santesso, Akl, Vandvik, Alonso-Coello, Agoritsas, Elias, Mustafa, Schünemann, Guyatt
Background: The GRADE approach (short for Grading of Recommendations Assessment, Development and Evaluation) offers a transparent, explicit and systematic way to summarize evidence, rate its quality, and move from evidence to recommendations. Cochrane Reviews are a valuable resource to inform…

Poster Outcome domains reported by Chinese randomized controlled trials of postoperative analgesia for children

2013 Québec City
Sun, Zhang, Zhao, Tian, Yang
Background: Standardization of outcome domains and measures in pediatric pain randomized controlled trials (RCTs) would streamline designing and reviewing research protocols and articles, simplify and strengthen systematic reviews, and help clinicians make treatment decisions. The Pediatric…

Poster PEN - the global resource for nutrition knowledge translation

2013 Québec City
Armour, Byron, Kellie, Murray, Thirsk
Background: Dietitians translate research into practice when applying the science of nutrition to the feeding and education of individuals or groups in health and disease. Maintaining currency is challenging when knowledge is constantly expanding. In 2005 Dietitians of Canada launched a dynamic…