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Displaying 161 - 180 of 594 records Index
Oral Country-specific qualitative synthesis: harvesting pearls or grit?
2018 Edinburgh
Booth, Mshelia, Analo, Nyakango
Background: International qualitative evidence syntheses, as commissioned by the World Health Organization (WHO) and other agencies, offer valuable cross-country perspectives on issues such as facility-based delivery and respectful maternity care. Necessarily, multi-context syntheses seek to offer…
Oral Creating living systematic reviews with citizen scientists and machine learning
2018 Edinburgh
Elliott, Gordon, Noel-Storr, Thomas, Cohen, Hodder, Gilbert, Murano, Weiss, Synnot, Turner, Millard, Martin, Bridges, Casas, MacLehose, Chou, Wolfenden, Helfand
Background:
The barriers to patient and consumer participation in the production of systematic reviews are substantial. 'Citizen science' opens up new opportunities for co-creation of trustworthy, up to date evidence. In parallel, text mining and machine learning are now able to make…
Oral Creating open-access, evidence-based decision aids for patients with skin disease
2018 Edinburgh
Dellavalle, Cameron, Henderin, Reed, McLellan, O'Neil, Boyal, Tan
Background:
Millions of people globally suffer from common dermatology ailments such as acne and psoriasis and may benefit from shared decision-making tools to improve their health care.
Objectives:
To introduce online patient decision aids (PDAs) for skin disease, describe PDA content…
Oral Crowd-sourcing structured metadata to improve literature search efficiency
2018 Edinburgh
Kaiser, Sweeney, Brown
Background:
Scientific literature search tools are often designed to enable presentation of matches based on a relevance model of information retrieval. In the case of MEDLINE the medical subject headings and keywords system was implemented in the 1960s when there were around 100,000 articles in…
Oral Crowd-sourcing the identification of rehabilitation-relevant review: a Cochrane Rehabilitation initiative
2018 Edinburgh
Levack, Negrini, Rathore, Pollet
Background:
Cochrane Rehabilitation is a new Field within the Cochrane community which has a goal of disseminating rehabilitation-relevant evidence from the Cochrane Library to our global community. Currently, the Cochrane Library does not have a method for the identification of rehabilitation-…
Oral Cultural adaptation of knowledge translation tools for parents of children with acute illnesses
2018 Edinburgh
Hartling, Brandys, Zimmermann, Thomson, Scott
Background: Knowledge translation (KT) initiatives can inform consumer decision-making. Our team has developed evidence-based KT tools for parents; the tools use innovative modes of delivery and integrate art and parent narratives to optimize their appeal. We initially developed the tools in…
Oral Data Abstraction Assistant, a new tool, saves time without compromising the accuracy of data abstraction during systematic reviews
2018 Edinburgh
Saldanha, Smith, Jap, Canner, Schmid
Background:
Data abstraction during systematic reviews is typically error-prone and resource-intensive. We developed Data Abstraction Assistant (DAA) as a free and open-source tool that facilitates data verification and reproducible abstraction by allowing data abstractors to link abstracted…
Oral De-duplication: new methods to reduce the manual burden of systematic searches
2018 Edinburgh
Tuvey, Walsh
Background:
Systematic searches of multiple bibliographic databases and other sources are undertaken to conduct systematic reviews and develop health guidance. This approach results in numerous duplicate citations, which are time-consuming to identify and remove. The National Institute of Health…
Workshop Deciding when to include non-randomized studies of interventions in a Cochrane Review of an intervention
2018 Edinburgh
Reeves, Shea, Tugwell, Wells
Background:
Cochrane Reviews require a protocol prespecifying the methods. When non-randomized studies of interventions (NRSIs) are to be included, protocols need to specify additional details. Authors are encouraged to consider whether NRSIs should be included, and to justify the decision in the…
Poster Defining ranges for certainty ratings of diagnostic accuracy
2018 Edinburgh
Hultcrantz, Langendam, Leeflang, Lavergne, Ansari, Mustafa, Schünemann
Background:
The Grading of Recommendations Assessment, Development and Evaluation (GRADE) concept for certainty of evidence represents our confidence that the true effect lies above or below a threshold, or in a specified range. A clarification of how these concepts apply to certainty ratings of…
Poster Defining variation in outcome reporting: a review of systematic reviews in women’s and newborns' health
2018 Edinburgh
Rogozinska, van’t Hooft , Cooper
Background: Over the last five years, we have observed an increase in the registration of projects aiming to develop core outcome sets (COS) and address the inconsistencies in outcome reporting. The trend is particularly apparent in the area of women’s and newborns' health research. A recent…
Poster Definition of eligibility for non-randomised studies in 113 Cochrane Reviews of interventions to prevent healthcare-associated infections
2018 Edinburgh
López-Alcalde, Stallings, Cabir Nunes, Daheron, Fernández-Chávez, Bonfill Cosp, SEXCOMPLEX, Zamora
Background:
Randomized clinical trials (RCT) are difficult - or even unethical - in infection-control research. Thus, systematic reviews (SR) of interventions to prevent healthcare-associated infections (HAIs) can define non-randomized studies (NRS) as eligible. NRS cover different study designs…
Oral Delivering evidence in a patient-focused manner: the example of the European Breast Guidelines
2018 Edinburgh
Saz-Parkinson, Santesso, Plutecka, Les, Parmelli, Lerda`
Background:
The European Commission Initiative on Breast Cancer (ECIBC) aims to ensure and harmonise the quality of breast cancer services across European countries.
One of the pillars of this initiative is the development of evidence-based guidelines on breast cancer screening and diagnosis;…
Poster Delphi Method and Analytic Hierarchy Process to establish an indicator system to evaluate rational drug use in children with primary nephrotic syndrome
2018 Edinburgh
Lin
Background:
Nephrotic syndrome (NS) can be divided into three types: primary, secondary and congenital. Primary NS (PNS) accounts for about 90% of instances of NS in children, and is a common childhood glomerular disease. The treatment of children with PNS has been controversial and confused…
Oral Deriving percentage study weights in advanced meta-analysis models
2018 Edinburgh
Riley, Ensor, Burke, Jackson
Background: Percentage study weights break down the summary meta-analysis result into the relative contribution of each individual study, and are easily interpretable by patients and health professionals. They are especially important when some studies are potential outliers or at high risk of bias…
Poster Description of trials and systematic reviews exclusively retrieved by LILACS
2018 Edinburgh
Ciapponi, Glujovsky, Comande, Bardach
Background:
In a previous study, we found an overlap between LILACS and PubMed from 2006 to 2015. Out of all the articles identified, we found 1612 (0.3%) trials (RCTs) and 3578 (0.9%) systematic reviews (SRs) were retrieved exclusively by LILACS (Table 1).
Objectives:
To describe the…
Poster Descriptive analysis of non-randomized studies included in Cochrane Reviews regarding their availability in PubMed
2018 Edinburgh
Metzendorf, Richter, Bandeira-Echtler, Hausner, Waffenschmidt
Background:
Randomized controlled trials (RCT) are relatively easy to identify due to the availability of well-performing, validated search filters. This does not hold true for non-randomized study (NRS) designs. There are many uncertainties regarding the identification of NRS in bibliographic…
Poster Descriptive analysis of the first 1000 trials in Pan African Clinical Trial Registry (PACTR)
2018 Edinburgh
Ndwandwe, Pienaar, Mathebula , Reddy, Abrams, Lutje, Kredo
Background:
A clinical trials registry is a database in which key administrative and scientific information about planned, ongoing and completed trials is stored. The Pan African Clinical Trials Register (PACTR) aims to assist regional efforts towards transparency and harmonization of clinical…
Poster Design and validation of a search filter for LGBTQ+ populations
2018 Edinburgh
Parker, Wanner, Foster, Lackey
Background:
The health of lesbian, gay, bisexual, transgender and queer (LGBTQ+) people is a subject area that is challenging to search due to variant and changing terminology, which presents a challenge when developing comprehensive searches for systematic reviews on health topics specific to…
Poster Determining the degree of dissemination bias for health-related quality of life outcomes in antidepressant trials
2018 Edinburgh
Sharma, Rasmussen, Paludan-Müller , Gøtzsche
Background:
Dissemination bias distorts the true effectiveness of interventions, leading to unreliable results. Though health-related quality of life outcomes have been used in antidepressant trials, their results have rarely been published.
Objectives:
To determine the level of selective…