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Displaying 3141 - 3160 of 10301 records Index

Oral A forward search algorithm for detection of extreme study effects in network meta-analysis

2018 Edinburgh
Petropoulou, Salanti, Rücker, Schwarzer, Moustaki, Mavridis
Background: In a quantitative synthesis of studies via meta-analysis, it is likely that some studies provide a markedly different intervention effect or have a large impact on effect estimates and/or heterogeneity. There are several methods to identify outlying studies in a meta-analysis. Most of…

Oral A framework for meta-analysis of prediction model studies with binary and time-to-event outcomes

2018 Edinburgh
Debray, Damen, Riley, Snell, Reitsma, Hooft, Collins, Moons
Background: It is widely recommended that any developed prediction model - diagnostic or prognostic - is validated externally in terms of its predictive performance measured by calibration and discrimination. When multiple validations have been performed, a systematic review followed by a formal…

Poster A methodological research of non randomized controlled trials in network meta analysis

2018 Edinburgh
Ling, Ge, Yang
Background: The majority of network meta-analyses published to date have incorporated data from randomized controlled trials (RCTs) only, however, more and more network meta-analyses of treatment interventions include non-randomized trials (NRSs). NRSs can complement RCTs or address some of their…

Poster A model for network meta-analysis of rare events

2018 Edinburgh
Efthimiou, Rücker, Egger, Salanti
Background: The Mantel-Haenszel method has been used for decades now to synthesize data obtained from studies that compare two interventions with respect to a binary outcome. It has been shown to perform better than the inverse-variance method or Peto’s odds ratio when data are sparse. Network…

Poster A nationwide survey of the attitudes of doctors and dentists in training towards use of evidence-based practice

2018 Edinburgh
Hong, Jones, Cochrane UK and Ireland Trainees Advisory Group
Background: The use of best evidence is vital to improving patient outcomes yet the extent to which trainee clinicians are motivated to engage with evidence-based practice is unclear. Objectives: The Cochrane United Kingdom and Ireland Trainees Advisory Group (CUKI TAG) undertook a national…

Oral A new resource in the enhanced Cochrane Library: Cochrane Clinical Answers

2018 Edinburgh
Tort, Burch, Pettersen
Background: Cochrane Clinical Answers (CCAs) are an important tool for making the results from Cochrane Reviews accessible and usable at the point of care. They are evidence-based answers to the clinical questions addressed by Cochrane Reviews, covering a wide range of topics, and aimed primarily…

Poster A overview of systematic reviews about patients' values and preferences with AMSTAR II

2018 Edinburgh
Bai, Ling, Esoimeme, Yao, Wang, Shi, Dou, Chen, Tian, Wang, Yang
Background: These days more and more systematic reviews (SRs) are published to measure patients' values and preferences in different areas of diseases, but their methodological quality is varied and unclear. The AMSTAR II (A MeaSurement Tool to Assess systematic Reviews II) checklist…

Oral A patient and public involvement panel to explore complex evidence synthesis: a case study on hazardous and harmful alcohol drinking

2018 Edinburgh
Beyer, Angus, Brown, Caldwell, Craig, Edmondson-Jones, Harvey, Henn, Hickman, Lavoie, Michie, Neal, Rice, Kaner
Background: Patient and public involvement (PPI) is common in primary research, but less widespread in systematic reviews (SRs). We invited consumer partners to contribute to a SR and network meta-analysis investigating the effectiveness and cost-effectiveness of interventions for hazardous and…

Oral A patient perspective of using evidence for shared decision-making in a medical consultation

2018 Edinburgh
Brown
Background: I am a survivor of childhood leukaemia. I had a bone marrow transplant and have experienced multiple complications as result of chemotherapy and radiotherapy treatments. Recently I have had three episodes of spontaneous pneumothorax (collapsed lung) in 14 months. Healthcare…

Poster A pilot study on the efficacy of shared decision making in nutritional consultant clinics for patients with diabetes mellitus

2018 Edinburgh
Pan, Pan, Fan, Wang
Background: Diabetes mellitus (DM) is the fifth greatest cause of death in Taiwan, impacting 2.3 million Taiwanese. Current treatment guidelines recommend lifestyle modification and healthy eating. Nutritional counseling is an important component of diabetes care. Shared decision making (SDM) has…

Poster A practical toolkit for clinicians to locate best evidence to improve patient outcomes

2018 Edinburgh
Kendall, Ryu, Walsh
Background: Sinai Health System (SHS) is an internationally recognized academic health sciences centre affiliated with the University of Toronto. With more than 28,809 admissions a year, clinicians at SHS are often challenged with locating the best available published evidence at the time of need…

Oral A randomised trial of integrated machine-learning for systematic review 'Risk of bias' assessments

2018 Edinburgh
Arno, Wallace, McKenzie, Marshall, Thomas, Elliott
Background: Assessment of study risk of bias (RoB) is a key step in a systematic review but is very time-consuming. RobotReviewer is an open-access platform which partially automates RoB assessment using machine-learning (ML) and natural language processing. Covidence is a cloud-based systematic…

Poster A review of methods used for hazard identification and risk assessment of environmental hazards

2018 Edinburgh
Chartres, Norris
Background: Use of divergent methods to identify health risks posed by environmental hazards may hinder the goal of transparency and reduce the level of confidence the public may have in the recommendations made. There is no international standard for best practice in conducting hazard…

Poster A scale for measuring evidence-searching capability: a development and validation study

2018 Edinburgh
Chi, Tsai, Fang
Background: The ability to acquire the best evidence efficiently is important for busy healthcare professionals who have to make decisions within a limited time. However, the current available assessment tools in evidence-based medicine (EBM), e.g. Berlin questionnaire and Fresno test, were not…

Poster A scoping review of tools used to assess the quality of reporting of case report and case series studies

2018 Edinburgh
Wiyeh, Ochodo , Dube , Wiysonge
Background: Case reports and case series are important in the individualisation of clinical practice recommendations, for the reporting of adverse and beneficial effects of various treatments and in the description of new and unusual diseases. However, despite the availability of several tools…

Poster A search strategy for retrieving articles from the LILACS database in a systematic review of diagnostic accuracy studies: an experimental study

2018 Edinburgh
Pereira, Tersi, Puga, Atallah, Ribeiro, Macedo
Background: LILACS (Latin American Caribbean Health Sciences Literature) is described in the Cochrane Handbook for Systematic Reviews as one of the resources for systematic reviews of diagnostic test accuracy. Although many studies have already recognized the importance of LILACS in systematic…

Oral A statistical methodology to integrate the findings from studies of complex public health interventions

2018 Edinburgh
Shankar, Guddattu, Nair
Background: Public health interventions are often addressed as 'complex interventions'. Application of routine meta-analysis techniques to synthesise the results public health intervention studies provides a pooled estimate, which is diluted by the effect of complexity. Objective: To…

Poster A survey of patient-centered outcome for coronary heart disease

2018 Edinburgh
Kong, Yang, Liu, Wang, Liu
Background: Lack of patient-centered outcomes limits the usefulness of clinical trial evidence to inform healthcare decisions. Objectives: 1) To investigate outcomes about which patients with coronary heart disease (CHD) are most concerned. 2) To make recommendations for selecting outcome…

Poster A survey on the methodology of nursing clinical practice guidelines in the National Guideline Clearinghouse

2018 Edinburgh
Sun, Chen, Bu, Yu, Wang , Tian
Objectives: To analyze the current status of the methodology used in nursing clinical practice guidelines in the National Guideline Clearinghouse (NGC), in order to provide suggestions for researchers to develop and apply. Methods: We searched the NGC website for nursing clinical practice…

Oral A systematic and transparent process to support informed decisions for diagnostic tests in laboratory settings

2018 Edinburgh
Pecoraro
Background: Decision-makers sometimes neglect important criteria regarding the adoption of diagnostic tests that could benefit patients. A transparent and explicit approach based on evidence criteria is an efficient tool to guide decision-making processes. Objectives: We applied a…