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Poster Describing Heterogeneity in Meta-analysis Involving Cluster Randomized Trials: Normality versus Nonparametric Approaches of Random Effects Models
2002 Stavanger
Laopaiboon, B#246;hning
Objective: The purpose of this study was to compare the general linear mixed model (GLM) with the generalized linear mixed model (GLMM) for describing heterogeneity in meta-analysis involving cluster randomized trials in binary outcome.
Methods: The two approaches of GLM and GLMM were exemplified…
Poster Designing an Efficient and Precise Search Strategy for Observational Studies
2002 Stavanger
Wieland, Brodney, Dickersin
Objective: To describe the construction, sensitivity and precision of a maximally sensitive MEDLINE search for observational studies of a relationship between an exposure and disease. Productive search design strategies have been developed for identifying randomized controlled trials for…
Poster Development of an Optimal Search Strategy for Finding Trials Demonstrating ACE Inhibitor Blood Pressure Lowering Efficacy
2002 Stavanger
S Heran, M Wright
Objectives: Since its introduction in 1994, the search strategy recommended by the Cochrane Collaboration (Cochrane highly sensitive search strategy) has been adopted for use by many reviewers for the retrieval of controlled trials from Medline using Ovid and SilverPlatter. Our objective was to…
Poster Disseminating the Findings of Research: The NHS Centre for Reviews and Dissemination Experience
2002 Stavanger
A, CR, PM
Methods: This presentation will summarise the experience of CRD in their attempts to disseminate and promote the uptake of research findings within the NHS. It will describe CRD's unique distribution system based on the principles of relationship marketing that involves maintaining active…
Poster Do We Analyse Symptom Outcomes Correctly for Intervention Trials in Spontaneously Remitting Illnesses?
2002 Stavanger
Del Mar, Doust
Objectives: To model the effect of measurement of only one parameter for the outcome of spontaneous remitting illness.
Methods: Trials of intervention directed at symptoms for spontaneously remitting illnesses usually use time-to-recover (eg. time for a set percentage of people to recover; or…
Poster Does The Non-Randomised Controlled Study Have a Place in the Systematic Review? A Pilot Study.
2002 Stavanger
Ferriter, Huband
Objective: A major issue in systematic reviews is what types of studies should be included or excluded from the review. The Cochrane Collaboration has traditionally viewed the RCT as the 'gold standard'. However, many Cochrane reviews are inconclusive because of insufficient RCTs while…
Poster Does the Schedule of an Intervention Differ weather it is Used as Experimental or Control? The Experience of The Cochrane Drugs and Alcohol Group
2002 Stavanger
Marica, Laura, Marina, Simona, Carlo A
Objectives: To investigate the differences in dosage and modality of administration of treatments used as experimental intervention or as control.
Methods: We analysed the studies included in the 5 reviews on opioid detoxification already published on the Cochrane Library. From the tables of…
Poster Earlier Health Technology Assessment of Dying Patients' Therapy Baseline Reports
2002 Stavanger
Tie-jun, Pu, Xun, You-ping
Objective: Health services focus on improving, prolonging and saving lives. The earlier research indicated that end-stage care is inferior to prophylactics or timely care in terms of cost-effective, especially in the end of life. This earlier health technology assessment is to assess therapies for…
Poster Effect of Pacing Mode in Patients with Antibradycardia Pacing - a Meta-analysis after CTOPP Trial Does not End the Controversy
2002 Stavanger
Zagozdzon
Objective: Pacemaker therapy is widely recognized as effective treatment of symptomatic bradycardia. Older pacing technology enabled pacing of right ventricle only. Recent dual-chamber pacemakers can sense the activity of, and pace, both the atrium and the ventricle and thus are more physiologic…
Poster Effectiveness of Interventions for Opiate Withdrawal: An Overview of the Cochrane Systematic Reviews.
2002 Stavanger
Marica, Laura, Marina, Simona, Carlo A.
Objectives: To provide an overview of the reviews focused on treatments for opioid withdrawal.
Methods: Results are summarised across the reviews for homogeneous comparisons and outcomes.
Results: The total number of studies included in the original reviews is 37, with a total of 2498…
Poster Enhancing Dissemination of Mental Health Trial Evidence - The EU-PSI Project
2002 Stavanger
Pörtfors, Tuunainen, Wahlbeck, consortium
Background: Mental health and its different aspects are important in every society. Information about the effectiveness of treatments and interventions for different mental health conditions and problems is vital, not only for the efficient management of mental health care but also for satisfying…
Poster Finding a Haystack Among the Needles: Making Health Promotion and Public Health Reviews in The Cochrane Database of Systematic Reviews Available to Policy Makers
2002 Stavanger
Brunton, Kavanagh, Waters, Doyle, Shepherd, Rees, Harden, Oliver, Oakley
Objective: Using systematic reviews as one resource to inform health promotion and public health (HP&PH) policy can be challenging. HP&PH reviews are often difficult to locate within commercial and specialist registers. Searching difficulties will limit the acceptability and utility of…
Poster From Handsearch to The Cochrane Library: Encouraging the Conversion of Previously Published Meta-Analyses and Systematic Reviews to Cochrane Format.
2002 Stavanger
Roqué, Maria Garcia, Rigola
Objectives: 1. To develop and test an initiative to promote the conversion of previously published Spanish meta-analyses and reviews to Cochrane format. 2. To increase the production of new Cochrane reviews in Spain. Secondary objectives: 1. To identify reasons for authors not wanting to convert…
Poster Grades of Recommendation from Levels of Evidence: Are You Confused Yet?
2002 Stavanger
Falck-Ytter, Lelgemann, Booker, Antes
Background: When original research is cited, levels of evidence are increasingly applied, especially in clinical practice guidelines, health technology assessment reports or other reviews. The intention is to deliver the message, that not all research study designs are created equally. Levels of…
Poster Health Technology Assessment of Dialysis Membranes: Baseline Report
2002 Stavanger
Liu, Shi, Li, Zeng, Feng, Li
Background: Dialysis is a therapy designed to filter toxic substances from the blood of patients with kidney failure. A dialysis membrane is a core component of this treatment. Dialysis membranes can be made from cellulose, modified cellulose or synthetic materials, with great variance in the…
Poster Health Technology Assessment of Mifepristone and Misoprostol for Induced Abortion: Baseline Report
2002 Stavanger
Zou, Jiang, Li
Objectives: It is reported by WHO that about 150 thousand cases were requested for induced abortion every day, or 53 million for each year. Tietzec estimated that about one-third to half of women around the world would experience at least one induced abortion before menopausal period. At present,…
Poster High First Dose Quinine for Treating Severe Malaria
2002 Stavanger
Lesi, Meremikwu
Background: Malaria is an important cause of deaths worldwide. Quinine is either given as a series of uniform doses or with a high first (loading) dose followed by a series of uniform doses.
Objectives: To assess the clinical outcomes and adverse effects of a high first (loading) dose regimen of…
Poster How Important is the Size of a Reprint Order?
2002 Stavanger
Hopewell, Clarke
Objective: The number of reprints ordered for some journal articles can be very large. One measure of the importance of these articles is the number of times they are cited. This study aims to assess the impact of articles with very high reprint orders ('high-reprint articles') by…
Poster How a Cochrane Systematic Review Changed National and International Policy and Practice
2002 Stavanger
Francis, Goodall, Murray, Glasziou, Del Mar
Objective: To document the impact of a Cochrane Systematic Review on National and International Policy and Practice.
Methods: Broad search strategies were used to search electronic databases and the internet for relevant information. Hand searching of medical popular press publication was…
Poster How to Bring the Evidence to the Consumer?
2002 Stavanger
Sänger, Huth, Nickel, Weingart, Ollenschläger
Objectives: Health information for lay people in print or electronic format are internationally recognised as useful and important tool to help individuals making health decisions. The effectiveness of such consumer health information is dependent on their quality and accessibility. As large…