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Poster A comprehensive review of the evidence regarding the effectiveness of community-based primary healthcare in improving maternal, neonatal and child health: Summary and recommendations of the Expert Panel

2017 Cape Town [Global Evidence Summit]
Black, Taylor (deceased), Bhutta, Victora, Sacks, Perry
Background: The contributions that community-based primary healthcare (CBPHC) and engaging with communities as valued partners can make to the improvement of maternal, neonatal and child health (MNCH) is not widely appreciated. This unfortunate reality is one of the reasons why so few priority…

Workshop Issues in interpreting and presenting patient-reported outcomes in Cochrane reviews

2017 Cape Town [Global Evidence Summit]
Guyatt, Patrick
Learning objectives: 1) List the different alternatives for aggregating across different patient reported outcome (PRO) instruments measuring the same construct as presented in summary of findings tables in Cochrane reviews. 2) Choose an alternative for preparing the summary of findings table…

Oral Judging the quality of evidence in reviews of prevalence research: adapting the Hoy criteria

2017 Cape Town [Global Evidence Summit]
werfalli, Levitt, E. Engel
Background: Systematic reviews of prevalence aim to summarise data from individual studies so as to inform healthcare planning and resource allocation, and to assist policy makers and funding models. It is often challenging to judge the overall quality of research evidence in systematic reviews…

Special Session "Guidelines meet shared decision making. Happy ever after?"

2017 Cape Town [Global Evidence Summit]
Elwyn, Alper, Trevena, Agoritsas
Evidence-based medicine became relevant to all when guidelines were born and given special status, raising the stakes on how to summarise evidence from population-based research. But clearly, patients are not populations, they have quirks, opinions, stories to tell and preferences that cannot be…

Poster 'A complete shift in ownership': valuing contributions from consumers and other stakeholders in systematic reviews

2017 Cape Town [Global Evidence Summit]
Campbell, Pollock, Nunn, Synnot, Struthers, Goodare, Hill, Morris, Watts, Morley
Background: Active involvement of key stakeholders, including people with a lived experience of a healthcare condition, in conducting systematic reviews is now routinely recommended, to ensure that reviews are both accessible and clinically relevant. However, there is little guidance available…

Oral 'Real-real world evidence' to understand the use of health information systems for decision making

2017 Cape Town [Global Evidence Summit]
Zuske, Oliver, Bonfoh, Njepuome, Mandjate, Auer, Krause, Bosch-Capblanch
Background: Real-world evidence (RWE) can be defined as information obtained from heterogeneous sources outside clinical or academic research settings, and as a complement to data from experimental studies. We explored how RWE is produced, transformed, and, finally, used to inform decision making…

Poster A best-practice implementation project of the maintenance of totally implantable ports: Lessons from one high-volume centre

2017 Cape Town [Global Evidence Summit]
Shen, Xu, Zhang, Huang, Li, Hu, Chen, Ge
Background: The totally implantable port is a common central venous access device. however, the cost of implantation and maintenance is very expensive. At present, the main problem of the promotion and the use of implantable ports in China is lack of well-trained professional healthcare providers.…

Oral A catalogue of biases described in the literature, and their implications for ROBINS-I

2017 Cape Town [Global Evidence Summit]
Elbers, McAleenan, Sterne, Higgins
Background: Non-randomised studies provide evidence about adverse effects and long-term outcomes and are often included in systematic reviews about healthcare interventions. The ROBINS-I tool (Risk Of Bias In Non-randomised Studies of Interventions) facilitates an evaluation of risk of bias in…

Oral A checklist for the assessment of published indirect comparisons and network meta-analyses

2017 Cape Town [Global Evidence Summit]
Bender, Sturtz, Kiefer
Background: Systematic reviews provide an overview of the available studies on a certain topic. By means of meta-analyses pooled-effect estimates can be calculated if the considered data are sufficiently homogenous. Besides traditional meta-analyses, in which direct head-to-head studies comparing 2…

Poster A cluster randomised-controlled trial for alcohol-use disorders in HIV care clinics

2017 Cape Town [Global Evidence Summit]
Madhombiro
Background:Interventions for alcohol-use disorders (AUDs) in HIV-infected individuals have been primarily targeted for HIV risk reduction and improved antiretroviral treatment adherence. However, reduction in alcohol use is an important goal. Alcohol use affects other key factors that may influence…

Poster A comparison of different approaches for editing health-related information: An editor's satisfaction perspective

2017 Cape Town [Global Evidence Summit]
Rossetti, Rodríguez Vázquez, Ried, O'Brien
Background: The need to provide health information in Plain English (PE) for non-native speakers and for individuals with low literacy levels has been widely acknowledged (1, 2) . Use of PE has also been shown to facilitate translation. Numerous institutions (e.g. the Centers for Disease Control…

Poster A comprehensive review of the evidence regarding the effectiveness of community-based primary healthcare in improving maternal, neonatal and child health: Neonatal health findings

2017 Cape Town [Global Evidence Summit]
Sacks, Sakyi, Freeman, Perry
Background: Lack of access to safe delivery care, emergency obstetric care and postnatal care continue to be challenges for reducing neonatal mortality. This poster reviews the available evidence regarding the effectiveness of community-based primary health care (CBPHC) and necessary conditions for…

Poster A core outcome set for asthma management: Consensus work across NICE Guidelines, Cochrane Airways Group and the COMET Initiative

2017 Cape Town [Global Evidence Summit]
Tan, Cates, Dennett, Williamson, Taske
Background: The difficulties caused by heterogeneity in outcome measurement are well known to those involved in evidence synthesis including guideline developers. These issues could be addressed with the development and agreement on standardised sets of core outcomes. Currently, three pieces of…

Poster A creative way for knowledge translation: Using a short comedy play in local language to disseminate healthcare evidence to 'illiterate and semi-illiterate' villagers

2017 Cape Town [Global Evidence Summit]
CHEN, Wei, Si, Wang, Zhang
Background: There is growing attention to how evidence-based health knowledge can best be disseminated. A number of research and development projects have focused on the translation of best evidence aimed at clinicians, consumers and policy makers. While these projects failed to concern '…

Poster A database of systematic reviews in eyes and vision – a cross-section of the evidence available to underpin clinical practice guidelines and set the research agenda

2017 Cape Town [Global Evidence Summit]
Lindsley, Rouse, Hawkins, Rosman, Twose, Li, Scherer, Lum, Hooft, Scholten, Dickersin
Background: As the number of systematic reviews (SRs) published in the health literature grows, we need to alert users about reliability of the evidence presented. Mapping treatment recommendations to existing reliable SRs ensures clinical practice guidelines (CPGs) are evidence-based and highlight…

Oral A database to record the impact of fraud and misconduct in studies included in systematic reviews

2017 Cape Town [Global Evidence Summit]
Urquhart, MacLehose, Foxlee
Background: Primary studies, including clinical trials, can be retracted or corrected due to the identification of fraud, misconduct or mistakes caused by honest error. It is therefore important to have a process for identifying these post-publication changes in the source literature and then…

Special Session A dialog with funders: What approaches and activities ensure research achieves its expected impact?

2017 Cape Town [Global Evidence Summit]
Weiss, Green, Littler, Reeder, Kinn, Kern
[Old title: Global funding: Multi-agency approaches to knowledge translation/research uptake into action or bringing the research community into the policy decision-making process] Objectives: Share how funders work to support evidence uptake so that it has an impact.  Different approaches and…

Oral A fast-track method of adapting clinical practice guidelines at King Saud University Medical City (KSUMC), Riyadh, Saudi Arabia

2017 Cape Town [Global Evidence Summit]
Al-Ansary, Wahabi, Bawazeer, Abou Elkheir , Al-Swat, Amer
Background: In order to realise the national and international standards of accreditation, the clinical practice guidelines (CPGs) Program at KSUMC was launched as a quality improvement collaborative project with Bahamdan Research Chair for Evidence-Based Health Care and Knowledge Translation in…

Poster A flexible online tool for the management of complex evidence-synthesis projects

2017 Cape Town [Global Evidence Summit]
Pérez Rada, Zhang, Etxeandia-Ikobaltzeta, Wiercioch, Canepa, Nieuwlaat, Couban, Schünemann, Rada
Background:One of the possible solutions to address timeliness in the production of systematic reviews is parallelisation of tasks. However, in the context of large reviews, short times, or both, the capacity of parallelisation is limited. Even if more people can be recruited, it becomes difficult…

Oral A framework for meta-analysis of prediction models for binary and time-to-event outcomes

2017 Cape Town [Global Evidence Summit]
Debray, Damen, Reitsma, Collins, Hooft, Riley, Moons
Background: It is widely recommended that any developed - diagnostic or prognostic - prediction model should be externally validated across different settings and populations. When multiple validations have been performed, a systematic review followed by a formal meta analysis may help to…