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Displaying 6141 - 6160 of 10381 records Index

Oral The EMBASE project: an analysis of highlighted words and phrases

2014 Hyderabad
Noel-Storr, Dooley, Glanville
Background: The EMBASE project utilizes a crowd model to help screen search results for relevance within the Cochrane Central Register of Controlled Trials (CENTRAL). To help screeners, approximately 80 words or phrases were selected to be highlighted, some in yellow and some in red. The yellow…

Poster The Embase project: the first year

2014 Hyderabad
Dooley, Noel-Storr, Glanville
Background: A consortium of Metaxis, the Cochrane Dementia and Cognitive Improvement Group, and the York Health Economics Consortium responded to a call for proposals to take over management of the EMBASE project. The aim of the project was identify randomised and quasi-randomised trials from…

Workshop The Stats Café (today’s special: statistics for the terrified)

2014 Hyderabad
Trivella, Odutayo, Nolan, Drahota, Clarke
Objectives: To gain an understanding of common statistical concepts such as: risks, odds, P values, confidence intervals, and sample size. Description: This workshop involves working in small groups and rotating around the room to undertake a range of activities. On each table we will place…

Poster The X of UXG

2014 Hyderabad
Riis, Thomas, Mavergames
Background: The User Experience Group (UXG) was formed in early 2014 with the ambition to revolutionise technical development in Cochrane. It improves on the long-standing software advisory committees by consisting of a smaller number of Central Executive staff, able to focus more efficiently on…

Poster The benefits and harms of methylphenidate treatment for attention deficit hyperactivity disorder (ADHD) in children and adolescents: preliminary results

2014 Hyderabad
Storebø, Krogh, Ramstad, Danvad Nilausen, Rosendal, Skoog, Groth, Holmskov, Løgstrup Magnusson, Forsbøl, Buch Rasmussen, Kirubakaran, Zwi, Gillies, Gauci, Riegl, Maia, Simonsen, Gluud
Introduction: In this large Cochrane systematic review we will include about 150 randomised clinical trials (RCTs) and 220 non-randomised studies (NRS) for assessment of benefits and harms. The organizational and logistical challenges in conducting this review and synthesizing data were…

Poster The development of a quality assessment checklist for molecular marker studies

2014 Hyderabad
Stegeman, van Kempen, Willems, Hooft
Background: Systematic reviews are a cornerstone in biomedical research and evidence-based medicine. In order to acquire high level systematic reviews, adequate assessment of the methodological quality of included studies is important. In the last decades an increasing number of molecular…

Poster The effects of Pay-for-performance in health care systems with universal health coverage: a systematic review

2014 Hyderabad
Sermsuti-anuwat, Pavananunt, Rattanamongkolgul, Wibulpolprasert
Background: The results of Pay-for-performance (P4P) schemes in many countries vary substantially according to the various contextual factors and socio-economic conditions. Previous systematic reviews on P4P did not focus on different health system context. Currently, there is some uncertain…

Oral The future of review production for Cochrane

2014 Hyderabad
Mavergames, Thomas
Background: Cochrane's technology and processes for review production and evidence synthesis have served us well. RevMan, Archie and, more recently, the Cochrane Register of Studies (CRS) have provided a solid backbone to assist in moving Cochrane toward synthesizing and managing all…

Poster The impact of the Consolidated Standards of Reporting Trials (CONSORT) checklist on reporting of randomized clinical trials in traditional Chinese medicine

2014 Hyderabad
Peng, Zhang, Kang, Liu
Background: There is a paucity of data regarding whether the Consolidated Standards of Reporting Trials (CONSORT) statement has improved the quality of reports of randomized controlled trials (RCTs) on traditional Chinese medicine (TCM). Issues on the quality of reporting have not received as…

Oral The importance of process evaluation: a tale of two reviews

2014 Hyderabad
Kristjansson, Welch, Liberato, Francis
Background: We have completed two complex systematic reviews on food supplementation: one for young children and one for school children, which was recently updated. In addition to rigorous Cochrane methodology, we used process evaluation to understand which implementation factors were important…

Workshop The message: good communication of results (and caveats), and how to avoid Cochrane’s most common major errors

2014 Hyderabad
Trivella, Cumpston, Lasserson, Marshall, Ni Ogain
Objectives: To provide participants with practical guidance on using GRADE (Grading of Recommendations Assessment, Development and Evaluation) to ensure good practice, consistent communication of findings and the quality of evidence in Cochrane Reviews. Description: Through small group…

Oral The moral dimensions of meta-analysis: a grounded theory of the meta-analytic process

2014 Hyderabad
Macdonald, Carnevale, Chan, Steele, Shrier
Background: Discordant conclusions between meta-analyses occur even when meta-analysts are presented identical data, suggesting subjectivity is inherent in the “objective process”. Objective: To better understand the subjectivity in the meta-analytic interpretation process. Methods: We…

Poster The processing of Cochrane Open Access

2014 Hyderabad
Hives, MacLehose, Thomas
Background: ‘Open Access’ (OA) is a way of publishing scholarly research that makes it available, unrestricted, online. Cochrane OA means that authors choose to make their Cochrane Review or Protocol OA in the Cochrane Database of Systematic Reviews (CDSR) immediately upon publication (Gold),…

Oral The quality of evidence is a key determinant of strength of recommendations

2014 Hyderabad
Djulbegovic, Kaufman, Tobian, Kumar, Mhaskar, Guyatt
Background: According to the GRADE system, guidelines panels consider four factors when making recommendations: quality of evidence, balance between the intervention’s benefits and harms, resource use and patient’s values and preferences. However, no study to date has assessed the association of…

Poster The relationship between the external and internal validity of randomized controlled trials: a sample of hypertension trials from China

2014 Hyderabad
Zhang, Wu, Kang, Liu, Peng, Hong
Objectives: To explore the relationship between the external and internal validity of hypertension randomized controlled trials (RCTs) conducted in China. Methods: Comprehensive literature searches were performed in MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL…

Poster The risk of unblinding was infrequently and incompletely reported in 300 randomised clinical trial publications

2014 Hyderabad
Bello, Moustgaard, Hróbjartsson
Background: Blinding is an important methodological procedure to minimize bias in randomised clinical trials. Blinding procedures may not be effective, and loss of blinding, i.e. unblinding, occurs in an unknown proportion of trials. Objectives: To assess the proportion of randomised…

Poster The risk-of-bias profile of neonatal randomised-controlled trials in Cochrane reviews: are we better over the years?

2014 Hyderabad
Lai, Ong, Chaiyakunapruk
Background: The introduction of Neonatology as a subspecialty in 1960 has stimulated an enormous amount of neonatal research. A large proportion of neonatal randomised controlled trials (RCTs) are captured in the Cochrane Reviews. An integral part of a Cochrane Review is the risk-of-bias (RoB)…

Poster The snowball effect: promoting Cochrane evidence via social media

2014 Hyderabad
Littlewood, Riley
Background: Social media allows the exchange of information and ideas in virtual communities and networks and could be a useful tool to promote the use of Cochrane evidence. Objectives: To track a recently published Cochrane Oral Health Group Review, and see how it has been promoted via…

Poster The synthesis of economic evidence to improve global policy and equity in healthcare decision-making, using systematic reviews with hierarchical decision matrices

2014 Hyderabad
Jadotte, Holly, Salmond
Background: Patients, clinicians, policymakers and other stakeholders face numerous challenges in healthcare decision-making, including the greater complexity of healthcare systems and policies, the increasing global burden of chronic diseases, and the worldwide reality of dwindling healthcare…

Oral The use of systematic reviews in the design of randomized controlled trials of acupuncture: a systematic review

2014 Hyderabad
Kim, Lee, Choi, Lee, Lee
Background: One of the major purposes of systematic review is to guide future randomized studies to resolve current conflicts or address uncertainty in clinical practice. Concerns have been raised regarding waste in research due to inadequate use of existing evidence for planning or designing…