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Displaying 8621 - 8640 of 10241 records Index
Oral The accuracy of magnetic resonance imaging (MRI) versus computed tomography (CT) in the diagnosis of acute stroke: A Cochrane pilot review of diagnostic studies
2006 Dublin
Brazzelli, Sandercock, Wardlaw, Lewis, Deeks, Grazia Celani, Righetti
Background: The Cochrane Collaboration has decided to include systematic reviews of diagnostic test accuracy studies within its remit. We have completed a pilot review on the accuracy of magnetic resonance imaging (MRI) versus computed tomography (CT) for the diagnosis of acute stroke to test the…
Oral The association of allocation concealment and blinding with estimated treatment effect varies according to type of outcome: a combined analysis of meta-epidemiological studies
2006 Dublin
Wood, Egger, Lotte Gluud, Schulz, Altman, Jüni, Sterne
Background: A number of 'meta-epidemiological' studies have provided empirical evidence on sources of bias in randomized controlled trials. However, findings vary between these studies.
Objectives: To examine the associations of the adequacy of reported allocation concealment and…
Poster The development of the Iberoamerican Cochrane Network
2006 Dublin
Tort, Bonfill
Background: The currently registered 12 Cochrane Centres serve as reference centres for the different countries around the world. On the other hand, less than 10% of Cochrane reviews are authored by people based in developing countries and there is a need to extend the Collaboration to those…
Workshop The devil in the detail: data extraction forms for systematic reviews of complex interventions
2006 Dublin
Taylor, Hood
Objectives:
- To gain a better understanding of the challenges of extracting data from reports of trials, particularly from trials of complex interventions;
- To share strategies and good practice around the approach to data extraction and the design of data extraction forms for trials,…
Poster The effects of receiving public comments on systematic reviews
2006 Dublin
McDonagh, Peterson, Carson
Background: The Drug Effectiveness Review Project (DERP) is funded through multiple US State Medicaid offices. The systematic review process in DERP is committed to including the public in the process as much as possible. The impact of public input on systematic review processes is not yet known.…
Poster The impact of including grey and non-English literature on the combined effect estimates from nonrandomized add-on anti-epileptic studies
2006 Dublin
Maguire, Hutton, Marson
Background: Exclusion of non-English and grey literature (i.e. literature not published in peer-reviewed journals or having limited distribution) observational studies from systematic reviews may introduce bias and impact on overall treatment effect estimates.
Objectives: We have investigated the…
Poster The impact of including non-randomized studies in a systematic review: a case study
2006 Dublin
McDonagh, Peterson, Carson
Background: Systematic reviews utilize randomized controlled trials (RCTs) to evaluate competing interventions. It has been suggested that RCTs are limited by low generalizability due to strict inclusion criteria. While non-RCTs have broader generalizability, they also have limitations. The added…
Poster The inclusion of the estimated inter-study variation into forest plots for random-effects meta-analyses - a suggestion for a graphical representation
2006 Dublin
Skipka
Background: Meta-analyses are widely used to combine the results of clinical studies by calculating statistics for overall treatment effects. Basically, two different models exist for meta-analyses. The fixed-effect model (FEM) assumes each study is measuring the same treatment effect. Different…
Poster The lack of sex disaggregated data as a challenge to the review process: the case of a review of peer-based interventions for HIV positive women
2006 Dublin
Doull, Robinson, O'Connor, Tugwell, Wells
Background: In spite of the fact that women now make up almost half of those infected with HIV globally, there is very little research on interventions and/or programmes to support women once they are infected. This abstract discusses the issue of sex disaggregated data; a significant challenge…
Workshop The need to improve 'Implications for research' sections in Cochrane reviews
2006 Dublin
Chalmers
Objectives: To present the results of a survey of the content of 'Implications for research' sections in Cochrane reviews and the development of guidelines for improving research recommendations.
Summary: Decisions about funding new research studies are increasingly being informed by the…
Poster The plain language summary: Cochrane's most valuable product?
2006 Dublin
Santesso, Glenton, Oxman, Tugwell
Background: People who want to disseminate or use information from Cochrane reviews often do not have the time, energy or skills to filter through them for relevant information. However, systematic methods to present Cochrane reviews in plain language have been lacking.
Objectives: To develop a…
Poster The role of a Cochrane Review Group Trials Search Co-ordinator (TSC): review author experiences
2006 Dublin
McGuire
Background: The core function of Cochrane Review Groups (CRGs) is to facilitate the production and maintenance of high quality, relevant, up-to-date systematic reviews within their content area. To reach this objective each CRG is 'responsible for the development of a subject specific…
Poster The role of a Cochrane Review Group Trials Search Co-ordinator: working practices
2006 Dublin
McGuire
Background: The core function of Cochrane Review Groups (CRGs) is to facilitate the production and maintenance of high quality, relevant, up-to-date systematic reviews within their content area. To reach this objective each CRG is 'responsible for the development of a subject specific…
Poster The use of composite endpoints in clinical trials: a critical review
2006 Dublin
Ferreira-González, Permanyer Miralda, Busse, Bryant, Montori, Alonso-Coello, Guyatt
Background: Composite endpoints have become a popular strategy for assessing the impact of interventions in clinical trials, and it is important to clarify their merits and problems.
Objectives: To review systematically the literature pertaining to merits and demerits of composite endpoint use.…
Workshop To include, or not to include non-randomized controlled trials in systematic reviews: a novel approach to a controversial question
2006 Dublin
Shrier, Furlan, Oremus, Schachter, Brophy, Boivin, Rossignol, Kakuma, Platt, Steele
Objectives: To provide a forum for interactive discussion on emerging evidence that may affect the validity of systematic reviews with restricted inclusion criteria.
At the conclusion of the workshop, participants will:
- understand theoretical arguments for and against different inclusion…
Workshop Train the trainer
2006 Dublin
Scherer, O'Connor, Young, Mathew, Siegfried
Objectives: At the conclusion of the workshop, participants will be able to:
- identify and access appropriate materials useful in teaching others how to start and complete a systematic review;
- decide on inclusion of programme topics and models for in-person training;
- provide examples of how…
Poster Translating Cochrane evidence into practice in the Ministry of Health, Sri Lanka
2006 Dublin
Vidanapathirana, Randeniya
Background: Sri Lanka is a country which maintains a satisfactory level of health indicators compared to the South Asian region. The Ministry of Health provides more than 80% of the health service to the Sri Lankan population. Evidence-based medicine is included in the medical curriculum and very…
Poster Transparency enhancement for reports of randomized controlled trials in behavioral medicine
2006 Dublin
Falzon, Trudeau, Davidson
Background: As presented at last year's Colloquium, the now registered Cochrane Behavioral Medicine Field advocates for the inclusion of study details (participants, provider, setting) of interventions. These details are important in addressing the generalizability of a particular randomized…
Poster Trial sequential analyses of 145 Cochrane Neonatal Group meta-analyses considering adequacy of allocation concealment and heterogeneity
2006 Dublin
Brok, Wetterslev, Thorlund, Gluud
Background: Meta-analyses may commit Type 1 errors due to inclusion of biased trials and multiple testing when updating. To account for such errors, meta-analyses may be analysed with trial sequential boundaries (TSB) to determine when convincing evidence is reached1,2. TSB require calculation of…
Workshop Trials Search Co-ordinators' discussion forum (advanced)
2006 Dublin
Lefebvre
Objectives: To provide a forum for experienced Trials Search Co-ordinators who have been in post for more than four years to meet together and discuss with each other, facilitated by an experienced information specialist, issues chosen by them which are important to them in their work.
Summary:…