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Displaying 21 - 40 of 954 Index
Poster A framework to promote evidence use
2017 Cape Town [Global Evidence Summit]
Moratti
Background: The expectations of what evidence produces and why has shifted over the last years. The use of evidence increasingly matters to clients in the international-development sector seeking value of money for their investment and expecting more explicit 'impact' and 'uptake…
Oral A large-scale comparison between the global conduct of randomised-controlled trials and the global burden of diseases
2017 Cape Town [Global Evidence Summit]
Atal, Trinquart, Ravaud, Porcher
Background: Concerns exist about whether the allocation of resources in health research is aligned with public health needs, in particular in low-resource settings.
Objectives: We aimed to evaluate the alignment between the effort of health research through the conduct of randomised-controlled…
Poster A linked evidence synthesis evaluating mental health interventions for children with long-term conditions: Communicating implications for policy and practice
2017 Cape Town [Global Evidence Summit]
Moore, Shaw, Nunns, Rogers, Garside, Ukoumunne, Shafran, Heyman, Ford, Dickens, Walker, Titman, Anderson, Viner, Bennett, Logan, Thompson-Coon
Background: We have recently completed a project which involved two linked systematic reviews and an overarching synthesis evaluating the effectiveness and experiences of mental health interventions for children and young people (CYP) with long-term physical conditions.
Objectives: To work with…
Oral A linked-evidence synthesis evaluating interventions aiming to improve the mental health of children with long-term conditions: Reflections on stakeholder consultation
2017 Cape Town [Global Evidence Summit]
Nunns, Shaw, Moore, Rogers, Garside, Ukoumunne, Shafran, Heyman, Ford, Dickens, Walker, Titman, Anderson, Viner, Bennett, Logan, Thompson Coon
Background: We have recently completed a project which involved two linked systematic reviews and an overarching synthesis evaluating the effectiveness and experiences of mental-health interventions for children and young people (CYP) with long-term physical conditions (LTC). We engaged in…
Oral A map of maps: evidence for the sustainable development goals
2017 Cape Town [Global Evidence Summit]
Phillips, Coffey, Tsoli, Stevenson, Snilstveit, Masset, Eyers
Background: The last decade has seen an increase in production of impact evaluations and systematic reviews aimed at identifying effective development interventions. This growth presents a challenge – how to ensure existing evidence is accessible to decision makers, that new studies avoid…
Oral A mixed-methods evaluation to improve the adaptability of WHO evidence-informed guidelines for nutrition actions
2017 Cape Town [Global Evidence Summit]
Dedios, Esperato, De-Regil, Peña Rosas, Norris
Background: It is expected that global guidelines are informed by rigorous evidence and procedures. Yet the process of guideline development itself rarely undergoes the same scrutiny. In particular, there is limited information on whether countries find guidelines easy to adopt and adapt. This…
Poster A new evidence-based cancer care model for the Brazilian health system
2017 Cape Town [Global Evidence Summit]
Pazos, Scaff, Sznejder, Teich, Baldotto, Braga, Goldberg
Background: Cancer is a growing public health concern in Brazil with 596 000 new cases projected for 2016. The most prevalent are breast, prostate, cervix, lung and colorectal cancer, excluding non-melanoma skin cancer. The rates of late diagnosis and mortality are high. Figs.1 and 2.…
Workshop A new instrument to assess Risk of Bias in Non-randomised Studies of Exposures (ROBINS-E): Application to studies of environmental exposure
2017 Cape Town [Global Evidence Summit]
Morgan, Sterne, Higgins, Thayer, Schunemann, Rooney, Taylor
Objectives: To introduce a new tool for assessing risk of bias in non-randomised studies of exposures, and illustrate its application to studies of environmental and occupational exposure.
Description: Systematic reviews should include rigorous risk-of-bias assessments of included studies. We…
Oral A new instrument to assess the credibility of effect modifiers
2017 Cape Town [Global Evidence Summit]
Schandelmaier, Sun, Briel, Ewald, Bhatnagar, Devji, Foroutan, Brignardello, Sadeghirad, Guyatt
Background: Debates regarding the credibility of effect modifiers are often contentious. Although it is desirable to identify effect modifiers that explain heterogeneity of treatment effects, subgroup analyses may lead to spurious inferences of subgroup effects in randomised trials and meta-…
Oral A new tool to measure credibility of studies determining minimally important difference estimates
2017 Cape Town [Global Evidence Summit]
Devji, Carrasco-Labra, Lytvyn, Johnston, Ebrahim, Furukawa, Patrick, Schünemann, Nesrallah, Guyatt
Background: The ability to interpret results of patient-reported outcome measures (PROMs) and to judge the magnitude of effect (for instance, as large, moderate, small but still important, or negligible) is critical for their use in healthcare decision making. The most common reference point for…
Poster A novel method for benefit-harm assessment based on individual patient data determines benefit-harm balance over time
2017 Cape Town [Global Evidence Summit]
Aschmann, Boyd, Mularski, Sheehan, Bennett, Wilson, Yu, Leff, Puhan
Background: Systematic reviews alone are often not sufficient to inform treatment decisions and guideline development as the evidence needs to be contextualised and patient values and preferences need to be considered. Quantitative benefit-harm assessments (BHA) have become more common to address…
Oral A novel method for modelling interactions between the components of complex interventions in networks of randomised trials
2017 Cape Town [Global Evidence Summit]
Chaimani, Porcher, Ravaud, Mavridis
Background: Complex interventions consist of multiple interacting components whose effect on the outcome is not easily discernible. Therefore, such interventions may be better investigated within a network of trials that allows sharing information across studies. Several models have been suggested…
Special Session A panoramic view of rapid reviews: Uses and perspectives from global collaborations and networks
2017 Cape Town [Global Evidence Summit]
Garritty, King, Stevens, Soares-Weiser, Phillips, Norris, LAURENCE, Nussbaumer-Streit, Gartlehner, Akl
Purpose:
To exchange ideas about how rapid reviews have evolved as a useful information tool to support evidence-informed policy and practice.
Objectives:
Participants will have the opportunity for information sharing with rapid review producers, decision-makers and providers, and…
Oral A practical guide to expand integrated paediatric primary care: the PACK Child development process
2017 Cape Town [Global Evidence Summit]
Picken, Hannington, Fairall, Cornick
Background: With revolutionary strategies like the World Health Organization’s Integrated Management of Childhood Illness (IMCI) and the advent of interventions like the rotavirus and pneumococcal vaccines, the burden of childhood disease is shifting with mortality from infectious causes declining…
Workshop A practical workshop on how to use QUADAS-2 in a systematic review
2017 Cape Town [Global Evidence Summit]
Whiting, Reitsma, Leeflang
Objectives: To introduce QUADAS-2 and provide practical guidance on how to use the tool to assess the quality of diagnostic test accuracy (DTA) studies.
Description: The workshop will be split into two sessions:
Introduction to QUADAS-2:
The first session will be a brief overview of the…
Poster A principled and pragmatic critique of the use of confidence intervals and post hoc power analyses in systematic reviews
2017 Cape Town [Global Evidence Summit]
TUFANARU
Background: Confidence intervals (CIs) computed in frequentist statistics for the quantitative results of systematic reviews of the effects of interventions are recommended in the evidence-based practice literature (EBPL) in general and in the widely used approach known as the Grading of…
Oral A proposed framework for developing quality-assessment tools
2017 Cape Town [Global Evidence Summit]
Whiting, Wolff, Mallett, Simera, Savović
Background: Quality assessment of included studies is a crucial step when preparing systematic reviews. Although it is possible for reviewers to simply assess what they consider to be key components of risk of bias (ROB), this may result in important sources of bias being omitted, inappropriate…
Poster A qualitative systematic review of the experiences and support needs of newly graduated nurses during community service in South Africa
2017 Cape Town [Global Evidence Summit]
Ologun, Chipps, Daniels, Pimmer
Background: South Africa’s Community service nurses (CSN) programme requires nurses to serve in rural and undeserved areas. The programme is very relevant from developmental perspectives because it marks the first work experience for many nurses after graduation. It is also one of the key pillars…
Poster A quality assessment of Health Management Information System (HMIS) data for maternal and child health (MCH) in Jimma Zone, Ethiopia
2017 Cape Town [Global Evidence Summit]
Ouedraogo, Kurji , Abebe, Labonté, Morankar, Bedru, Bulcha, Abera, Roy-Gagnon, Kulkarni
Background: HMIS data in developing regions have often been identified as incomplete and inaccurate, which can jeopardise their usefulness in guiding and reaching national health targets. High-quality information is even more important for populations in which the burden of disease and mortality is…
Poster A review of contemporary clinical study protocols approved by research ethics committees in Denmark to assess if earlier trials were cited
2017 Cape Town [Global Evidence Summit]
Paludan-Müller, Vive, Jørgensen, Gøtszche
Background: A new trial should always be justified by reference to earlier, similar trials, if possible, ideally in the form of a systematic review of such trials. Unfortunately, this is not always the case which may lead to superfluous trials exposing participants to known inferior treatment.…