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Oral 'Spring-cleaning' of Cochrane reviews and clinical guidelines in order to co-ordinate Cochrane reviews and clinical practice
2005 Melbourne
Brok, Greisen, Christian, Gluud
Background The results of systematic reviews should be considered in clinical guidelines.
Objectives: To examine the agreement between systematic reviews completed by the Cochrane Neonatal Review Group and clinical guidelines for new-borns at a university department in Denmark.
Methods: Two…
Oral A Community of Practice implementing evidence
2005 Melbourne
Huckson, Yeoh, Ferma
Introduction: The National Institute of Clinical Studies (NICS) is Australia's leading agency to close important gaps between best available evidence and current clinical practice. NICS tests and develops ways to support clinicians in the implementation of evidence.
Communities of Practice…
Oral A better gold pan: capturing RCTs with more precision
2005 Melbourne
Anthony, Hill, Johnson, Stokes
Background: The quest to find gold nuggets with a gold pan is a time-consuming but rewarding task. Imagine the value of a pan that found all gold nuggets without having to sift through as much dirt. The current pan used to find gold nuggets for a systematic review is the Highly Sensitive Search…
Poster A bivariate meta-analysis of sensitivity and specificity: accuracy of maternal serum human choriongonadotrophin (MShCG) determination in the prediction of pre-eclampsia
2005 Melbourne
Cnossen, van der Post, Mol, Khan, ter Riet
Background: Pre-eclampsia, a syndrome of hypertension and proteinuria, is a leading cause of maternal and perinatal mortality and morbidity. Early prediction of pre-eclampsia may be used to target effective early treatment at high-risk women.
Objective: To systematically review the accuracy of…
Oral A modified test for small study effects in meta-analyses of controlled trials with binary endpoints
2005 Melbourne
Harbord, Egger, Sterne
Background: Publication and related bias in meta-analysis is often examined by checking for asymmetry in funnel plots of the treatment effect against its standard error. Formal statistical tests of funnel plot asymmetry have been previously proposed (Begg & Mazumdar, Biometrics 1994, Egger et…
Oral A priority-setting mechanism for national evidence-based consumer health information: the criteria and their application to Cochrane reviews
2005 Melbourne
Bastian, Burger, Zschorlich
Background: The Institute for Quality and Efficiency in Health Care (IQWiG) was established in 2004 by the German federal parliament. It is an independent scientific organisation with several legislative responsibilities designed to improve the evidence basis of the health care services. One of…
Poster A shortcut for developing evidence based pregnancy guidelines by adapting already existing ones to local constraints in Belgium
2005 Melbourne
Zhang, Alexander, Spitz, Lodewyckx, Peeters, Temmerman, Mambourg, Ramaekers
Background: Since the 1990s, practice guidelines have became commonplace in all fields of medicine and surgery. Most evidence based (EB) guidelines have been developed in the larger high income countries, such as the US, UK, France, Canada and Australia. One explanation for this phenomenon is the…
Poster A simplified search strategy for identifying randomised controlled trials for systematic reviews of health care interventions: a comparison with more exhaustive strategies
2005 Melbourne
Royle, Waugh
Background: It is generally believed that exhaustive searches of bibliographic databases are needed for systematic reviews of health care interventions. The CENTRAL database of randomized controlled trials (RCTs) has been built up by exhaustive searching. The CONSORT statement aims to encourage…
Workshop A systematic approach to involving consumers in the review process
2005 Melbourne
Herxheimer, Gyte
Objective: To discuss ways in which CRGs can systematically engage the help of consumers at all stages of producing a review, and to design a pilot project for the purpose.
Description: Up to now, in general, consumers seem to have been relatively little involved in the processes of producing…
Poster A systematic review of physical tests used in the diagnosis of shoulder impingement: a Cochrane experience
2005 Melbourne
Hanchard, Handoll
Background: Impingement is one of the most common causes of shoulder pain in adults, and results from the pinching of various soft-tissue structures adjacent to or within the shoulder joint on movement. The structures involved may include the rotator cuff (a musculo-tendinous complex surrounding…
Poster A tale of four review groups
2005 Melbourne
Pennick, Gillespie, Maxwell, Mayhew
Background: The core function of Collaborative Review Groups (CRG) is to facilitate the production and maintenance of high quality, relevant, up-to-date systematic reviews within their content area. To accomplish this, a CRG recruits, trains and gives ongoing support to their contributors - authors…
Poster Accuracy of the Spanish translated conclusions of Cochrane systematic reviews
2005 Melbourne
Ciapponi, Burls, Irazola
Background: A part of Cochrane Collaboration's mission is to make and disseminate systematic reviews (SR) of healthcare interventions. Since 1998, the Iberoamerican Cochrane Centre translates Cochrane SR into Spanish, which now are available to a great population of Spanish-speaking people…
Poster Actual usage of the Cochrane Library in teaching hospitals in Australia
2005 Melbourne
Singhal, Singhal
Background: The Cochrane Library is presumably one of the best and most popular databases for evidence based medicine. The question we had in our minds before undertaking this study was to know the actual usage of database if availability is not an issue.
Objectives: To investigate the perceptions…
Workshop Addressing dilemmas and conflicting interests faced by Cochrane review authors
2005 Melbourne
Clarke, Gabriel Cuervo
Building on the stimulating debate within this workshop in Ottawa, we will encourage participants contributing to the preparation and maintenance of evidence-based summaries and reviews to consider situations in which they would face ethical dilemmas, and discuss ways of addressing these situations…
Poster Adjustment for covariates in non-randomized studies: propensity score based methods vs classical regression models
2005 Melbourne
Schmoor, Caputo, Graf
Background: Randomized controlled trials (RCTs) are regarded as the gold standard for the comparison of treatments in clinical trials. Systematic reviews performed by the Cochrane Collaboration focus mainly on results of RCTs. Nevertheless, evidence from non-randomized studies and their inclusion…
Poster African Trials Register: 5 years later, where are we now?
2005 Melbourne
Pienaar
Background: On the African continent the majority of countries are developing countries. Given the more extreme limitations in health resources in these countries, there is a greater need for prioritization of healthcare expenditure. Consequently there is a greater need for the best available…
Poster Agreeing to disagree: an analysis of the responses to critical appraisal questions in postgraduate students
2005 Melbourne
Petherick, Cullum, Bland
Background: Previous studies have shown considerable variability of the reliability of different raters to achieve consistant results when undertaken quality assessments.
Objectives: To determine the agreement between post-graduate health sciences students using commonly used critical appraisal…
Oral An empirical comparison of methods for meta-analysis of studies of diagnostic accuracy
2005 Melbourne
Harbord, Bachmann, Shang, Whiting, Deeks, Egger, Sterne
Background: Reviews of diagnostic test accuracy studies are being incoporated into the Cochrane Collaboration. There is limited practical experience with statistical methods for such reviews, and uncertainty as to the most appropriate choice of method.
Objective: To compare the results of four…
Poster An examination of the impact of different types of trial materials included in the Cochrane reviews of interventions for treating distal radial fracture in adults
2005 Melbourne
Handoll
Background: The five Cochrane reviews of the evidence from randomised and quasi-randomised controlled trials cover all the key interventions on this topic. No trial is excluded on the basis of its trial report(s). All materials identified for each included trial are evaluated and referenced.…
Poster An holistic research design for Integrative Medicine
2005 Melbourne
Simpson
Background: While directing his private health centers from the early seventies, the author commenced evolving his formula for Integrative Medicine (IM). In teaching his self help principles for health promotion, he was obliged to show the effectiveness of his centers and consequent follow up…