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Displaying 161 - 180 of 350 records Index

Workshop Individual participant data (IPD) meta-analysis of risk prediction studies

2014 Hyderabad
Debray, Moons, Reitsma, Riley, Altman
Objectives: Participants will be introduced to individual participant data (IPD) meta-analysis in risk prediction research. We will discuss the opportunities and challenges of combining IPD from multiple studies when developing and/or validating a risk prediction model. Appropriate statistical…

Poster Informing the methods for public health overview reviews: a descriptive analysis of Cochrane and non-Cochrane public health overviews

2014 Hyderabad
James, Baker, Costello, Francis
Background: Overviews of systematic reviews (SRs) are useful for public health policy; however there is an absence of Cochrane Overviews covering public health (PH) topics. Objectives: We sought to analyze the methodological approaches used in existing Cochrane Overviews and Protocols for…

Poster Instant overviews, and beyond: the case for standardizing reporting in the characteristics of included studies tables

2014 Hyderabad
Struthers
Background: There will be many cases where several single intervention reviews are written for the same patient population. Currently patients, carers and the professionals advising them often have to use several Cochrane Reviews to help them make a decision about a range of treatment options…

Workshop Integrating quantitative and qualitative research evidence: mixed-method synthesis approaches for complex reviews

2014 Hyderabad
Hannes, Thomas, Noyes, Garside, Harden
Objectives: Mixed-method reviews require the combined use of qualitative and quantitative research evidence. They have recently gained popularity in the context of evaluating complex interventions. While there is a wealth of literature discussing the integration of primary quantitative and…

Workshop Interpreting results of Cochrane Reviews and 'Summary of findings' tables

2014 Hyderabad
Santesso, Mustafa, Rojas, Meerpohl, Schuenemann, Akl, Brozek, Brignardello-Petersen
Objectives: To learn to use GRADE (Grading of Recommendations Assessment, Development and Evaluation) to interpret findings and to create a 'Summary of findings' (SoF) table. Description: The GRADE criteria have been adopted by the Cochrane Collaboration to evaluate the quality of…

Oral Interpreting trial results following use of different intention-to-treat approaches for preventing attrition bias: a meta-epidemiological study

2014 Hyderabad
Døssing, Tarp, Furst, Gluud, Beyene, Brandt Hansen, Bliddal, Christensen
Background: In randomized clinical trials (RCTs) exclusion of participants post-randomization from the final analysis population frequently happens. This leads to deviations from the intention-to-treat (ITT) principle, potentially leading to attrition bias. Modified ITT (mITT) is commonly used as…

Oral Intervention Component Analysis (ICA): enhancing the “implementability” of review findings on complex interventions

2014 Hyderabad
Sutcliffe, Thomas
Background: Decision-makers often find it difficult to draw clear messages for implementation from systematic reviews due to inadequate detail in their descriptions of complex interventions. Detailed scrutiny of intervention components allows reviewers to consider whether certain features are…

Poster Interventions for the control of childhood obesity in the South Asian region: a systematic review

2014 Hyderabad
Noronha, Dsouza, Nair, Nayak, Mithra, Unnikrishnan, Mujja
Background: The global epidemic of obesity in many countries throughout the world has posed a great public health challenge in the early 21st century. There was no systematic review that specifically looked at effective intervention strategies to control childhood obesity in South Asia or low-…

Oral Introducing LATITUDES: a library of assessment tools and instruments used to assess data validity in evidence syntheses

2014 Hyderabad
Whiting, Wolff, Savovic, Simera, Mallett
Background: Evidence syntheses provide the most reliable form of evidence for decision makers. A formal assessment of the validity of included studies is an essential component of any systematic review. This requires a formal risk of bias or quality assessment tool. Many tools are available,…

Workshop Introducing the risk of bias tool for non-randomized studies

2014 Hyderabad
Sterne, Reeves, Shea, Savovic, Higgins, Turner
Objectives: To introduce ACROBAT-NRS, the new risk of bias tool for non-randomized studies (NRS), to those who may use Cochrane intervention reviews, and to obtain feedback. Description: It is sometimes appropriate to include NRS in reviews, but the existing risk of bias tool is applicable…

Workshop Introduction to meta-analysis 1: basic ideas for novices

2014 Hyderabad
Beyene
Objectives: The Cochrane Statistics Methods Group has developed a series of workshops addressing statistical guidelines as formulated in the Cochrane Handbook for Systematic Reviews of Interventions. This workshop will cover the basic ideas of meta-analysis at an accessible level. Description…

Workshop Introduction to meta-analysis 2: meta-analysis of binary and continuous outcomes

2014 Hyderabad
McKenzie, Efthimiou
Objectives: The Cochrane Statistical Methods Group has developed a series of workshops addressing statistical guidelines as formulated in the Cochrane Handbook for Systematic Reviews of Interventions. This workshop will provide review authors with the knowledge of issues surrounding meta-analysis…

Workshop Introduction to meta-analysis 3: dealing with heterogeneity

2014 Hyderabad
Efthimiou, Mavridis
Objective: The Cochrane Statistical Methods Group has developed a series of workshops addressing statistical guidelines as formulated in the Cochrane Handbook for Systematic Reviews of Interventions. This workshop will provide review authors with the knowledge to understand and investigate…

Workshop Introduction to meta-analysis 4: meta-analysis of time-to-event data

2014 Hyderabad
Nolan, Efthimiou, Trivella
Objectives: Time-to-event data, such as time to death or time to first seizure, are commonly used outcomes in medical research to summarise the length of time taken for a particular event of interest to occur. This workshop will discuss how to undertake a meta-analysis of time-to-event data.…

Workshop Introduction to meta-analysis 5: including non-standard studies and non-standard data

2014 Hyderabad
Beyene, McKenzie
Objective: The Cochrane Statistics Methods Group has developed a series of workshops addressing statistical guidelines as formulated in the Cochrane Handbook for Systematic Reviews of Interventions. This workshop will provide review authors with the knowledge to recognise and address situations…

Workshop Introduction to the Cochrane Register of Studies Online (CRSO)

2014 Hyderabad
Foxlee, Dooley, Salzwedel, Littlewood
Objectives: To introduce Cochrane members to the Cochrane Register of Studies Online (CRSO). This workshop is aimed at anyone who searches in CENTRAL and is open to all Cochrane members. The CRSO is available to any Cochrane members with an Archie login: http://crso.cochrane.org/ Description…

Poster Investigating wish bias and mediating role of drug dose in Cochrane systematic reviews: the case-example of fluoxetine

2014 Hyderabad
Purgato, Barbui
Background: Some literature reviews have demonstrated that trial design characteristics - such as sponsorship, type of comparison and intervention dose - may influence randomized controlled trials (RCTs) results. In psychiatry, there are examples of studies investigating the role of these…

Poster Is the definition of 'Cochrane consumer' well understood by the public for non-English speaking countries? Challenges and barriers in China

2014 Hyderabad
Jia, Zhang, Mao, Zhang
Background: The Cochrane Consumer Network (CCNet) has always referred to its members as 'consumers' who are patients, family members, and patient advocates. However, little is known about how the term 'Cochrane consumer' is understood by people in non-English speaking…

Poster Keeping up with the evidence: prioritizing systematic reviews on antiangiogenic therapy for age-related macular degeneration

2014 Hyderabad
Lindsley, Virgili, Bacherini, Dickersin, Li
Background: Treatment for age-related macular degeneration (AMD) has been revolutionized in the past 20 years with the introduction of anti-vascular endothelial growth factor (anti-VEGF) therapies. The field is fast-moving with an information overload in the medical literature. Objectives:…

Poster Lack of originality in non-Cochrane systematic reviews

2014 Hyderabad
Fusco, Saldanha, Gresham, Li
Background: Lack of originality in biomedical literature is most problematic when there is substantial unattributed identical text. The standardized format of systematic reviews (SRs) may put them at higher risk for this. Objective: To evaluate lack of originality in non-Cochrane SRs and…