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Displaying 161 - 180 of 651 records Index

Oral Developing core competencies for scientific editors of biomedical journals

2015 Vienna
Galipeau, Moher, Shamseer, Barbour, Bell-Syer, Cumpston, Deeks, Garner, MacLehose, Straus, Tugwell, Wager, Winker
Background: Scientific editors play a key role in the assessment, acceptance, and dissemination of high quality reports of medical research. However, as a group they are generally not well educated in their position. This may be, in part, due to a lack of evidence of what makes a good scientific…

Poster Developing optimal search strategies for retrieval of clinical trials in LILACS database

2015 Vienna
Conceição, Pinto, Conceição
Background: The inclusion of LILACS (Latin American and Caribbean Health Sciences Literature database) in a search for clinical trials is important to identify studies not included in other major bibliographic databases such as MEDLINE or EMBASE. The identification of clinical trials in LILACS is a…

Poster Development and evaluation of doktormitSDM, an approach to improving SDM in daily clinical practice – a continuum of increasing evidence

2015 Vienna
Kasper, Liethmann, Klemperer, Rumpsfeld, Geiger
Background: Proven training of health professionals’ in shared decision making (SDM) competencies are rare. Sound evaluation requires consideration of such measures’ complex character. Objectives: We aim to structure our reporting on a series of studies to develop short in situ training for…

Oral Development and validation of a questionnaire to measure people’s ability to assess claims about treatment effects (CLAIM)

2015 Vienna
Austvoll-Dahlgren, Oxman, Chalmers, Semakula, Nsangi, Guttersrud
Objective: People are confronted with claims about the effects of treatments and health policies daily. There is little current evidence available that describes people’s ability to assess claims about treatment effects and there is no instrument available to measure this. We are developing such an…

Oral Development of a checklist to assess implementation (Ch-IMP) in systematic reviews: the case of provider-based programs targeting children and youth

2015 Vienna
Cargo, Stankov, Thomas, Saini, Rogers, Mayo-Wilson, Hannes
Background: Information on implementation is required in systematic effectiveness reviews to facilitate the translation and uptake of evidence. To capture whether and how implementation is assessed in reviews a checklist for implementation (Ch-IMP) was developed and piloted in a cohort of…

Oral Development of a core outcome set for infant colic

2015 Vienna
Steutel, Korterink, Benninga, Langendam, Tabbers
Background and objectives: Infant colic (IC) is a common problem with a worldwide prevalence of 5% to 25%. This self-limiting disorder can have negative long-term consequences. So far, its etiology remains unknown, resulting in a wide variety in interventions. A previous study showed heterogeneous…

Oral Development of a unified database based on CDISC for individual patient data (IPD) analysis: practices in reproductive health survey

2015 Vienna
Zhang, Fei, Li, Liu
Background: IPD meta-analysis is suggested as the least biased method, which might provide more detailed and reliable conclusions than conventional meta-analysis. Since the original data from individual studies can be re-categorized, IPD meta-analysis can provide more consistent results. Before…

Oral Development of a useful system for grading of recommendations and its application on the Korean Guideline

2015 Vienna
Jang, Shin, Yeon, Chang, Kim, Lee
Background: To alleviate discrepancies between evidence and practice, the Korean Modified Grading of Recommendations Assessment, Development and Evaluation (GRADE) system has been developed and applied to clinical practice guideline on diabetes mellitus. Objectives: To review the determinants for…

Poster Development of an algorithm for choosing study designs

2015 Vienna
Peinemann, Kleijnen
Background: The purpose of systematic reviews is to answer distinct research questions on healthcare interventions. The type of study design, which is scheduled for inclusion in a systematic review, may be critical for its findings and consequences. We did not find an existing algorithm providing…

Oral Development of an objectively derived and validated search strategy to retrieve overviews of systematic reviews in MEDLINE

2015 Vienna
Lunny, McKenzie, McDonald
Background: There has been a steady increase in the number of overviews of systematic reviews published in the last 15 years. The ability to identify published overviews efficiently is of importance to users of evidence syntheses, as well as to researchers interested in investigating their methods…

Poster Development of clinical research support system for conditional coverage with evidence development

2015 Vienna
Son, Park, Lee, Lee, Lee, Yun, Lim
Background: Since 2014, the Korean government has introduced Selective Reimbursement System to intensify national health coverage for severe diseases including cancer, cardiac, cerebrovascular, and rare diseases. Unfortunately, in most cases, available scientific evidence that can be used as an…

Poster Development of the first Academic League of Evidence-based Medicine in Brazil. A partnership between the Brazilian Cochrane Centre and Universidade Federal de São Paulo

2015 Vienna
Daou, Atallah, Barroso, Costa, Paroni, Freitas, Vitor, Viel, Klepp, Baldan, Martins, de Mello, Gomes, Fonseca, Gomes, Protetti, Hungria, Porfirio, Gois, Riera
Background: The relationship between Universidade Federal de São Paulo and the Brazilian Cochrane Centre (BBC), which has some members as professors in the Institution, made possible the development of the first Academic League of Evidence-Based Medicine (EBML) in Brazil. Objectives: The objective…

Workshop Diagnostic test accuracy reviews: advanced meta-analysis - dealing with heterogeneity and test comparisons

2015 Vienna
Macaskill, Takwoingi
Objectives: 1. To explain the recommended statistical models used for diagnostic test accuracy (DTA) meta-analysis and the concepts underlying these methods. 2. To illustrate the methods and their interpretation using examples. Description: This workshop will cover advanced statistical…

Poster Differences in the characteristics of exclusions in randomised trials based on the type of the intention-to-treat reporting

2015 Vienna
Cozzolino, Abraha, Orso, Lombardo, Cirocchi, Cherubini, Rimland, Germani, Marchesi, Eusebi, Montedori
Background: Randomised trials that deviate from intention-to-treat approach are often encountered in meta-analyses. This type of trial also is more likely to report exclusions than trials that declare standard intention-to-treat. Objectives: To assess differences in the types and the…

Poster Different mortality time-points in critical care trials: current practice and influence on effect estimates

2015 Vienna
Roth, Heidinger, Havel, Arrich, Gamper, Herkner
Background: Mortality is frequently used as a primary outcome in critical care trials. It is a patient-orientated variable and robust against information bias. Mortality incidence however needs to be measured at a defined time-point. Practice of meta-analysis in critical care shows that follow-up…

Poster Difficulty in combining results of primary studies in the addiction field: need to enhance consistency of reported outcomes

2015 Vienna
Minozzi, Mitrova, Saulle, De Crescenzo, Amato
Background: The COMET initiative outlined the need for the development and application of standardized sets of outcomes agreed by all stakeholders, including patients, known as a ‘core outcome set’. In order to allow the results of trials to be compared, contrasted and combined as appropriate, the…

Oral Discernment of academic conflicts of interest for Cochrane Systematic Reviews

2015 Vienna
Miyazaki, Ota, Mori, Sasaki, Kirkham, Dwan
Background: Cochrane has set a ground policy to ensure that its systematic reviews are free of conflict of interest (COI) and to prevent potential influence from commercial sponsors or sources. Although Cochrane’s declaration of interest focuses largely on avoiding potential financial COI, guidance…

Poster Discrepancies in 'evidence-based' practice guidelines for diagnostic lumbar discography

2015 Vienna
Hegmann, Ott, Effiong, Thiese, Harris
Background: Discography attempts to determine whether chronic back pain is caused by disc pathology. A needle is inserted into discs and an X-ray dye is injected with imaging. Positive test results involve reproduction and/or augmentation of the patient’s pain. However, as this procedure is fairly…

Oral Discrepancies in outcome reporting exist between protocols and published oral health Cochrane Reviews

2015 Vienna
Pandis, Fleming, Worthington, Dwan, Salanti
Background: In systematic reviews, selective reporting may develop for a variety of reasons, for example, due to the use of multiple measurement scales, outcomes or time points and selective inclusion of specific outcomes. There is paucity of information on selective reporting based on comparisons…

Poster Discussing the risks and benefits of opioid use for chronic non-cancer pain (CNCP)

2015 Vienna
Harris
Background: The use of opioids for chronic non-cancer pain (CNCP) has increased rapidly in the last 15 years. However, the effectiveness of opioids for CNCP remains unsupported by good quality evidence, and adverse effects on multiple organ systems are increasingly documented. Opioids are often…