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Oral A new strategy for meta-analysis of continuous covariates in observational studies
2011 Madrid
Sauerbrei, Royston
Background: Assessing the effect of a continuous covariate in a single study requires the determination of a dose-response relationship in a model adjusting for other covariates. Even with individual patient data (IPD), summarizing the results of several dose-response functions in a meta-analysis…
Poster A novel approach to building evidence for improving communication about childhood vaccinations in low- and middle-income countries: the 'communicate to vaccinate’ (COMMVAC) project
2011 Madrid
Lewin, Hill, Kaufman, Galak, Kis-Rigo, Anderson, Bosch-Capblanch, Hussein, Lin, Mahomed, Rhoda, Robinson, ben Saude de Castro Freire, Waggie, Wiysonge
Background: Effective provider-parent communication can improve childhood vaccination uptake and strengthen immunization services in low- and middle-income countries (LMICs). However, demand-side interventions to improve vaccination uptake have been neglected and existing rigorous research is often…
Oral A novel approach to evaluate the diagnostic accuracy of a sequence of tests
2011 Madrid
Novielli, Cooper, Abrams, Sutton
Background: One diagnostic test is rarely sufficient to complete a diagnosis. Despite this, most diagnostic accuracy studies focus on the evaluation of an individual test, and therefore approaches for the meta-analysis of this diagnostic literature have also focused exclusively on estimating the…
Poster A pilot Mixed Methods Appraisal Tool (MMAT) for systematic mixed studies reviews
2011 Madrid
Pluye, Cargo, Robert, Bartlett, O’Cathain, Griffiths, Boardman, Gagnon, Rousseau
Background: A new form of literature review has emerged, mixed studies review. These reviews include qualitative, quantitative and mixed methods studies. The Mixed Methods Appraisal Tool (MMAT) is intended to be used as a critical appraisal tool for systematic mixed studies reviews (SMSRs). In…
Oral A pilot study of an evidence-based practice training program for Filipino physiotherapists: emerging evidence on outcomes and acceptability
2011 Madrid
Dizon, Grimmer-Somers, Kumar
Background: Evidence-based practice (EBP) has been challenging for health professionals across the globe. Issues of implementing the evidence become even more challenging among health professionals in developing countries, due to cultural and contextual issues which compound the existing barriers…
Poster A rapid systematic review versus a Cochrane systematic review: An empirical comparison
2011 Madrid
Rizzo, Llewellyn, Martin
Background: There is increased pressure to conduct systematic reviews as comprehensively as possible within the constraints of a timescale that meets the needs of policy makers.
Objectives: We aimed to evaluate how the findings and conclusions of a full Cochrane systematic review differ when…
Poster A snowballing technique to ensure comprehensiveness of search for systematic reviews: A case study
2011 Madrid
Vedula, Mahendraratnam, Rutkow, Kaufmann, Rosman, Twose, Dickersin
Background: Increasingly, trial data are becoming available through internal company documents made accessible through litigation. We performed a systematic review of how such documents had been used in the past and how they were identified. Systematic reviews, such as ours, that address complex…
Poster A survey analysis of patient for patient safety in China
2011 Madrid
Zhang, Li, Zhang, Yin, Shang, Wei, Zhang
Background: Patient safety involves not only medical institutions and medical workers but also patients. Much research has been done to promote patient involvement in patient safety recently. But very little is known of this area in China.
Objectives: To investigate the knowledge, attitudes and…
Poster A survey of searching CBM and LILACS databases in Cochrane Systematic Reviews
2011 Madrid
Chen, Yao, Wang, Liang, Liang
Background: Ideally, unbiased systematic reviews should always search and include all relevant trials, independent of the language of publication. The inclusion of studies published in languages other than English could help avoid bias. The Cochrane Handbook recommends systematic reviewers to…
Poster A survey of the awareness rate of GRADE in China
2011 Madrid
Chen, Yang, Wang, Yao, Wang
Background: Evidence based medicine and systematic reviews are becoming better known among clinicians, researchers and policy-makers; it is imperative to promote the development of GRADE in China. Although it has been ten years since the GRADE system first emerged, it is still a relatively new…
Poster A systematic review identifies substantial heterogeneity of studies evaluating effects of rural-to-urban migration on cardiovascular risk factors in low and middle income countries
2011 Madrid
Hernandez, Pasupuleti, Deshpande, Bernabe-Ortiz, Miranda
Background: Limited information is available about the effects of rural-to-urban within-country migration on cardiovascular (CV) risk factors in low and middle income countries (LMIC).
Objectives: We performed a systematic review of studies evaluating these effects and having rural and/or urban…
Oral A systematic review of studies that develop or evaluate search filters for the retrieval of diagnostic studies in MEDLINE
2011 Madrid
Beynon, Leeflang, Eisinga, McDonald, Mitchell, Whiting, Glanville
Background: Search filters are developed to improve the efficiency and effectiveness of searching and are created by identifying and combining search terms to retrieve records with a common feature (e.g. diagnostic accuracy).
Objectives: To determine whether any existing methodological search…
Poster A systematic review of the quality and types of instruments used to assess KTE implementation and impact
2011 Madrid
Irvin, Cole, Keown, Kramer, Brenneman Gibson, Kazman Kohn, Mahood, Slack, Amick III, Phipps, Garcia, Morassaei
Background: Knowledge transfer and exchange (KTE) is a burgeoning practice at research organizations worldwide. However the effective- ness of KTE practices has not been routinely/consistently evaluated. The need for such evaluation has been voiced (Lavis et al, 2003; Eccles et al, 2005). One…
Poster A systematic review on the efficacy of statins in animal model
2011 Madrid
Pecoraro, Moja, Dall’Olmo, Cappellini, Liberati, Garattini
Background: Statins are recognised as an effective treatment for lowering cholesterol levels and reducing the risk of cardiovascular diseases. They have been widely studied in basic and human research and there are no systematic reviews of statins across animal models.
Objectives: We explored…
Poster A tool to improve efficiency and quality in the production of protocols for Cochrane Reviews of Diagnostic Test Accuracy
2011 Madrid
Pennant, Wisniewski, Hyde, Davenport, Deeks, on behalf of the Cochrane DTA
Background: The Cochrane Diagnostic Test Accuracy Editorial Team (DTA ET) organises methodological peer review of DTA protocols and reviews. In the first part of this process, submitted protocols are sent for peer review by DTA statisticians, search specialists and clinical epidemiologists, and…
Poster A worked example of 'bestfit’ framework synthesis: A potentially more consistent or reliable form of qualitative data synthesis?
2011 Madrid
Booth, Cooper
Background: A variety of different approaches to the synthesis of qualitative data are advocated in the literature, but none is recognised as the preferred method.
Objectives: To describe the application of a pragmatic 'best fit’ framework synthesis approach to qualitative evidence synthesis…
Poster Access alone does not guarantee use: The need for training to use evidence based resources
2011 Madrid
Sriganesh
Background: In the last few years, access to evidence based resources has increased in developing countries. However there is not a proportional increase in the qualitative and quantitative use of such resources.
Observation: As information professionals helping health professionals in a…
Poster Access to The Cochrane Library: Results of Canada’s National Pilot License Initiative
2011 Madrid
Squires, Grimshaw, Schaafsma
Background: The Cochrane Library is one of the most reliable sources of health information about 'what works’ in healthcare. Yet access in Canada is limited; approximately 10% of Canadians have access to The Cochrane Library. In response, a national pilot license was instituted that gave all…
Poster Access to ongoing paediatric drug trials in the Netherlands
2011 Madrid
Hooft, Weber, Hamelinck, Offringa
Background: As the number of paediatric clinical trials increases it is essential that their existence is publicly documented and that eventually their results will be made publicly available. Registering clinical trials can bring us one step closer to an unbiased and efficient clinical world.…
Poster Accuracy of the MeSH term 'Breast Neoplasms': Ten years on
2011 Madrid
Tai, Willson, Ghersi
Background: MeSH terms are designed to categorise articles into topic areas which allows us to search with some degree of specificity. In 1999, we analysed whether the MeSH term 'Breast Neoplasms' was correctly assigned to records in MEDLINE. We found that the MeSH term was accurately…