Displaying 1 - 20 of 108 Index

Oral 50 Years of randomised controlled trials relevant to the care of schizophrenia: 2000 studies, 18 outcomes, 670 rating scales

1998 Baltimore

Thomley, Adams, Adams

Introduction/Objective: The Cochrane Schizophrenia Group (CSG) has constructed a comprehensive register of trials relating to the care of those with schizophrenia or unspecified chronic/serious mental illnesses. The MRC UK supported a detailed survey of the first 2000 controlled trials on this…

Oral 50 Years of reporting of randomised controlled trials in general health care journals worldwide: how things have changed

1998 Baltimore

McDonald, Clarke

Introduction/Objective: To investigate reporting of randomised controlled trials (RCTs) in general health care journals over the last 50 years, with particular reference to the distribution and size of RCTs over time. Methods: One general health care journal, (usually that of the national medical…

Poster A World Wide Web interface for the UKCCCR Register Of Cancer Trials

1998 Baltimore

Brown, Grosse, Jenkin, Stewart, Fayers

Introduction: The UKCCCR Register of Cancer Trials is a database of United Kingdom Randomised Controlled Trials (RCTs) in cancer. The UKCCCR Register provides information for those considering participation in RCTs, helps funding bodies assess the relevance of proposals for new trials and…

Poster A challenge to accepted wisdom: systematic review of 35 Years of cholera vaccine trials

1998 Baltimore

Graves, Deeks, Demicheli, Pratt, Jefferson

Cholera killed whole-cell (KWC) vaccines have been discouraged since the 1970s in either endemic or epidemic areas on the grounds that they have low efficacy or short duration of efficacy (3-6 months), require multiple doses, and are less effective in children under five than in adults. Significant…

Poster A comparison of checked versus unchecked individual patient data (IPD)

1998 Baltimore

Burdett, Stewart

Introduction/Objectives: IPD meta-analyses (MAs) of randomised controlled trials (RCTs) usually involve detailed data checking. This can be done at different levels, from simply finding and querying missing or inconsistent data, to detailed investigation of the integrity of the randomisation and…

Poster A multifile search of five bibliographic databases for stroke trials

1998 Baltimore

Thomas, Gubitz, Mclnnes, Krabshuis, Counsell

Introduction/Objective: Electronic searching of the many available bibliographic databases is an important means of trial identification, offering quick access to many thousands of references. However, such searching is time consuming and can be expensive: complex database-specific searches need to…

Poster A pilot project to create partnerships between academic and professional organizations to produce and disseminate systematic reviews

1998 Baltimore

Hayward, Hammond, Hebert

Introduction/Objective: In 1997, the Dissemination Program of the Alberta Heritage Foundation for Medical Research in Edmonton, Canada, initiated a project to produce and disseminate systematic reviews in partnership with three health professional associations, a consumers' association and…

Oral A randomized trial of the preference of gastroenterologists for a Cochrane review versus traditional reviews

1998 Baltimore

McDonald, Mahon, Zamke, Feagan, Simms

Introduction/Objective: To assess gastroenterologists' preferences for a Cochrane review versus traditional review material. Methods: Canadian gastroenterologists were randomized into three groups: to receive either the Cochrane review of azathioprine or 6-mercaptopurine for the treatment of…

Poster A systematic review of magnesium sulfate in the treatment of acute exacerbations of asthma

1998 Baltimore

Rowe, Bretzlaff, Bourdon, Bota, Camargo

Introduction/Objective: To determine the effect of intravenous magnesium sulfate for the treatment of patients with acute exacerbations of asthma managed in the emergency department. Methods: Computerised searches were conducted using the Cochrane Airways Review Group "Asthmi and Wheez"…

Poster A systematic review of nedocromil sodium in the prophylactic treatment of exercise-induced bronchoconstriction

1998 Baltimore

Spooner, Saunders, Rowe

Introduction/Objective: To assess the effectiveness and safety of using a single dose of nedocromil sodium (NCS) to prevent exercise-induced bronchoconstriction (EIB). Methods: Computerised searches were conducted using the Cochrane Airways Review Group RCT register, Current Contents, and the CC…

Poster A systematic review of the quality of homeopathic clinical trials

1998 Baltimore

Jonas, Shasha, Anderson, Lyons

Introduction/Objective: To review the quality of clinical trial research in homeopathy and identify the extent of threats to validity of causal interpretations in these trials. In addition, we compared the type and extent of these threats to validity to research on conventional therapies. Methods…

Poster A systematic review on the impact of mass media on health services utilisation

1998 Baltimore

Grilli, Freemantle, Minozzi, Domenighetti, Finer

Introduction/Objective: To review the available evidence on the effect of mass media (radio, TV, newspapers, magazines, leaflets, posters and pamphlets) on health services utilisation. Methods: Unrestricted systematic literature search of experimental and rigorous quasi experimental (interrupted…

Poster Alendronate for prevention and treatment of postmenopausal osteoporosis

1998 Baltimore

Cranney, Welch, Coyle, Adachi, Tugwell, Wells, Otten, Shea, Berthelot, Wolfson, Flanagan

Introduction/Objective: We conducted a Cochrane systematic review to determine the efficacy of alendronate therapy at preventing bone loss and fractures in postmenopausal women. These results are being incorporated into a cost-effectiveness analysis of alendronate compared to hormone replacement…

Poster An electronic data repository of randomized controlled trials for the treatment of depressive disorders

1998 Baltimore

Chiquette, Aguilar, Williams, Mulrow, Cornell

Introduction: Systematic reviews depend on a comprehensive data collection of the primary studies. Since multiple reviews in the same field may use data from similar sets of trials, a computerized database of trial summaries would minimize duplication of effort and facilitate timely reviews and…

Poster An evaluation of interventions to reduce the use of tobacco products

1998 Baltimore

Honkins, Briss, Pechacek, Glynn, Fielding

Introduction/Objectives: A national, independent, non-federal organization, the Task Force on Community Preventive Services, is systematically reviewing published evidence on the effectiveness of population-based interventions to reduce the consumption of tobacco products. The Task Force will use…

Poster An interactive hypertext database of synoptic summaries of cardiovascular clinical trials

1998 Baltimore

Cucherat, Boissel, Haugh, Strang, Gueyffier

In cardiology there is a large number of clinical trials and this number increases each year. This makes it not feasible to remember and use all the information without help. A centralized system providing synthetic information for use in clinical pharmacology, evidence-based medicine and teaching…

Poster An quality assurance program evaluating prescription for tardive dyskinesia in French psychiatric hospitals: integration of Cochrane systematic reviews as an evidence-based reference

1998 Baltimore

Amsallem, Lachaux, Haugh, Boissel

Introduction: Neuroleptic-induced tardive dyskinesia is a disabling condition affecting about 20 to 30% of patients taking neuroleptics. In France, the importance of this condition is probably underestimated, and thus we decided to undertake a study of its prevalence, and psychiatrists'…

Poster Another decision to evaluate: choice of standardized mean difference effect size estimator

1998 Baltimore

Cannella

The standardized mean difference is the effect size generally recommended in clinical trials and other studies assessing treatment effects on outcomes measured on a continuous scale. Initially, the standard deviation of the control group, recommended for use in meta-analysis by Glass, was the…

Poster Antidepressants for the treatment of bulimia nervosa (BN)

1998 Baltimore

Bacaltchuk, Hay, Trefiglio, Mari, Hay

Introduction: BN is an eating disorder characterized by uncontrolled compulsive eating binges, followed by recurrent use of self-induced purging as vomiting, laxative abuse, or other inappropriate compensatory methods to prevent weight gain. The prevalence among adolescent and young adult females…

Poster Antidepressants versus psychtherapy for the treatment of bulimia nervosa (BN)

1998 Baltimore

Bacaltchuk, Hay, Trefiglio, Marti, Hay

Introduction: BN is an eating disorder characterized by uncontrolled compulsive eating binges, followed by recurrent use of inadequate compensatory behaviors in order to prevent weight gain. The prevalence among adolescent and young adult females is approximately 1%-3% (APA 1994). Antidepressants…