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Oral Living Evidence to Inform Health Decisions Framework (LE-IHD): A practical interactive framework based tool to guide the incorporation of Living Evidence in the development of knowledge transfer products
2023 London
Rojas-Reyes, Bendersky , Auladell-Rispau, Verdugo, Rada, Alonso-Coello, Urritia
Background: Knowledge transfer [KT] products used to inform health decisions should be based on the most current evidence. A framework based practical tool for incorporating the Living Evidence [LE] model can address this need.
Objectives: To define a framework to guide the incorporation of the…
Poster : Using the Grading of Recommendations, Assessment, Development, and Evaluations approach to report the conclusions in a non-inferiority randomized clinical trial.
2023 London
Seron, Oliveros
Background: Grading of Recommendations Assessment, Development and Evaluation (GRADE) has proposed a system for rating the certainty of a body of evidence (CoE) to determine confidence in the estimate. The GRADE approach has not only refreshed the way in which the evidence is presented, and even…
Poster A Pretrained Language Model for Classification of Cochrane Plain Languages Summaries on Conclusiveness of Recommendations
2023 London
Mijatović, Ursić, Buljan, Marušić
Background: Cochrane Plain Language Summary (PLS) is a stand-alone summary of a Cochrane Review used to disseminate the evidence in health to a non-research audience. They can be categorized according to level of conclusiveness, i.e., whether they contain conclusive recommendations on intervention’…
Poster A Scoping Review of Published and Ongoing Prospective Meta-Analyses in Health Research
2023 London
Love, Li, Sotiropoulos, Williams, Libesman, Hunter, Seidler
Background:
Prospective meta-analyses (PMA) may reduce many of the issues that can occur in retrospective meta-analyses, such as reducing biases in publication and selective outcome reporting. However, common misunderstandings of the PMA methodology remain, leading to inappropriate and/or…
Oral A call to support Cochrane's social responsibility of improving health equity - the Equity Group
2023 London
Parker, Petkovic, Pardo Pardo, Welch, Tugwell
Background:
Health equity is a moral and ethical imperative. In the 2022 Cochrane Lecture, Jimmy Volmink challenged the organization to address not only inequities raised from health interventions but also consider how to address the social determinants of health which lead to such disparities.…
Poster A co-produced e-toolkit to support patient and public involvement in developing and promoting core outcome sets
2023 London
Barrington, Harman, Turner, Smith, Williamson, Young
Background: This work links to the international Core Outcome Measures in Effectiveness Trials (COMET) Initiative. Core Outcome Sets (COS) can reduce research waste by promoting consistency in outcome reporting. Over 400 COS have been published; another 300 COS are in development. COS should be…
Oral A comparison of different forward citation chasing tools for complementary searches for Cochrane systematic reviews
2023 London
Bracchiglione, Requeijo, Santero, Savall, Selva, Samsó, Roqué-Figuls, Escobar Liquitay, Solà
Background: Forward citation chasing, defined as the use of a citation index to retrieve references that cite a source, is currently recommended as a complement to find all possibly relevant research for systematic reviews (SRs). Recently, new tools have been developed to ease this task, but their…
Poster A comparison of duplicate detection automation tools: a head-to-head comparison study
2023 London
Clark, Bateup , Fulbright , Forbes, Gruber , Hair , Qureshi, Stansfield , Steel , Thomas
Background:
A key task when conducting a systematic review is to identify and remove duplicate records retrieved by a literature search across multiple databases, a process referred to as deduplication. Deduplication is time-consuming and error prone, particularly when processing thousands of…
Poster A comparison of two search filters for economic evaluations. The CADTH Narrow vs the NHS EED search filter
2023 London
Moberg, Berg, Eriksson, Lundqvist, Wiss, Ringborg
Objectives:
The aim of this project was to evaluate if the CADTH narrow economic search filter (CADTH narrow) could produce a similar sensitivity to the NHS EED search filter (NHS EED) while achieving a lower number needed to read (NNR) when searching for economic evaluations in the Ovid MEDLINE…
Poster A comprehensive approach to assess the existing evidence and appropriateness of anticancer drugs on advanced cancer: the ASTAC project
2023 London
Bracchiglione, Santero, Salazar, Rodríguez-Grijalva, Requeijo, Meade, Selva, Savall, Merchan, Cantero, Hernández, Meza, Acosta-Dighero, Quintana, Bonfill
Background: Appropriateness of Systemic Treatments for Advanced Cancers (ASTAC) is a collaborative research project aiming to assess the appropriateness of anticancer drugs in advanced digestive non-intestinal cancers (ADNIC), contributing to reduce potential scenarios of misuse.
Objective: To…
Poster A conceptual framework of evidence synthesis for using real-world data to improve childhood cancer health outcomes and resource use in Egypt
2023 London
Soliman
Background: Given the large number of children with cancer in Egypt, the limited resources, and the inferior survival outcomes, there is an urgent need to better utilise available resources to improve care and outcomes efficiently based on evidence. However, there is a gap in knowledge about…
Oral A critical appraisal tool for systematic reviews of patient-reported outcome measures
2023 London
Lei, Xiong, Wang, Li, Norris, Chen
Background:
Systematic reviews (SRs) of patient-reported outcome measures (PROMs) are an important way to select the appropriate PROMs. High-quality SRs can provide a comprehensive overview of the PROMs and provide evidence-based recommendations for pediatricians. However, because the risk of bias…
Poster A critical historical review shows mismatch between available evidence and related international guidelines recommendations: the case of advanced oesophageal cancer
2023 London
Santero, Savall Esteve, Bracchiglione, Requeijo, Bonfill Cosp
Background: In the case of advanced oesophageal cancer (AOC) patients, whose prognosis is very poor, most clinical practice guidelines (CPGs) recommend the use of anticancer drugs over best supportive care (BSC) alone, but these recommendations may not have taken into account all the available…
Poster A cross-sectional analysis of the use of data visualisation in scoping reviews and evidence maps
2023 London
South, Rodgers
Background
Scoping reviews are well-suited to visually presenting data due to their focus on mapping evidence. A wide range of data visualisation methods and tools are available to researchers, including tools to create interactive data visualisations. Interactive data visualisation allows easy…
Poster A descriptive analysis of funding in research articles published in Revista médica de Chile between 2017-2021.
2023 London
Flores, Briceño, Morales, Cabrera, Villagran, Grandi, Riva, Cruzat, Garnham, Meza, Madrid, Bracchiglione
Background: Revista Médica de Chile (RMC) is the oldest Chilean journal of medical science. It is responsible for publishing original articles monthly which include a broad spectrum of the medical fields and receive papers from different countries. It is the Chilean journal of health science with…
Oral A digital map of systematic reviews on non-pharmacological interventions to inform policy making in infectious disease control
2023 London
Wilbe Ramsay, Edebert, Palmquist Wojda, Östlund
Background: The COVID-19 pandemic accentuated the need for comprehensive evidence synthesis to guide decisions regarding infection disease control and preparedness. In Sweden, an investigator was tasked by the government with reviewing the Infection Control Act and analyzing the need for new…
Workshop A hands-on introduction to NMAstudio: a web-application to produce and visualize network meta-analyses
2023 London
Chaimani, Yu, Metelli
Background: Evaluation of network meta-analysis (NMA) evidence can be challenging and time-consuming, especially when dealing with large networks of interventions. Despite the fact that NMAs are increasingly adopted to inform decision-making, the lack of user-friendly software is still limiting…
Oral A living network meta-analysis of treatments for rheumatoid arthritis: Novelty at the frontier of living evidence
2023 London
Whittle, Thomas, Mujaab Kamso, Pardo Pardo, Buchbinder, Hazlewood
Background: Choosing between the many effective disease-modifying therapies (DMARDs) for rheumatoid arthritis requires timely, high-quality systematic review of the best available evidence. ‘Living’ systematic reviews fast-track evidence synthesis without compromising rigorous systematic review…
Poster A method for quantifying the generalizability of meta-analysis results in clinical practice: meta-epidemiologic cohort study approach with three eye-opening examples
2023 London
Merrelaar, Schwameis, Buchtele, Titz, Kienbacher, Warenits, Boegl, Lipa, Arrich, Herkner
Background: The generalizability and applicability of meta-analyses from randomized controlled trials (RCTs) is often discussed and is part of the GRADE assessment.
Objective: Our aim was to quantify generalizability using three prominent evidence syntheses from the field of critical care and…
Oral A method for the rapid assessment of high-cost cancer drug indications in a hospital setting
2023 London
González-Browne, Carreño-Leiton, Muñoz-Montecinos, Maza, Lahoz, Ferrer-Rosende, Nájera-De Ferrari , Quirland-Lazo
Background:
Hospitals are usually the entry point of new technologies. Facing the challenge posed by the growing costs of cancer drugs, there is a need for healthcare providers to articulate systematic and timely formulary decision-making processes considering not only the efficacy and safety of…