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Displaying 81 - 100 of 10301 records Index
Workshop Assessing risk of bias in nonrandomized studies of interventions: introduction to the ROBINS-I tool
2024 Prague [Global Evidence Summit]
Savovic, Waddington, Whiting
Oral Assessing success of guideline implementation: development of a generalized tool facilitating cross-comparison and targeted improvement
2024 Prague [Global Evidence Summit]
He, Huang, Huang, Li, Wang, Yang, Yi, Zeng, Zhang, Zhang, Zou
Background: Many evidence-based clinical practice guidelines fail to translate to improvement of daily health care practice and patient health outcomes. However, benchmarking and comparison between guidelines, institutions, and regions and targeted interventions are usually not feasible due to a…
Poster Assessing the Current Landscape of Health Technology Assessment Knowledge and Skills Among Clinicians in Croatia
2024 Prague [Global Evidence Summit]
Bralić , Vuković, Krznarić, Znaor, Huić, Marušić
"Background: Health technology assessment (HTA) will become mandatory across the EU starting January 2025, aiming to evaluate the clinical, economic, ethical, and societal implications of healthcare interventions. However, controversies exist regarding the feasibility and capacity for…
Poster Assessing the Effectiveness and Safety of Deep Brain Stimulation in Severe and Refractory Obsessive-Compulsive Disorder: A Living Systematic Review
2024 Prague [Global Evidence Summit]
Gómez, Triñanes Pego, Puñal-Riobóo, María del Carmen, Verdugo, Auladell-Rispau, Rojas-Reyes, Faraldo-Vallés
Background: Deep brain stimulation (DBS) has emerged as a potential treatment for refractory obsessive-compulsive disorder (OCD). However, the current evidence regarding its effectiveness and safety remains inconclusive.
Objectives: This Living Evidence Synthesis aims to provide a timely, rigorous…
Oral Assessing the Risk of Bias in Randomised Controlled Trials with Large Language Models: A Feasibility Study
2024 Prague [Global Evidence Summit]
Lai, Ge, Talukdar, Estill
Background
Large language models (LLMs) may facilitate the labour-intensive process of systematic reviews.
Objective
To explore the feasibility and reliability of utilizing LLMs to assess risk of bias (ROB) in randomised controlled trials (RCTs).
Methods
We conducted a pilot and feasibility study…
Poster Assessing the Risk of Bias in Randomized Controlled Trials using RoB2 by Large Language Models: A Feasibility Study
2024 Prague [Global Evidence Summit]
Huang, Lai, Pan, Ge, Ge
Background: The revised version of the risk of bias tool (RoB2) overcomes some original limitations, but concurrently introduces challenges in its application. Large language models (LLMs) may potentially assist the utilization of RoB2. However, the exact methods and reliability remain uncertain.…
Oral Assessing the availability, scope, and quality of stroke rehabilitation guidelines in LMICs - a systematic review of quality and scope
2024 Prague [Global Evidence Summit]
Chawla, D’souza, Demers, Gandhi, Hombali, Kamalakann, Mahmood, Montanaro, Ngeh, Sebastian, Solomon, Urimubenshi
Background: A significant amount of the stroke burden globally is borne by low- and middle-income countries (LMICs). However, efforts toward reducing the stroke burden in this context have faced immense challenges. One reason is because of the scope and quality of clinical practice guidelines (CPGs…
Poster Assessing the certainty of evidence in studies about peoples’ values, utilities, or the importance of outcomes
2024 Prague [Global Evidence Summit]
Karam, Zhang, Alonso-Coello, Brozek, Schünemann
Oral Assessing the effectiveness of artificial intelligence tools in automating systematic reviews for cancer research: a systematic review
2024 Prague [Global Evidence Summit]
Kumar, Miranda, Saha, Su, Sussman, Yao
Background:
Systematic reviews (SRs) play a crucial role in evidence-based medicine, offering guidance to clinicians to further improve patients’ outcomes. However, the time required for completing SRs, averaging around 67.3 weeks, poses a significant challenge. A literature search, particularly in…
Oral Assessing the impact of diverse definitions of major adverse cardiac events on coronary stent study outcomes
2024 Prague [Global Evidence Summit]
Du, Jin, Liao, Lin, Long, Wang
Background: Composite end points like major adverse cardiac events (MACEs) are extensively used in coronary stent research despite varied definitions. These end points, combining safety and efficacy indicators, complicate result interpretation.
Objectives: This study evaluates the impact of MACE…
Poster Assessing the richness and thickness of data in primary qualitative research included in qualitative evidence synthesis
2024 Prague [Global Evidence Summit]
Ames, Noyes, France, Bianchim, Cooper, Silveira Bianchim
Poster Assessing transparency and reproducibility practices in dental randomized controlled trials
2024 Prague [Global Evidence Summit]
Onofre, Prado, Dotto, Bernardo
Background: Evidence about transparency and reproducibility practices is scarce in dentistry.
Objectives: To evaluate transparency and reproducibility practices in randomized controlled trials (RCTs) in dentistry.
Methods: This meta-research study included RCTs in dentistry regardless of topic,…
Oral Assessment of Soil-Transmitted Helminths Among School-Aged Children (5-18 Years) in Low- to Middle-Income Nations: A Systematic Review and Meta-Analysis
2024 Prague [Global Evidence Summit]
Kanungo, Palo, Kshatri, Agrawal, Pattnaik, Mandal, BHATTACHARYA, Pati, Pati
Background: The Global Burden of Disease (GBD) 2019 report revealed alarming statistics regarding soil-transmitted helminths (STHs), with 1.5 million disability-adjusted life years (DALYs) lost due to STH-related issues, while a staggering 5.9 million individuals remain susceptible to STH…
Poster Assessment of publication time and Review process in Campbell Systematic Reviews
2024 Prague [Global Evidence Summit]
Pan, Pan, Yang, Yang
Background: Delayed publication of systematic reviews results in a risk of outdated data. There are no studies to examine the time and review process from title registration and publication of the protocol for a Campbell systematic review to publication of the Campbell systematic review till now.…
Oral Assessment of reporting of stroke clinical practice guidelines in low- and medium-income countries using the RIGHT checklist: a scoping review
2024 Prague [Global Evidence Summit]
Ako, Ako, Davies-otto, Davies-otto, Ngeh, Ngeh, Ngeh, Ngwe, Ngwe, Wiysahyuy, Wiysahyuy
Background
Clinical practice guidelines (CPGs) are crucial in health care because they directly provide recommendations to clinicians and decision-makers. High-quality CPGs can improve health care decisions and outcomes when they are rigorously developed and reported. Low- and medium-income…
Poster Assessment of the GRADE domain “publication bias” in recent Cochrane reviews: a cross-sectional study
2024 Prague [Global Evidence Summit]
Stegeman, Toews, Bruschettini, Minozzi, Cinquini, Färnqvist, Meerpohl, Toews
Background
There is evidence that around 50% of all studies remain unpublished and the resulting bias due to missing evidence is observed to impact on various research fields and topics. Approaches for assessing bias due to missing evidence are advancing as reflected in the Cochrane Handbook and,…
Oral Assessment of the quality of recommendations in high-quality methodological clinical practice guidelines for mental health care and epilepsy in pregnancy
2024 Prague [Global Evidence Summit]
dos Santos, Gabriel, Stein, De Melo
Background: The treatment of mental disorders and epilepsy during the gestational period provokes concern about the risks and benefits. Clinical Practice Guidelines (CPGs) are documents that should support decisions, presenting recommendations formulated based on the best available evidence and…
Poster Assigning GRADE levels in an overview of reviews using general principles identified from current GRADE guidelines.
2024 Prague [Global Evidence Summit]
Dullea, O'Sullivan, O'Brien, Harrington, Carrigan, Ahem, McGarry, Walsh, Clyne, Smith, Ryan
Background:
Existing guidelines on the conduct of overviews of reviews and umbrella reviews recommend an assessment of the certainty of evidence, but provide limited guidance on ‘how to’ apply Grading of Recommendations Assessment, Development and Evaluation (GRADE) to such a complex evidence…
Poster Assisting Recommendations Formulation of Practice Guideline with Large Language Models: A Feasibility Study
2024 Prague [Global Evidence Summit]
Ye, Ge
Background Formulating recommendations in developing practice guidelines involves complex and rigorous processes. Therefore, more resources and expertise are needed. Artificial intelligence (AI) is promising in accelerating the guideline development process. This study aims to assess the…
Poster Association between insomnia drugs and adverse events in adults: a systematic review and network meta-analysis
2024 Prague [Global Evidence Summit]
Pan
Background: The clinical decision-making to insomnia drugs should comprehensively weight its risks.
Objective: To perform a systematic review and network meta-analysis of randomized controlled trials to compare the AEs associated with different insomnia drugs for adults with insomnia.
Methods: We…