• Trends in use and costs of lumbar and full spine radiography by chiropractors in Ontario: a review of Ontario Health Insurance Plan and Workplace Safety and Insurance Board data from 1994 to 2001
• Trends over time in the size and quality of randomised controlled trials of interventions for chronic low-back pain
• TRiads-P: A translational research programme to promote evidence-based practice in the community pharmacy setting
• Trial Characteristics and Treatment Effect Estimates in Randomized Controlled Trials of Chinese Herbal Medicine: A Meta-Epidemiological Study
• Trial data available in FDA and EMA reports: a cross-sectional study
• Trial investigators as authors of Cochrane reviews: do we manage conflicts of interests adequately?
• Trial publication after registration in Clinical Trials Registry of India (CTRI): a cross-sectional analysis of randomized controlled trials
• Trial Registers: What Do Users Really Really Want?
• Trial registration can be a useful source of information for quality assessment: a study of trials records retrieved from the WHO search portal
• Trial results in clinical trial registries – towards more transparency in clinical research
• Trial sequential analyses of 145 Cochrane Neonatal Group meta-analyses considering adequacy of allocation concealment and heterogeneity
• Trial sequential analyses of meta-analyses from a Cochrane review of targeting intensive versus conventional glycaemic control in patients with type 2 diabetes
• Trial sequential analyses of six Cochrane neonatal group meta-analyses considering adequacy of allocation concealment
• Trial sequential analyses of six meta-analyses considering heterogeneity and trial weight
• Trial Sequential Analysis controls random error risks in systematic review meta-analyses
• Trial sequential analysis for cumulative evidence: how much was believable?
• Trial sequential analysis in meta-analyses: could all evidence be firm?
• Trial Sequential Meta-Analysis with R
• Trial summary report software and database specifications and preliminary results
• Trial tracking in guidelines surveillance: Case studies
• Trials at the Cochrane/Campbell interface
• Trials Of heart diseases in developing countries
• Trials of tuberculosis-prevention interventions in Africa: A descriptive cross-sectional study
• Trials reported as abstracts and full publications: how do they compare?
• Trials reported in abstracts: the need for a mini-CONSORT
• Trials Search Co-ordinators and the IMS
• Trials Search Co-ordinators' discussion forum (advanced)
• Trials we cannot trust: investigating their impact on systematic reviews and clinical guidelines in spinal pain
• TRIPOD-SRMA: Reporting guideline for transparent reporting of systematic reviews and meta-analyses of prediction model studies
• True methodological quality of trials are not reflected in their reporting
• Trust but Verify- The Pro and Cons of Transparency in Point-of-Care Evidence Summaries
  
• Trusting what you see: the importance of images shared with evidence for health decision-making and how to get it right
• Trusts, foundations, and the EU: strategies for accessing new funding sources
• Trustworthy clinical practice guidelines: a national project in the Czech Republic
• Trustworthy digital evidence ecosystem to improve diagnosis and treatment of patients
• Trustworthy stopping criteria for reliable work savings from machine learning prioritised screening
• Trying to introduce systematic comparisons between randomized and non-randomized studies into the surgery field: a case report
• Tuberculosis clinical trial activity on the African continent: an analysis of tuberculosis trials registered on the Pan African Clinical Trials Registry and WHO-ICTRP
• Tunisian Emergency referential : from redaction to implementation
• Turbidimetric d-dimer in the diagnosis of pulmonary embolism: a meta-analysis
• Turning a scientific procedure into an online participative tool
• Turning knowledge into action: Translating Cochrane reviews in the healthcare setting
• Tutorship program to enhance quality and reporting of clinical practice guidelines: findings from Brazilian clinical guidelines
• Two examples of synergy between an Academic institution and policymakers in Argentina
• Two reviews are better than one? Developing linkages between a Cochrane review and a review of mixed methods
• Two years down, one to go: an NIHR programme grant in numbers
• Two years' experience for training appraisers of guidelines using an AGREE II scoring guide in Korea
• Two-year follow up in a breast-screening decision aid RCT: Retention of overdetection knowledge and other decision-making effects
• Type 1 diabetes in children - touching the void in research evidence
• Type-1-diabetes: the problems associated with comparing Integrated Sensor-Augmented Pump Therapy systems for managing blood glucose levels with multiple daily injections
• Types of selective inclusion and reporting bias in randomised trials and systematic reviews of randomised trials
• Typhoon Haiyan: the impact of free access
• UK Co-ordinating Editor Quality Control Pilot Scheme (aka The QUACk Scheme)
• UK filter project: methodological approach to reduce information overload by developing validated UK geographic search filters for MEDLINE and Embase
• UK prioritisation methods for Cochrane Reviews
• Ultra-rapid HTAs: a survey of usefulness and influence in decision making
• Ultra-rapid synthesis of secondary sources for hospital COVID-19 guidance
• Ultrasound therapy for musculoskeletal disorders: evaluating efficacy, setting priorities for research and for implementing the evidence
• Umbrella reviews: development and reporting of an approach to summarize systematic reviews
• Umbrella workshops
• UN Decade of Healthy Ageing 2020-30: how can the evidence synthesis community contribute?
• Uncertainty in baseline risk can reduce confidence in estimates of effect
• Uncertainty in control group risk can, in systematic reviews, undermine confidence in estimates of effect
• Uncertainty of heterogeneity in meta-analyses
• Uncommon language: The challenges of inconsistent terminology use for evidence synthesis
• Under-reporting of outcomes is prevalent and inflates effect size estimates in Cochrane reviews
• Underestimation of depression screening-tool sensitivity when using lay-administered, fully structured diagnostic interviews as the reference standard
• Underreporting of conflicts of interest among authors of clinical drug trials: cross sectional study
• Underreporting of conflicts of interest in clinical practice guidelines: cross sectional study
• Understanding and addressing vaccine hesitancy in the prison setting: a quasi-experimental study in four European countries
• Understanding and strengthening knowledge translation platforms (KTPs): a scoping review
• Understanding barriers and approaches to communicating health economic evidence: systematic review and needs assessment
• Understanding challenges of managing ischemic heart disease in primary care to inform the scoping of a national clinical guidance
  
• Understanding clinicians’ perceptions of, endorsements of, and intentions to use cancer practice guidelines
• Understanding complex issues of GP retention using a visual model to interface qualitative evidence synthesis, patient involvement and primary research
• Understanding context in evidence synthesis and guideline development – connecting global evidence and local needs
• Understanding evidence: machine learning and artificial intelligence in the Human Behaviour-Change Project
• Understanding how meta-analysts interpret meta-analyses
• Understanding implementation research: Case study from the HIFA virtual discussion forum
• Understanding patients, physicians and caregivers’s perspectives on Artificial Intelligence：A targeted review of qualitative studies
• Understanding reporting and publication patterns of systematic reviews of medical education
• Understanding subjectivity in the meta-analytic process: Meta-analysts' variation in managing variability
• Understanding the barriers and facilitators for developing and implementing evidence-based practice guidelines during a pandemic: Protocol for exploratory mixed-methods study
  
• Understanding the Contents and Gaps in Sexual and Reproductive Health Toolkits Designed for Adolescence and Young Adults: A Systematic Review
• Understanding the determinants WHO guideline panels consider in making strong recommendations in the face of low or very low confidence (study quality) in effect estimates
• Understanding the evidence-informed decision-making landscape in Africa: actors, engagement and skills
• Understanding the health impacts of climate change: search filter development for exposure pathways
• Understanding the impact of outcome reporting bias in trials (the ORBIT study)
• Understanding the mechanisms of trial discontinuation due to poor recruitment: Interviews with stakeholders in clinical trials
• Understanding the process and impact of within-study selective reporting bias
• Understanding the process and impact of within-study selective reporting bias for harm outcomes (ORBIT II—outcome reporting bias in trials)
• Understanding the relationship between risks and odds ratios
• Understanding, appraising and reporting systematic reviews that use individual participant data
• Undertaking a mixed methods Cochrane Review of school-based asthma interventions: logic, learning and results
• Undertaking a systematic review addressing a question of prevalence
• Undertaking overview of systematic reviews – methods, challenges and the way forward (as identified by a group of clinical academics and methodologists who recently figured it all out)
• UNED: a strategy to strengthen evidence-informed decision-making in Colombia
  
• Unfudging nudging: identifying evidence for poorly-specified interventions in public health
• Unique methodological challenges to incorporating studies on food taxation into Cochrane Reviews: comparing Cochrane EPOC and Reeves et al 2017 study design classifications
• Unique trial identification numbers are underreported in biomedical publications
• Uniqueness of conducting systematic reviews and developing nutrition practice guidelines: Experiences and challenges from Academy’s EAL
• Unit of analysis errors in meta-analyses of exposure to plastic chemicals
  
• Univariable meta-regression may be more conservative compared to chi-square in sub-group analyses
• Univariate and multivariate prognostic indexes to evaluate treatment efficacy in a systematic overview
• University conflict of interest policies for health research and education: a scoping review
• Unknown knowns: use of Cochrane review results in designing new studies
• Unlocking Healthcare Insights: The Power of Best Practice Information Sheets (BPIS) in Disseminating Systematic Review Findings
  
• Unlocking innovations for sharing and using Cochrane content with study centric data management and a focused review article
• Unlocking the DOOR to build transparent composite primary outcomes for chronic myeloproliferative neoplasms
• Unlocking the future MedTech innovation landscape: the application of evidence synthesis methods to improve outputs and reporting
• Unlocking the key to empower citizens in digital health data governance: insights from an overview of reviews
• Unlocking the potential of artificial intelligence in the systematic review process: a special session with Cochrane's Methods Executive
• Unlocking young minds: findings from a national survey on critical thinking on health in Polish primary schools (LIGHT)
  
• Unmet health care needs in Brazilian National Health System: mapping diseases without clinical protocols and therapeutic guidelines
• Unmet needs of patients transitioning to secondary progressive multiple sclerosis: Qualitative findings for a resource development
• Unnecessary pooling of heterogeneous data: Analysis of a sample of systematic reviews
• Unnecessary repetitions of pediatric clinical trials: cumulative meta-analyses
• Unpackaging context dependence in systematic reviews of complex interventions: a methodological approach for managing double-layered complexity
• Unplanned crossover in randomised controlled trials: Consequences for efficacy and safety outcomes
• Unpublished data from United States Food and Drug Administration New Drug Application Reviews: How Do They Compare to Published Data when Assessing Nonsteroidal Antiinflammatory Drug (NSAID) Associated Dyspepsia?
• Unpublished systematic reviews and financial support: a meta-epidemiological study
• Unpublished trials in molluscum contagiosum: a case study in publication bias
• Unraveling education needs for clinical practice guideline development: a survey in the Netherlands
• Unravelling active ingredients of task-shifting interventions in low-resource settings for common mental disorders: developing a taxonomy of intervention components and ranking their efficacy.
• Unreported trial amnesty
• Untangling the maze of the trial selection process
• Untapped potential for systematic review software & automation to reduce the 6 million hours spent on title/abstract screening annually
• Unveiling a Decade of Excellence in Evidence: 10 years of the first Academic League of Evidence-Based Medicine in Brazil
• Update of Cochrane Systematic Review of audit and feedback demonstrates stability in findings. Will future trials be helpful?
• Update of PRISMA guidelines for network meta-analyses
• Update of the Cochrane Review of interventions for preventing obesity in children: priority setting
• Update of the Cochrane systematic review of interventions for preventing obesity in children: a research program
• Update of the Cochrane systematic review of interventions for preventing obesity in children: overview of systematic reviews
• Update of the EPOC methodological search filter
• Update of the European guidelines on breast cancer screening and diagnosis: updated recommendations and new topics
  
• Update Process of the Clinical Practice Guideline on Palliative Care within the Spanish National Health System Guidelines Program
• Updated Brazilian guidelines for health economic evaluation in public system
• Updated Brazilian guidelines of GRADE system to evidence synthesis
• Updated critical appraisal tools for systematic reviews of textual evidence: narrative, expert opinion, and policy
• Updating a Clinical Practice Guideline on Insomnia for Primary Care: evidence from Systematic Reviews and a Qualitative Study.
  
• Updating a review of nicotine replacement therapy. What difference does it make?
• Updating a Systematic Review and Meta-Analysis: First Annual Update of Sexual Risk reduction Effects Following HIV Intervention
• Updating an evidence-based clinical guideline for providing care to cancer patients receiving myelosuppressive chemotherapy and/or radiotherapy in hospital in Taiwan
• Updating an Evidence-based Clinical Guideline for Providing Oral Care in Chemotherapy and Radiotherapy Cancer Patients in a Hospital in Taiwan
  
• Updating blood pressure targets in Singapore – insights from developing an ACE Clinical Guidance for hypertension management
  
• Updating Clinical Practice Guidelines in a Field with Limited Evidence: American Society of Hematology Pediatric Venous Thromboembolism Treatment Guideline
• Updating Cochrane reviews: vigilance required?
• Updating DataBase: an open access living repository of methodological documents about updating systematic reviews and clinical guidelines
• Updating for quality: reflections on our editorial policy
• Updating gap in Cochrane systematic reviews: an observational pilot study. Preliminary results
• Updating guidelines for reporting systematic reviews and meta-analyses: development of the PRISMA 2020 statement
• Updating JBI guidance for conducting systematic reviews of etiology and risk
• Updating national guidelines with recommendations of duration of sickness absence and as a tool for assessing work ability
• Updating patient information: a literature review
• Updating QUADAS: User experience informs the development of QUADAS-2
• Updating recommendations in guidelines using new tools. Which approach is more efficient?
• Updating Searches for Evidence Synthesis: The good, the bad and the ugly
• Updating systematic reviews can improve the precision of outcomes: a comparative study
• Updating systematic reviews published in Chinese: a cross-sectional study
• Updating systematic reviews with active learning
• Updating systematic reviews: an international survey
• Updating the evidence for German geriatric medicine: an approach inspired by Cochrane Living Systematic Reviews
• Updating the National Disease Management Guideline for Non-specific Chronic Low Back Pain – a best-practice example
• Updating the web-based "Right Review" tool: an international Delphi process
• UpGlossary: Guidance on terminology and definitions for updating clinical guidelines
• Upgrading the quality of evidence from RCTs? Examples from published summary of findings tables
• Uptake and Implementation of GRADE among guideline developers in the United States
• Uptake and influential factors of randomized trials in Cochrane systematic reviews of acupuncture
• Uptake of Cochrane Acute Respiratory Infections reviews in primary care guidelines
• Uptake of core outcome sets (COSs) in China
• Uptake of newer methodological developments and the deployment of meta-analysis in diagnostic test research – A systematic review
• Uptake of systematic reviews and meta-analyses in health policy briefs: an analysis of references
• Ursodeoxycholic Acid for Primary Biliary Cirrhosis - a Systematic Review
• US Cochrane Network-Who are we?
• US Patent documents on the Internet: an unexplored source of unpublished clinical trials
• Usability of Cochrane-based evidence summaries in point-of-care guidelines
• Usage and acceptance of adjusted indirect comparisons in IQWiG reports in the period 2011 to 2016
• Usage of Cochrane reviews in The World Health Organization (WHO) Reproductive Health Library
• Usage of evidence from Cochrane reviews in evidence synthesis to support judiciary decision-making in Brazil
  
• USDA Nutrition Evidence Library: producing systematic reviews to support evidence-based federal nutrition guidance and programs in the USA
• Use and acceptability of third-party network meta-analysis tools in conducting reviews among Cochrane authors
• Use and methodology of framework synthesis in mixed-methods literature reviews
• Use and process of adjudication committees in randomised controlled trials
• Use and quality of Cochrane Reviews used in knee and hip osteoarthritis clinical practice guidelines
• Use i-PARIHS framework to develop evidence implementation strategies for central venous catheter maintenance: a multisite quality improvement project
  
• Use of a wiki-based educational resource as a knowledge translation intervention to improve research in child health
• Use of an advisory group to ensure relevance: reflections on participation of stakeholders in a review of sexual health promotion for men who have sex with men (MSM)
• Use of an influence-interest grid for stakeholder analysis to develop a national engagement and implementation programme
• Use of Cochrane bladder cancer reviews: confirming the need for Wikiproject Medicine and assessing what is ‘UpToDate’
• Use of Cochrane Evidence in Mexican clinical practice guidelines
• Use of Cochrane Library in consensus conference on childhood asthma
• Use of Cochrane nutrition reviews in guidelines: appraising the 'payback' on investing in nutrition evidence synthesis
• Use of Cochrane Reviews in developing Clinical Practice Guidelines (CPGs) in Malaysia
• Use of Cochrane reviews in guidelines for general practitioners
• Use of Cochrane Reviews in nationally developed clinical practice guidelines in Latin America
• Use of Cochrane Reviews in NICE Clinical Guidelines
• Use of Cochrane reviews in the Canadian common drug review reports
• Use of Cochrane Reviews to inform the health policy-making process in a rapid evidence synthesis program in Chile
• Use of composite endpoints in cardiovascular trials
• Use of consumer and guideline user surveys in the development of a consensus-based guideline on sports preparticipation evaluations