• Transparent two stage approach to identification and selection of qualitative literature for meta ethnographic synthesis
• Transparent, explicit, intuitive: Bayesian updating of Cochrane reviews
• Travelling to the tropics? How to enrich a systematic review with good observational evidence about adverse effects
• Treatment adequacy of Chinese medicine in Cochrane systematic reviews: an investigation
• Treatment benefit cannot be excluded on the basis of mean difference alone
• Treatment decision by patient participation: a preliminary study based on the workpiece of shared decision making in medicine
• Treatment effect estimates for nontruncated trials need adjustment when conducting sensitivity analyses to assess risk of bias in early-stopped trials
• Treatment effect sizes vary in randomized trials depending on type of outcome measure
• Treatment effects from the patient perspective: understanding the alternatives to intention-to-treat analyses
• Treatment guidelines in specialist mental healthcare: how important are they and how to translate them into practice?
• Treatment information-seeking by people with multiple sclerosis in the internet age: Stage 1 findings of the IN-DEEP project
• Treatment of acute migraine attacks in children with analgesics on the World Health Organization Essential Medicines List: A systematic review
• Treatment of chronic cerebrovascular disorders with the metabolic activators compared to placebo: a cumulative meta-analysis
• Treatment of heterogeneity in systematic reviews of diagnostic tests in cancer
• Treatment of multiple test readers in diagnostic accuracy systematic reviews of imaging studies
• Treatment of quasi-randomised trials in Cochrane Reviews
• Treatment related harms: what was planned and what was reported? An analysis of Southwest Oncology Group phase III trials
• Treatment uncertainties in blood donation and blood transfusion: involvement of patients and donors as well as clinicians
• Treatments for Bullous Pemphigoid - A systematic review
• Treatments for plantar heel pain
• Trends analysis of cancer topic of Cochrane Systematic Reviews: a bibliometric analysis
• Trends in methodological quality of randomised clinical trials in low back pain: comparing drug trials with non-drug trials
• Trends in randomized controlled trials of malaria treatment and prophylaxis in Africa
• Trends in reported allocation concealment in RCTs included in systematic reviews
• Trends in use and costs of lumbar and full spine radiography by chiropractors in Ontario: a review of Ontario Health Insurance Plan and Workplace Safety and Insurance Board data from 1994 to 2001
• Trends over time in the size and quality of randomised controlled trials of interventions for chronic low-back pain
• TRiads-P: A translational research programme to promote evidence-based practice in the community pharmacy setting
• Trial Characteristics and Treatment Effect Estimates in Randomized Controlled Trials of Chinese Herbal Medicine: A Meta-Epidemiological Study
• Trial data available in FDA and EMA reports: a cross-sectional study
• Trial investigators as authors of Cochrane reviews: do we manage conflicts of interests adequately?
• Trial publication after registration in Clinical Trials Registry of India (CTRI): a cross-sectional analysis of randomized controlled trials
• Trial Registers: What Do Users Really Really Want?
• Trial registration can be a useful source of information for quality assessment: a study of trials records retrieved from the WHO search portal
• Trial results in clinical trial registries – towards more transparency in clinical research
• Trial sequential analyses of 145 Cochrane Neonatal Group meta-analyses considering adequacy of allocation concealment and heterogeneity
• Trial sequential analyses of meta-analyses from a Cochrane review of targeting intensive versus conventional glycaemic control in patients with type 2 diabetes
• Trial sequential analyses of six Cochrane neonatal group meta-analyses considering adequacy of allocation concealment
• Trial sequential analyses of six meta-analyses considering heterogeneity and trial weight
• Trial Sequential Analysis controls random error risks in systematic review meta-analyses
• Trial sequential analysis for cumulative evidence: how much was believable?
• Trial sequential analysis in meta-analyses: could all evidence be firm?
• Trial Sequential Meta-Analysis with R
• Trial summary report software and database specifications and preliminary results
• Trial tracking in guidelines surveillance: Case studies
• Trials at the Cochrane/Campbell interface
• Trials Of heart diseases in developing countries
• Trials of tuberculosis-prevention interventions in Africa: A descriptive cross-sectional study
• Trials reported as abstracts and full publications: how do they compare?
• Trials reported in abstracts: the need for a mini-CONSORT
• Trials Search Co-ordinators and the IMS
• Trials Search Co-ordinators' discussion forum (advanced)
• Trials we cannot trust: investigating their impact on systematic reviews and clinical guidelines in spinal pain
• TRIPOD-SRMA: Reporting guideline for transparent reporting of systematic reviews and meta-analyses of prediction model studies
• True methodological quality of trials are not reflected in their reporting
• Trusting what you see: the importance of images shared with evidence for health decision-making and how to get it right
• Trusts, foundations, and the EU: strategies for accessing new funding sources
• Trustworthy clinical practice guidelines: a national project in the Czech Republic
• Trustworthy digital evidence ecosystem to improve diagnosis and treatment of patients
• Trustworthy stopping criteria for reliable work savings from machine learning prioritised screening
• Trying to introduce systematic comparisons between randomized and non-randomized studies into the surgery field: a case report
• Tuberculosis clinical trial activity on the African continent: an analysis of tuberculosis trials registered on the Pan African Clinical Trials Registry and WHO-ICTRP
• Turbidimetric d-dimer in the diagnosis of pulmonary embolism: a meta-analysis
• Turning a scientific procedure into an online participative tool
• Turning knowledge into action: Translating Cochrane reviews in the healthcare setting
• Two examples of synergy between an Academic institution and policymakers in Argentina
• Two reviews are better than one? Developing linkages between a Cochrane review and a review of mixed methods
• Two years down, one to go: an NIHR programme grant in numbers
• Two years' experience for training appraisers of guidelines using an AGREE II scoring guide in Korea
• Two-year follow up in a breast-screening decision aid RCT: Retention of overdetection knowledge and other decision-making effects
• Type 1 diabetes in children - touching the void in research evidence
• Type-1-diabetes: the problems associated with comparing Integrated Sensor-Augmented Pump Therapy systems for managing blood glucose levels with multiple daily injections
• Types of selective inclusion and reporting bias in randomised trials and systematic reviews of randomised trials
• Typhoon Haiyan: the impact of free access
• UK Co-ordinating Editor Quality Control Pilot Scheme (aka The QUACk Scheme)
• UK filter project: methodological approach to reduce information overload by developing validated UK geographic search filters for MEDLINE and Embase
• UK prioritisation methods for Cochrane Reviews
• Ultra-rapid HTAs: a survey of usefulness and influence in decision making
• Ultra-rapid synthesis of secondary sources for hospital COVID-19 guidance
• Ultrasound therapy for musculoskeletal disorders: evaluating efficacy, setting priorities for research and for implementing the evidence
• Umbrella reviews: development and reporting of an approach to summarize systematic reviews
• Umbrella workshops
• Uncertainty in baseline risk can reduce confidence in estimates of effect
• Uncertainty in control group risk can, in systematic reviews, undermine confidence in estimates of effect
• Uncertainty of heterogeneity in meta-analyses
• Uncommon language: The challenges of inconsistent terminology use for evidence synthesis
• Under-reporting of outcomes is prevalent and inflates effect size estimates in Cochrane reviews
• Underestimation of depression screening-tool sensitivity when using lay-administered, fully structured diagnostic interviews as the reference standard
• Underreporting of conflicts of interest among authors of clinical drug trials: cross sectional study
• Underreporting of conflicts of interest in clinical practice guidelines: cross sectional study
• Understanding barriers and approaches to communicating health economic evidence: systematic review and needs assessment
• Understanding clinicians’ perceptions of, endorsements of, and intentions to use cancer practice guidelines
• Understanding complex issues of GP retention using a visual model to interface qualitative evidence synthesis, patient involvement and primary research
• Understanding context in evidence synthesis and guideline development – connecting global evidence and local needs
• Understanding evidence: machine learning and artificial intelligence in the Human Behaviour-Change Project
• Understanding how meta-analysts interpret meta-analyses
• Understanding implementation research: Case study from the HIFA virtual discussion forum
• Understanding patients, physicians and caregivers’s perspectives on Artificial Intelligence：A targeted review of qualitative studies
• Understanding reporting and publication patterns of systematic reviews of medical education
• Understanding subjectivity in the meta-analytic process: Meta-analysts' variation in managing variability
• Understanding the determinants WHO guideline panels consider in making strong recommendations in the face of low or very low confidence (study quality) in effect estimates
• Understanding the evidence-informed decision-making landscape in Africa: actors, engagement and skills
• Understanding the health impacts of climate change: search filter development for exposure pathways
• Understanding the impact of outcome reporting bias in trials (the ORBIT study)
• Understanding the mechanisms of trial discontinuation due to poor recruitment: Interviews with stakeholders in clinical trials
• Understanding the process and impact of within-study selective reporting bias
• Understanding the process and impact of within-study selective reporting bias for harm outcomes (ORBIT II—outcome reporting bias in trials)
• Understanding the relationship between risks and odds ratios
• Understanding, appraising and reporting systematic reviews that use individual participant data
• Undertaking a mixed methods Cochrane Review of school-based asthma interventions: logic, learning and results
• Undertaking a systematic review addressing a question of prevalence
• Undertaking overview of systematic reviews – methods, challenges and the way forward (as identified by a group of clinical academics and methodologists who recently figured it all out)
• Unfudging nudging: identifying evidence for poorly-specified interventions in public health
• Unique methodological challenges to incorporating studies on food taxation into Cochrane Reviews: comparing Cochrane EPOC and Reeves et al 2017 study design classifications
• Unique trial identification numbers are underreported in biomedical publications
• Uniqueness of conducting systematic reviews and developing nutrition practice guidelines: Experiences and challenges from Academy’s EAL
• Univariable meta-regression may be more conservative compared to chi-square in sub-group analyses
• Univariate and multivariate prognostic indexes to evaluate treatment efficacy in a systematic overview
• University conflict of interest policies for health research and education: a scoping review
• Unknown knowns: use of Cochrane review results in designing new studies
• Unlocking innovations for sharing and using Cochrane content with study centric data management and a focused review article
• Unmet needs of patients transitioning to secondary progressive multiple sclerosis: Qualitative findings for a resource development
• Unnecessary pooling of heterogeneous data: Analysis of a sample of systematic reviews
• Unnecessary repetitions of pediatric clinical trials: cumulative meta-analyses
• Unpackaging context dependence in systematic reviews of complex interventions: a methodological approach for managing double-layered complexity
• Unplanned crossover in randomised controlled trials: Consequences for efficacy and safety outcomes
• Unpublished data from United States Food and Drug Administration New Drug Application Reviews: How Do They Compare to Published Data when Assessing Nonsteroidal Antiinflammatory Drug (NSAID) Associated Dyspepsia?
• Unpublished systematic reviews and financial support: a meta-epidemiological study
• Unpublished trials in molluscum contagiosum: a case study in publication bias
• Unravelling active ingredients of task-shifting interventions in low-resource settings for common mental disorders: developing a taxonomy of intervention components and ranking their efficacy.
• Unreported trial amnesty
• Untangling the maze of the trial selection process
• Update of Cochrane Systematic Review of audit and feedback demonstrates stability in findings. Will future trials be helpful?
• Update of the Cochrane Review of interventions for preventing obesity in children: priority setting
• Update of the Cochrane systematic review of interventions for preventing obesity in children: a research program
• Update of the Cochrane systematic review of interventions for preventing obesity in children: overview of systematic reviews
• Update of the EPOC methodological search filter
• Updating a review of nicotine replacement therapy. What difference does it make?
• Updating a Systematic Review and Meta-Analysis: First Annual Update of Sexual Risk reduction Effects Following HIV Intervention
• Updating Cochrane reviews: vigilance required?
• Updating DataBase: an open access living repository of methodological documents about updating systematic reviews and clinical guidelines
• Updating for quality: reflections on our editorial policy
• Updating gap in Cochrane systematic reviews: an observational pilot study. Preliminary results
• Updating guidelines for reporting systematic reviews and meta-analyses: development of the PRISMA 2020 statement
• Updating national guidelines with recommendations of duration of sickness absence and as a tool for assessing work ability
• Updating patient information: a literature review
• Updating QUADAS: User experience informs the development of QUADAS-2
• Updating recommendations in guidelines using new tools. Which approach is more efficient?
• Updating Searches for Evidence Synthesis: The good, the bad and the ugly
• Updating systematic reviews can improve the precision of outcomes: a comparative study
• Updating systematic reviews published in Chinese: a cross-sectional study
• Updating systematic reviews with active learning
• Updating systematic reviews: an international survey
• Updating the evidence for German geriatric medicine: an approach inspired by Cochrane Living Systematic Reviews
• Updating the National Disease Management Guideline for Non-specific Chronic Low Back Pain – a best-practice example
• Updating the web-based "Right Review" tool: an international Delphi process
• UpGlossary: Guidance on terminology and definitions for updating clinical guidelines
• Upgrading the quality of evidence from RCTs? Examples from published summary of findings tables
• Uptake and Implementation of GRADE among guideline developers in the United States
• Uptake and influential factors of randomized trials in Cochrane systematic reviews of acupuncture
• Uptake of Cochrane Acute Respiratory Infections reviews in primary care guidelines
• Uptake of newer methodological developments and the deployment of meta-analysis in diagnostic test research – A systematic review
• Uptake of systematic reviews and meta-analyses in health policy briefs: an analysis of references
• Ursodeoxycholic Acid for Primary Biliary Cirrhosis - a Systematic Review
• US Cochrane Network-Who are we?
• US Patent documents on the Internet: an unexplored source of unpublished clinical trials
• Usability of Cochrane-based evidence summaries in point-of-care guidelines
• Usage and acceptance of adjusted indirect comparisons in IQWiG reports in the period 2011 to 2016
• Usage of Cochrane reviews in The World Health Organization (WHO) Reproductive Health Library
• USDA Nutrition Evidence Library: producing systematic reviews to support evidence-based federal nutrition guidance and programs in the USA
• Use and acceptability of third-party network meta-analysis tools in conducting reviews among Cochrane authors
• Use and methodology of framework synthesis in mixed-methods literature reviews
• Use and process of adjudication committees in randomised controlled trials
• Use and quality of Cochrane Reviews used in knee and hip osteoarthritis clinical practice guidelines
• Use of a wiki-based educational resource as a knowledge translation intervention to improve research in child health
• Use of an advisory group to ensure relevance: reflections on participation of stakeholders in a review of sexual health promotion for men who have sex with men (MSM)
• Use of an influence-interest grid for stakeholder analysis to develop a national engagement and implementation programme
• Use of Cochrane bladder cancer reviews: confirming the need for Wikiproject Medicine and assessing what is ‘UpToDate’
• Use of Cochrane Evidence in Mexican clinical practice guidelines
• Use of Cochrane Library in consensus conference on childhood asthma
• Use of Cochrane nutrition reviews in guidelines: appraising the 'payback' on investing in nutrition evidence synthesis
• Use of Cochrane Reviews in developing Clinical Practice Guidelines (CPGs) in Malaysia
• Use of Cochrane reviews in guidelines for general practitioners
• Use of Cochrane Reviews in nationally developed clinical practice guidelines in Latin America
• Use of Cochrane Reviews in NICE Clinical Guidelines
• Use of Cochrane reviews in the Canadian common drug review reports
• Use of Cochrane Reviews to inform the health policy-making process in a rapid evidence synthesis program in Chile
• Use of composite endpoints in cardiovascular trials
• Use of continuous outcome measures in systematic reviews
• Use of evidence from low- to middle-income countries in a national public health guidance programme
• Use of evidence in economic decision models: an appraisal of health technology assessments in the UK since 1997
• Use of Evidence to Decision frameworks in the European Breast Guidelines: increasing stakeholder involvement and transparency
• Use of Evidence-based nursing (EBN) by nurses in Belgium
• Use of Field Topic Lists in Archie
• Use of filters in electronic searching for observational studies
• Use of framework synthesis to prioritise systematic review topics among multiple stakeholders: a descriptive case study
• Use of GRADE approach to rate the certainty of evidence from network meta-analyses: a cross-sectional survey
• Use of GRADE in Chinese clinical practice guidelines
• Use of GRADE in Dentistry Systematic Reviews: A Methodological Study
• Use of GRADE in the Non-Cochrane Systematic Reviews of Diagnostic Test Accuracy
• Use of Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology to guide revision of CDC’s hepatitis C virus (HCV) testing recommendations for persons born during 1945 through 1965 in the United States